Glycyrrhetinic acid derivatives as Zika virus inhibitors: Synthesis and antiviral activity in vitro

[Display omitted] •Glycyrrhetinic acid (GA) derivatives (amides, semi- and thiosemicarbazones, and 1,2,3-thiadiazoles) were synthesized and tested as Zika virus inhibitors in vitro.•Four active compounds were found among GA derivatives tested with IC50 

Bibliographische Detailangaben

Veröffentlicht in:	Bioorganic & medicinal chemistry 2021-07, Vol.41, p.116204-116204, Article 116204
Hauptverfasser:	Baltina, Lidia A., Lai, Hsueh-Chou, Liu, Ya-Chi, Huang, Su-Hua, Hour, Mann-Jen, Baltina, Lia A., Nugumanov, Tagir R., Borisevich, Sophia S., Khalilov, Leonard M., Petrova, Svetlana F., Khursan, Sergey L., Lin, Cheng-Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Derivatives Glycyrrhetinic acid Inhibitors Synthesis Triterpenoids Zika virus
Online-Zugang:	Volltext
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