A New Model for Specific Visualization of Skin Graft Neoangiogenesis Using Flt1-tdsRed BAC Transgenic Mice

Neovascularization plays a critical role in skin graft survival. Up to date, the lack of specificity to solely track the newly sprouting blood vessels has remained a limiting factor in skin graft transplantation models. Therefore, the authors developed a new model by using Flt1-tdsRed BAC transgenic...

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Veröffentlicht in:	Plastic and reconstructive surgery (1963) 2021-07, Vol.148 (1), p.89-99
Hauptverfasser:	Abdelhakim, Mohamed, Dohi, Teruyuki, Yamato, Mizuho, Takada, Hiroya, Sakai, Atsushi, Suzuki, Hidenori, Ema, Masatsugu, Fukuhara, Shigetomo, Ogawa, Rei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement Endothelial Cells Female Genes, Reporter Graft Survival - physiology Intravital Microscopy Luminescent Proteins - genetics Male Mice Mice, Nude Mice, Transgenic Microscopy, Confocal Models, Animal Molecular Imaging - methods Neovascularization, Physiologic Red Fluorescent Protein Skin - blood supply Skin Transplantation Vascular Endothelial Growth Factor Receptor-1 - genetics Wound Healing - physiology
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