A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord

Central nervous system injury re-initiates neurogenesis in anamniotes (amphibians and fishes), but not in mammals. Activation of the innate immune system promotes regenerative neurogenesis, but it is fundamentally unknown whether this is indirect through the activation of known developmental signali...

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Veröffentlicht in:	Developmental cell 2021-06, Vol.56 (11), p.1617-1630.e6
Hauptverfasser:	Cavone, Leonardo, McCann, Tess, Drake, Louisa K., Aguzzi, Erika A., Oprişoreanu, Ana-Maria, Pedersen, Elisa, Sandi, Soe, Selvarajah, Jathurshan, Tsarouchas, Themistoklis M., Wehner, Daniel, Keatinge, Marcus, Mysiak, Karolina S., Henderson, Beth E.P., Dobie, Ross, Henderson, Neil C., Becker, Thomas, Becker, Catherina G.
Format:	Artikel
Sprache:	eng
Schlagworte:	AP-1 HDAC1 macrophages microglia neural stem cells regeneration spinal cord TNFRSF1
Online-Zugang:	Volltext
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