Prevalence of Moderate to Severe Anxiety Symptoms among Patients with Myocardial Infarction: a Meta-Analysis
This study attempted to synthesize the evidence on the prevalence of moderate to severe anxiety symptoms among myocardial infarction (MI) patients to offer a reliable and accurate estimate on the number of MI patients suffering from moderate to severe anxiety symptoms. Comprehensive electronic searc...
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| Veröffentlicht in: | Psychiatric quarterly 2022-03, Vol.93 (1), p.161-180 |
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| container_title | Psychiatric quarterly |
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| creator | Lian, Yajun Xiang, Jingsha Wang, Xiaoyan Kaminga, Atipatsa C. Chen, Wenhang Lai, Zhiwei Dai, Wenjie Yang, Jianzhou |
| description | This study attempted to synthesize the evidence on the prevalence of moderate to severe anxiety symptoms among myocardial infarction (MI) patients to offer a reliable and accurate estimate on the number of MI patients suffering from moderate to severe anxiety symptoms. Comprehensive electronic searches (PubMed, Embase and Web of Science) were performed from their inception to February 2021. Between-study heterogeneity was analyzed using the Cochran’s
Q
test and
I
2
statistic, and if it was high across the eligible studies, meta-regression and subgroup analyses were conducted to examine the source of heterogeneity. Publication bias and the robustness of the pooled results were also examined. A total of 18 eligible studies covering 8,532 MI patients were included, of which 3,443 were identified with moderate to severe anxiety symptoms. Between-study heterogeneity was high (
I
2
=98.8%) with the reported prevalence ranging from 9.6% to 69.17%, and the pooled prevalence was 38.08% (95% confidence interval: 28.82–47.81%) by a random-effects model. Meta-regression analyses indicated that publication year (
β
= −0.014) was significant moderators contributing 16.11% to the heterogeneity. Subgroup analyses indicated that studies using the anxiety subscale of Brief Symptom Inventory to assess anxiety were homogenous (
I
2
=0.0). Furthermore, the pooled prevalence of moderate to severe anxiety symptoms varied significantly by geographic region, instrument used to assess anxiety, methodological quality, sex, education level, a history of previous MI and hypercholesterolemia. Additionally, the results of Egger’s linear test (
t
= −0.630) and Begg’s rank test (
z
= −0.190) indicated no evidence of publication bias, and the sensitivity of the pooled results was low. Nearly two fifth of MI patients suffered from moderate to severe anxiety symptoms, which emphasizes the importance of early identification of anxiety symptoms after MI, as well as the need of implementing psychological interventions for those with elevated anxiety symptoms. |
| doi_str_mv | 10.1007/s11126-021-09921-y |
| format | Article |
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Q
test and
I
2
statistic, and if it was high across the eligible studies, meta-regression and subgroup analyses were conducted to examine the source of heterogeneity. Publication bias and the robustness of the pooled results were also examined. A total of 18 eligible studies covering 8,532 MI patients were included, of which 3,443 were identified with moderate to severe anxiety symptoms. Between-study heterogeneity was high (
I
2
=98.8%) with the reported prevalence ranging from 9.6% to 69.17%, and the pooled prevalence was 38.08% (95% confidence interval: 28.82–47.81%) by a random-effects model. Meta-regression analyses indicated that publication year (
β
= −0.014) was significant moderators contributing 16.11% to the heterogeneity. Subgroup analyses indicated that studies using the anxiety subscale of Brief Symptom Inventory to assess anxiety were homogenous (
I
2
=0.0). Furthermore, the pooled prevalence of moderate to severe anxiety symptoms varied significantly by geographic region, instrument used to assess anxiety, methodological quality, sex, education level, a history of previous MI and hypercholesterolemia. Additionally, the results of Egger’s linear test (
t
= −0.630) and Begg’s rank test (
z
= −0.190) indicated no evidence of publication bias, and the sensitivity of the pooled results was low. Nearly two fifth of MI patients suffered from moderate to severe anxiety symptoms, which emphasizes the importance of early identification of anxiety symptoms after MI, as well as the need of implementing psychological interventions for those with elevated anxiety symptoms.</description><identifier>ISSN: 0033-2720</identifier><identifier>EISSN: 1573-6709</identifier><identifier>DOI: 10.1007/s11126-021-09921-y</identifier><identifier>PMID: 34013389</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Anxiety ; Anxiety - epidemiology ; Anxiety Disorders ; Bias ; Heart attacks ; Heterogeneity ; Humans ; Hypercholesterolemia ; Medicine ; Medicine & Public Health ; Meta-analysis ; Moderators ; Myocardial infarction ; Myocardial Infarction - epidemiology ; Prevalence ; Psychiatry ; Public Health ; Review Article ; Risk Assessment ; Robustness ; Severity ; Sociology</subject><ispartof>Psychiatric quarterly, 2022-03, Vol.93 (1), p.161-180</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-4f6d8c77ae034d52cc503cfce92c56be411cdbc37c9ef96f5c8adb00442121b83</citedby><cites>FETCH-LOGICAL-c375t-4f6d8c77ae034d52cc503cfce92c56be411cdbc37c9ef96f5c8adb00442121b83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11126-021-09921-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11126-021-09921-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,12827,27905,27906,30980,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34013389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lian, Yajun</creatorcontrib><creatorcontrib>Xiang, Jingsha</creatorcontrib><creatorcontrib>Wang, Xiaoyan</creatorcontrib><creatorcontrib>Kaminga, Atipatsa C.</creatorcontrib><creatorcontrib>Chen, Wenhang</creatorcontrib><creatorcontrib>Lai, Zhiwei</creatorcontrib><creatorcontrib>Dai, Wenjie</creatorcontrib><creatorcontrib>Yang, Jianzhou</creatorcontrib><title>Prevalence of Moderate to Severe Anxiety Symptoms among Patients with Myocardial Infarction: a Meta-Analysis</title><title>Psychiatric quarterly</title><addtitle>Psychiatr Q</addtitle><addtitle>Psychiatr Q</addtitle><description>This study attempted to synthesize the evidence on the prevalence of moderate to severe anxiety symptoms among myocardial infarction (MI) patients to offer a reliable and accurate estimate on the number of MI patients suffering from moderate to severe anxiety symptoms. Comprehensive electronic searches (PubMed, Embase and Web of Science) were performed from their inception to February 2021. Between-study heterogeneity was analyzed using the Cochran’s
Q
test and
I
2
statistic, and if it was high across the eligible studies, meta-regression and subgroup analyses were conducted to examine the source of heterogeneity. Publication bias and the robustness of the pooled results were also examined. A total of 18 eligible studies covering 8,532 MI patients were included, of which 3,443 were identified with moderate to severe anxiety symptoms. Between-study heterogeneity was high (
I
2
=98.8%) with the reported prevalence ranging from 9.6% to 69.17%, and the pooled prevalence was 38.08% (95% confidence interval: 28.82–47.81%) by a random-effects model. Meta-regression analyses indicated that publication year (
β
= −0.014) was significant moderators contributing 16.11% to the heterogeneity. Subgroup analyses indicated that studies using the anxiety subscale of Brief Symptom Inventory to assess anxiety were homogenous (
I
2
=0.0). Furthermore, the pooled prevalence of moderate to severe anxiety symptoms varied significantly by geographic region, instrument used to assess anxiety, methodological quality, sex, education level, a history of previous MI and hypercholesterolemia. Additionally, the results of Egger’s linear test (
t
= −0.630) and Begg’s rank test (
z
= −0.190) indicated no evidence of publication bias, and the sensitivity of the pooled results was low. Nearly two fifth of MI patients suffered from moderate to severe anxiety symptoms, which emphasizes the importance of early identification of anxiety symptoms after MI, as well as the need of implementing psychological interventions for those with elevated anxiety symptoms.</description><subject>Anxiety</subject><subject>Anxiety - epidemiology</subject><subject>Anxiety Disorders</subject><subject>Bias</subject><subject>Heart attacks</subject><subject>Heterogeneity</subject><subject>Humans</subject><subject>Hypercholesterolemia</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Meta-analysis</subject><subject>Moderators</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Prevalence</subject><subject>Psychiatry</subject><subject>Public Health</subject><subject>Review Article</subject><subject>Risk Assessment</subject><subject>Robustness</subject><subject>Severity</subject><subject>Sociology</subject><issn>0033-2720</issn><issn>1573-6709</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kUFP3DAQha0KVLa0f6AHZIlLLyljO3Hi3lYIKBIrkGjPluNMICixt7YXmn-PYWmROHCZOcz33ozmEfKVwXcGUB9FxhiXBXBWgFK5zh_IglW1KGQNaocsAIQoeM1hj3yK8Q6AMSn4R7InSmBCNGpBxquA92ZEZ5H6nq58h8EkpMnTa7zHgHTp_g6YZno9T-vkp0jN5N0NvTJpQJcifRjSLV3N3prQDWak5643wabBux_U0BUmUyydGec4xM9ktzdjxC8vfZ_8Pj35dfyzuLg8Oz9eXhRW1FUqyl52ja1rgyDKruLWViBsb1FxW8kWS8Zs12bWKuyV7CvbmK4FKEvOOGsbsU--bX3Xwf_ZYEx6GqLFcTQO_SZqXnGlSiElZPTwDXrnNyHfmylZNoJDLVSm-JaywccYsNfrMEwmzJqBfspCb7PQOQv9nIWes-jgxXrTTtj9l_x7fgbEFoh55G4wvO5-x_YRb5KVtA</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Lian, Yajun</creator><creator>Xiang, Jingsha</creator><creator>Wang, Xiaoyan</creator><creator>Kaminga, Atipatsa C.</creator><creator>Chen, Wenhang</creator><creator>Lai, Zhiwei</creator><creator>Dai, Wenjie</creator><creator>Yang, Jianzhou</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2S</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20220301</creationdate><title>Prevalence of Moderate to Severe Anxiety Symptoms among Patients with Myocardial Infarction: a Meta-Analysis</title><author>Lian, Yajun ; 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Comprehensive electronic searches (PubMed, Embase and Web of Science) were performed from their inception to February 2021. Between-study heterogeneity was analyzed using the Cochran’s
Q
test and
I
2
statistic, and if it was high across the eligible studies, meta-regression and subgroup analyses were conducted to examine the source of heterogeneity. Publication bias and the robustness of the pooled results were also examined. A total of 18 eligible studies covering 8,532 MI patients were included, of which 3,443 were identified with moderate to severe anxiety symptoms. Between-study heterogeneity was high (
I
2
=98.8%) with the reported prevalence ranging from 9.6% to 69.17%, and the pooled prevalence was 38.08% (95% confidence interval: 28.82–47.81%) by a random-effects model. Meta-regression analyses indicated that publication year (
β
= −0.014) was significant moderators contributing 16.11% to the heterogeneity. Subgroup analyses indicated that studies using the anxiety subscale of Brief Symptom Inventory to assess anxiety were homogenous (
I
2
=0.0). Furthermore, the pooled prevalence of moderate to severe anxiety symptoms varied significantly by geographic region, instrument used to assess anxiety, methodological quality, sex, education level, a history of previous MI and hypercholesterolemia. Additionally, the results of Egger’s linear test (
t
= −0.630) and Begg’s rank test (
z
= −0.190) indicated no evidence of publication bias, and the sensitivity of the pooled results was low. Nearly two fifth of MI patients suffered from moderate to severe anxiety symptoms, which emphasizes the importance of early identification of anxiety symptoms after MI, as well as the need of implementing psychological interventions for those with elevated anxiety symptoms.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>34013389</pmid><doi>10.1007/s11126-021-09921-y</doi><tpages>20</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Psychiatric quarterly, 2022-03, Vol.93 (1), p.161-180 |
| issn | 0033-2720 1573-6709 |
| language | eng |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); SpringerLink Journals - AutoHoldings |
| subjects | Anxiety Anxiety - epidemiology Anxiety Disorders Bias Heart attacks Heterogeneity Humans Hypercholesterolemia Medicine Medicine & Public Health Meta-analysis Moderators Myocardial infarction Myocardial Infarction - epidemiology Prevalence Psychiatry Public Health Review Article Risk Assessment Robustness Severity Sociology |
| title | Prevalence of Moderate to Severe Anxiety Symptoms among Patients with Myocardial Infarction: a Meta-Analysis |
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