Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis

Preclinical data suggest that the ageing-induced miR-34a regulates vascular senescence. Herein we sought to assess whether the miR-34 family members miR-34a, miR-34b and miR-34c are involved in human arterial disease. Expression levels of miR-34a/b/c were quantified by TaqMan assay in peripheral blo...

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Veröffentlicht in:	Atherosclerosis 2021-06, Vol.327, p.49-58
Hauptverfasser:	Gatsiou, Aikaterini, Georgiopoulos, Georgios, Vlachogiannis, Nikolaos I., Pfisterer, Larissa, Fischer, Ariane, Sachse, Marco, Laina, Ageliki, Bonini, Francesca, Delialis, Dimitrios, Tual-Chalot, Simon, Zormpas, Eleftherios, Achangwa, Rawlings, Jiang, Longchang, Kontogiannis, Christos, Patras, Raphael, Hermeking, Heiko, Zeiher, Andreas M., Stamatelopoulos, Kimon, Dimmeler, Stefanie, Stellos, Konstantinos
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Atherosclerosis Cardiovascular disease Gene expression Humans Jagged-1 Protein Leukocytes, Mononuclear microRNA MicroRNAs miR-34 Sirtuin 1 Vascular ageing
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