CHO/LY‐B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid‐restricted cell membranes

Sphingolipids (SL) are ubiquitous in mammalian cell membranes, yet there is little data on the behavior of cells under SL‐restriction conditions. LY‐B cells derive from a CHO linein whichserine palmitoyl transferase (SPT), thus de novo SL synthesis, is suppressed, while maintaining the capacity of t...

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Veröffentlicht in:	The FASEB journal 2021-06, Vol.35 (6), p.e21657-n/a
Hauptverfasser:	Monasterio, Bingen G., Jiménez‐Rojo, Noemi, García‐Arribas, Aritz B., Riezman, Howard, Goñi, Félix M., Alonso, Alicia
Format:	Artikel
Sprache:	eng
Schlagworte:	AFM CHO Laurdan lipidomics LY‐B mass‐spectroscopy membrane fluidity plasma membrane sphingolipids sphingomyelin
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