Personalized Variable vs Fixed-Dose Systemic Corticosteroid Therapy in Hospitalized Patients With Acute Exacerbations of COPD: A Prospective, Multicenter, Randomized, Open-Label Clinical Trial

Systemic corticosteroids for the treatment of COPD exacerbations decrease treatment failure and shorten the length of hospitalization. However, the optimal dose is unclear. Is personalized-dose corticosteroid administered according to a dosing scale more effective than fixed-dose corticosteroid admi...

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Veröffentlicht in:	Chest 2021-11, Vol.160 (5), p.1660-1669
Hauptverfasser:	Li, Li, Zhao, Nana, Ma, Xiangyu, Sun, Fenfen, He, Binfeng, Qin, Zhen, Wu, Kui, Wang, Xingsheng, Zhao, Qian, Zhang, Shisi, Nie, Naifu, Luo, Dong, Sun, Bin, Shen, Ye, He, Yong, Wen, Fuqiang, Zheng, Jinping, Jones, Paul, Cao, Guoqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - adverse effects Aged Dose-Response Relationship, Drug Drug Dosage Calculations Female Glucocorticoids - administration & dosage Glucocorticoids - adverse effects Humans Intensive Care Units - statistics & numerical data Length of Stay - economics Length of Stay - statistics & numerical data Male Outcome and Process Assessment, Health Care Patient Readmission - statistics & numerical data Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - mortality Pulmonary Disease, Chronic Obstructive - therapy Symptom Assessment - methods Symptom Flare Up
Online-Zugang:	Volltext
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