FASCIN regulates actin assembly for spindle movement and polar body extrusion in mouse oocyte meiosis

During mouse oocyte meiotic maturation, actin filaments play multiple roles in meiosis such as spindle migration and cytokinesis. FASCIN is shown to be an actin‐binding and bundling protein, making actin filaments tightly packed and parallel‐aligned, and FASCIN is involved in several cellular proces...

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Veröffentlicht in:	Journal of cellular physiology 2021-11, Vol.236 (11), p.7725-7733
Hauptverfasser:	Hu, Lin‐Lin, Pan, Meng‐Hao, Yang, Feng‐Lian, Zong, Zi‐Ao, Tang, Feng, Pan, Zhen‐Nan, Lu, Xiang, Ren, Yan‐Ping, Wang, Jun‐Li, Sun, Shao‐Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actin Cytoskeleton - genetics Actin Cytoskeleton - metabolism Animals Assembly Biomarkers Carrier Proteins - genetics Carrier Proteins - metabolism Cells, Cultured Cytokinesis Depletion Extrusion FASCIN Female Filaments Gametocytes Localization Maturation Meiosis Metastases Mice Mice, Inbred ICR Microfilament Proteins - genetics Microfilament Proteins - metabolism oocyte Oocytes Oocytes - metabolism Polar Bodies - metabolism Protein kinase C Protein Kinase C - metabolism rho GTP-Binding Proteins - metabolism spindle Spindle Apparatus - genetics Spindle Apparatus - metabolism Spindles Therapeutic targets
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