The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population
The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3 and 22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of deb...
Gespeichert in:
| Veröffentlicht in: | Brain Structure and Function 2021-07, Vol.226 (6), p.1871-1878 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1878 |
|---|---|
| container_issue | 6 |
| container_start_page | 1871 |
| container_title | Brain Structure and Function |
| container_volume | 226 |
| creator | Miró-Padilla, Anna Adrián-Ventura, Jesús Costumero, Víctor Palomar-García, María-Ángeles Villar-Rodríguez, Esteban Marin-Marin, Lidón Aguirre, Naiara Bueichekú, Elisenda |
| description | The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3 and 22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of debate. Despite the existence of these demographic figures, it remains unclear how this distinctive feature affects healthy people, or what specific anatomic profile is related to the presence or absence of the AI. The aim of this study was to investigate whole-brain gray matter (GM) volumetric differences depending on the presence or absence of the AI. A total of 240 healthy adult volunteers completed one MRI scanning session. After the AI assessment, the data from 110 participants were included in the final sample, of which 12.9% of the participants (
n
= 31) presented complete AI absence vs. 32.9% of participants (
n
= 79) who presented complete AI presence. Then, whole-brain group comparison analysis revealed that the absent AI brain, compared to the present AI brain, was associated with lower GM volume in the premotor cortex, inferior frontal gyrus, and anterior temporal cortex. Interestingly, neuroscience research has linked emotional and cognitive control brain processing to the latter two regions. The importance of these findings lies in providing a neuroanatomical profile for the absent AI brain in healthy human adults. |
| doi_str_mv | 10.1007/s00429-021-02297-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2529914458</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2540614068</sourcerecordid><originalsourceid>FETCH-LOGICAL-c419t-ef54a3dc4bf49f97f249cac774ec35af83e0273a6ef8c9d9fe945e72db033da33</originalsourceid><addsrcrecordid>eNp9kUlrHDEQhUWIidc_kIMR5JJL29p60dGYLAaDL_ZZ1KhL6R5rWhMtB__7aDwTB3zIoZAoffVKvEfIZ86uOGP9dWJMCd0wwWsJ3TfdB3LCh042ouv4x7d7K4_JaUprxlo9cP2JHEvFuFKMnRD_OCGFccI0BzovGWOewMNmtkAhUaALlhhggRx2PU83EJ8x0uBoyrHYXGJtjrNzGHGxmKoInRB8nl6qbvGZbsO2eMhzWM7JkQOf8OJwnpGn798eb3829w8_7m5v7huruM4NulaBHK1aOaWd7p1Q2oLte4VWtuAGiUz0Ejp0g9WjdqhVi70YV0zKEaQ8I1_3utsYfhdM2WzmZNF7WDCUZEQrtK4GtENFv7xD16HEpf6uUop1vNaOEnvKxpBSRGe2ca5OvBjOzC4Ls8_C1CzMaxamq0OXB-my2uD4NvLX_ArIPZDq0_IL47_d_5H9A_Xrlng</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2540614068</pqid></control><display><type>article</type><title>The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population</title><source>SpringerLink Journals</source><creator>Miró-Padilla, Anna ; Adrián-Ventura, Jesús ; Costumero, Víctor ; Palomar-García, María-Ángeles ; Villar-Rodríguez, Esteban ; Marin-Marin, Lidón ; Aguirre, Naiara ; Bueichekú, Elisenda</creator><creatorcontrib>Miró-Padilla, Anna ; Adrián-Ventura, Jesús ; Costumero, Víctor ; Palomar-García, María-Ángeles ; Villar-Rodríguez, Esteban ; Marin-Marin, Lidón ; Aguirre, Naiara ; Bueichekú, Elisenda</creatorcontrib><description>The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3 and 22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of debate. Despite the existence of these demographic figures, it remains unclear how this distinctive feature affects healthy people, or what specific anatomic profile is related to the presence or absence of the AI. The aim of this study was to investigate whole-brain gray matter (GM) volumetric differences depending on the presence or absence of the AI. A total of 240 healthy adult volunteers completed one MRI scanning session. After the AI assessment, the data from 110 participants were included in the final sample, of which 12.9% of the participants (
n
= 31) presented complete AI absence vs. 32.9% of participants (
n
= 79) who presented complete AI presence. Then, whole-brain group comparison analysis revealed that the absent AI brain, compared to the present AI brain, was associated with lower GM volume in the premotor cortex, inferior frontal gyrus, and anterior temporal cortex. Interestingly, neuroscience research has linked emotional and cognitive control brain processing to the latter two regions. The importance of these findings lies in providing a neuroanatomical profile for the absent AI brain in healthy human adults.</description><identifier>ISSN: 1863-2653</identifier><identifier>EISSN: 1863-2661</identifier><identifier>EISSN: 0340-2061</identifier><identifier>DOI: 10.1007/s00429-021-02297-6</identifier><identifier>PMID: 34014400</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Anatomy ; Biomedical and Life Sciences ; Biomedicine ; Brain architecture ; Cell Biology ; Cognitive ability ; Cortex (frontal) ; Cortex (premotor) ; Cortex (temporal) ; Frontal gyrus ; Information processing ; Magnetic resonance imaging ; Nervous system ; Neurology ; Neurosciences ; Original Article ; Sex differences ; Substantia grisea ; Thalamus</subject><ispartof>Brain Structure and Function, 2021-07, Vol.226 (6), p.1871-1878</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-ef54a3dc4bf49f97f249cac774ec35af83e0273a6ef8c9d9fe945e72db033da33</citedby><cites>FETCH-LOGICAL-c419t-ef54a3dc4bf49f97f249cac774ec35af83e0273a6ef8c9d9fe945e72db033da33</cites><orcidid>0000-0003-4745-9612 ; 0000-0002-6004-7439 ; 0000-0002-3059-9806 ; 0000-0003-2036-762X ; 0000-0001-7222-3631 ; 0000-0002-8743-5239 ; 0000-0002-0912-5139 ; 0000-0001-9691-3776</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00429-021-02297-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00429-021-02297-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34014400$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miró-Padilla, Anna</creatorcontrib><creatorcontrib>Adrián-Ventura, Jesús</creatorcontrib><creatorcontrib>Costumero, Víctor</creatorcontrib><creatorcontrib>Palomar-García, María-Ángeles</creatorcontrib><creatorcontrib>Villar-Rodríguez, Esteban</creatorcontrib><creatorcontrib>Marin-Marin, Lidón</creatorcontrib><creatorcontrib>Aguirre, Naiara</creatorcontrib><creatorcontrib>Bueichekú, Elisenda</creatorcontrib><title>The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population</title><title>Brain Structure and Function</title><addtitle>Brain Struct Funct</addtitle><addtitle>Brain Struct Funct</addtitle><description>The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3 and 22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of debate. Despite the existence of these demographic figures, it remains unclear how this distinctive feature affects healthy people, or what specific anatomic profile is related to the presence or absence of the AI. The aim of this study was to investigate whole-brain gray matter (GM) volumetric differences depending on the presence or absence of the AI. A total of 240 healthy adult volunteers completed one MRI scanning session. After the AI assessment, the data from 110 participants were included in the final sample, of which 12.9% of the participants (
n
= 31) presented complete AI absence vs. 32.9% of participants (
n
= 79) who presented complete AI presence. Then, whole-brain group comparison analysis revealed that the absent AI brain, compared to the present AI brain, was associated with lower GM volume in the premotor cortex, inferior frontal gyrus, and anterior temporal cortex. Interestingly, neuroscience research has linked emotional and cognitive control brain processing to the latter two regions. The importance of these findings lies in providing a neuroanatomical profile for the absent AI brain in healthy human adults.</description><subject>Anatomy</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Brain architecture</subject><subject>Cell Biology</subject><subject>Cognitive ability</subject><subject>Cortex (frontal)</subject><subject>Cortex (premotor)</subject><subject>Cortex (temporal)</subject><subject>Frontal gyrus</subject><subject>Information processing</subject><subject>Magnetic resonance imaging</subject><subject>Nervous system</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Original Article</subject><subject>Sex differences</subject><subject>Substantia grisea</subject><subject>Thalamus</subject><issn>1863-2653</issn><issn>1863-2661</issn><issn>0340-2061</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUlrHDEQhUWIidc_kIMR5JJL29p60dGYLAaDL_ZZ1KhL6R5rWhMtB__7aDwTB3zIoZAoffVKvEfIZ86uOGP9dWJMCd0wwWsJ3TfdB3LCh042ouv4x7d7K4_JaUprxlo9cP2JHEvFuFKMnRD_OCGFccI0BzovGWOewMNmtkAhUaALlhhggRx2PU83EJ8x0uBoyrHYXGJtjrNzGHGxmKoInRB8nl6qbvGZbsO2eMhzWM7JkQOf8OJwnpGn798eb3829w8_7m5v7huruM4NulaBHK1aOaWd7p1Q2oLte4VWtuAGiUz0Ejp0g9WjdqhVi70YV0zKEaQ8I1_3utsYfhdM2WzmZNF7WDCUZEQrtK4GtENFv7xD16HEpf6uUop1vNaOEnvKxpBSRGe2ca5OvBjOzC4Ls8_C1CzMaxamq0OXB-my2uD4NvLX_ArIPZDq0_IL47_d_5H9A_Xrlng</recordid><startdate>20210701</startdate><enddate>20210701</enddate><creator>Miró-Padilla, Anna</creator><creator>Adrián-Ventura, Jesús</creator><creator>Costumero, Víctor</creator><creator>Palomar-García, María-Ángeles</creator><creator>Villar-Rodríguez, Esteban</creator><creator>Marin-Marin, Lidón</creator><creator>Aguirre, Naiara</creator><creator>Bueichekú, Elisenda</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4745-9612</orcidid><orcidid>https://orcid.org/0000-0002-6004-7439</orcidid><orcidid>https://orcid.org/0000-0002-3059-9806</orcidid><orcidid>https://orcid.org/0000-0003-2036-762X</orcidid><orcidid>https://orcid.org/0000-0001-7222-3631</orcidid><orcidid>https://orcid.org/0000-0002-8743-5239</orcidid><orcidid>https://orcid.org/0000-0002-0912-5139</orcidid><orcidid>https://orcid.org/0000-0001-9691-3776</orcidid></search><sort><creationdate>20210701</creationdate><title>The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population</title><author>Miró-Padilla, Anna ; Adrián-Ventura, Jesús ; Costumero, Víctor ; Palomar-García, María-Ángeles ; Villar-Rodríguez, Esteban ; Marin-Marin, Lidón ; Aguirre, Naiara ; Bueichekú, Elisenda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-ef54a3dc4bf49f97f249cac774ec35af83e0273a6ef8c9d9fe945e72db033da33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anatomy</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Brain architecture</topic><topic>Cell Biology</topic><topic>Cognitive ability</topic><topic>Cortex (frontal)</topic><topic>Cortex (premotor)</topic><topic>Cortex (temporal)</topic><topic>Frontal gyrus</topic><topic>Information processing</topic><topic>Magnetic resonance imaging</topic><topic>Nervous system</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Original Article</topic><topic>Sex differences</topic><topic>Substantia grisea</topic><topic>Thalamus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miró-Padilla, Anna</creatorcontrib><creatorcontrib>Adrián-Ventura, Jesús</creatorcontrib><creatorcontrib>Costumero, Víctor</creatorcontrib><creatorcontrib>Palomar-García, María-Ángeles</creatorcontrib><creatorcontrib>Villar-Rodríguez, Esteban</creatorcontrib><creatorcontrib>Marin-Marin, Lidón</creatorcontrib><creatorcontrib>Aguirre, Naiara</creatorcontrib><creatorcontrib>Bueichekú, Elisenda</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Brain Structure and Function</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miró-Padilla, Anna</au><au>Adrián-Ventura, Jesús</au><au>Costumero, Víctor</au><au>Palomar-García, María-Ángeles</au><au>Villar-Rodríguez, Esteban</au><au>Marin-Marin, Lidón</au><au>Aguirre, Naiara</au><au>Bueichekú, Elisenda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population</atitle><jtitle>Brain Structure and Function</jtitle><stitle>Brain Struct Funct</stitle><addtitle>Brain Struct Funct</addtitle><date>2021-07-01</date><risdate>2021</risdate><volume>226</volume><issue>6</issue><spage>1871</spage><epage>1878</epage><pages>1871-1878</pages><issn>1863-2653</issn><eissn>1863-2661</eissn><eissn>0340-2061</eissn><abstract>The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3 and 22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of debate. Despite the existence of these demographic figures, it remains unclear how this distinctive feature affects healthy people, or what specific anatomic profile is related to the presence or absence of the AI. The aim of this study was to investigate whole-brain gray matter (GM) volumetric differences depending on the presence or absence of the AI. A total of 240 healthy adult volunteers completed one MRI scanning session. After the AI assessment, the data from 110 participants were included in the final sample, of which 12.9% of the participants (
n
= 31) presented complete AI absence vs. 32.9% of participants (
n
= 79) who presented complete AI presence. Then, whole-brain group comparison analysis revealed that the absent AI brain, compared to the present AI brain, was associated with lower GM volume in the premotor cortex, inferior frontal gyrus, and anterior temporal cortex. Interestingly, neuroscience research has linked emotional and cognitive control brain processing to the latter two regions. The importance of these findings lies in providing a neuroanatomical profile for the absent AI brain in healthy human adults.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34014400</pmid><doi>10.1007/s00429-021-02297-6</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-4745-9612</orcidid><orcidid>https://orcid.org/0000-0002-6004-7439</orcidid><orcidid>https://orcid.org/0000-0002-3059-9806</orcidid><orcidid>https://orcid.org/0000-0003-2036-762X</orcidid><orcidid>https://orcid.org/0000-0001-7222-3631</orcidid><orcidid>https://orcid.org/0000-0002-8743-5239</orcidid><orcidid>https://orcid.org/0000-0002-0912-5139</orcidid><orcidid>https://orcid.org/0000-0001-9691-3776</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1863-2653 |
| ispartof | Brain Structure and Function, 2021-07, Vol.226 (6), p.1871-1878 |
| issn | 1863-2653 1863-2661 0340-2061 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2529914458 |
| source | SpringerLink Journals |
| subjects | Anatomy Biomedical and Life Sciences Biomedicine Brain architecture Cell Biology Cognitive ability Cortex (frontal) Cortex (premotor) Cortex (temporal) Frontal gyrus Information processing Magnetic resonance imaging Nervous system Neurology Neurosciences Original Article Sex differences Substantia grisea Thalamus |
| title | The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T03%3A50%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20adhesio%20interthalamica%20as%20a%20neuroanatomical%20marker%20of%20structural%20differences%20in%20healthy%20adult%20population&rft.jtitle=Brain%20Structure%20and%20Function&rft.au=Mir%C3%B3-Padilla,%20Anna&rft.date=2021-07-01&rft.volume=226&rft.issue=6&rft.spage=1871&rft.epage=1878&rft.pages=1871-1878&rft.issn=1863-2653&rft.eissn=1863-2661&rft_id=info:doi/10.1007/s00429-021-02297-6&rft_dat=%3Cproquest_cross%3E2540614068%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2540614068&rft_id=info:pmid/34014400&rfr_iscdi=true |