A novel bioanalytical method for the quantification of pemigatinib in rat plasma by UPLC-MS/MS

•First report for determination of pemigatinib in rat plasma.•A quick and simple protein precipitation with acetonitrile was employed.•This novel UPLC-MS/MS method was successfully applied to a PK study. Pemigatinib is an oral, selective, potent, competitive inhibitor acting on fibroblast growth fac...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2021-08, Vol.202, p.114137-114137, Article 114137
Hauptverfasser:	Weng, Qinghua, Tan, Wei, Yu, Ren-yue, Xu, Ren-ai, Chen, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Pemigatinib Pharmacokinetic Rat Sample preparation UPLC-MS/MS
Online-Zugang:	Volltext
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