Pharmacological intervention in oxidative stress as a therapeutic target in neurological disorders

Oxidative stress is a major cellular burden that triggers reactive oxygen species (ROS) and antioxidants that modulate signalling mechanisms. Byproducts generated from this process govern the brain pathology and functions in various neurological diseases. As oxidative stress remains the key therapeu...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2022-04, Vol.74 (4), p.461-484
Hauptverfasser:	Sharma, Sudhanshu, Advani, Dia, Das, Ankita, Malhotra, Nishtha, Khosla, Akanksha, Arora, Vanshika, Jha, Ankita, Yadav, Megha, Ambasta, Rashmi K, Kumar, Pravir
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Antioxidants - pharmacology Antioxidants - therapeutic use Humans NADPH Oxidases - metabolism Neurodegenerative Diseases - drug therapy Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology Oxidative Stress Reactive Oxygen Species - metabolism
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