A comprehensive assessment of patient experience and disease-related awareness in multiple sclerosis: A questionnaire-based nation-wide survey in Turkey
•The average time was 1.2 years for diagnosis and 2.5 months for onset of treatment.•Faster diagnosis was more likely in ophthalmology admissions.•Onset of treatment after diagnosis was more likely in neurology admissions.•Awareness on manifestations of MS should be improved to prevent delay in diag...
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Veröffentlicht in: | Multiple sclerosis and related disorders 2021-07, Vol.52, p.103005-103005, Article 103005 |
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creator | Demir, Serkan Tutuncu, Melih Uzunkopru, Cihat Gumus, Haluk Sen, Sedat Gunduz, Tuncay Dogan, Ipek Gungor Cinar, Bilge Piri Incirli, Sila Usar Tutuncu, Mesude Mavi, Kamil Yuksel, Suha Togrol, Rifat Erdem Kocaman, Ayse Sagduyu Siva, Aksel |
description | •The average time was 1.2 years for diagnosis and 2.5 months for onset of treatment.•Faster diagnosis was more likely in ophthalmology admissions.•Onset of treatment after diagnosis was more likely in neurology admissions.•Awareness on manifestations of MS should be improved to prevent delay in diagnosis.
Background: Comprehensive assessment of multiple sclerosis (MS) patients in terms of patient profile, clinical and disease-related factors has great epidemiological value. This study aimed to evaluate patient experience and disease-related awareness in MS patients through a nation-wide survey in Turkey
Methods: A total of 1379 MS patients participated in this cross-sectional questionnaire survey conducted between November 2018 and December 2018. The online questionnaire form included items on sociodemographic, disease-related, first-admission, treatment and follow up characteristics as well as the disability status.
Results: Patients were diagnosed at median 28.0 years of age, while the average time from admission to diagnosis and time from diagnosis to treatment were 1.2 years and 2.5 months, respectively. Neurology (45.4%) and ophthalmology (23.3%) were the most common clinics for the first admission, while numbness-weakness in lower and upper extremities (37.6%) and double vision-visual problems (30.6%) were the most common symptoms on initial admission. Treatment was initiated after the diagnosis in 1213(88.0%) patients, while 166 (12.0%) patients were treatment-naïve. Treatment discontinuation, treatment switch and use of alternative treatment methods were reported by 31.3%, 49.3% and 22.8% of patients, respectively. The ophthalmology admissions (with double vision or visual problems) were associated with the shortest time from presentation to diagnosis as compared with neurosurgery and internal medicine admissions (median 1.0 vs. 3.0 and 4.0 months, p |
doi_str_mv | 10.1016/j.msard.2021.103005 |
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fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2528818188</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S2211034821002728</els_id><sourcerecordid>2528818188</sourcerecordid><originalsourceid>FETCH-LOGICAL-c359t-f07fe94cda7cb92befa4ed62a9bb6551771a0b6451ed5412d3d8f31eb37c681f3</originalsourceid><addsrcrecordid>eNp9kU1u2zAQhYmiQWI4OUGAgstu5PBHlOQCXRhB2xQwkE2yJihyhNKVKJUj2fVNctxQdpplyQWHg-9xOPMIueVsxRkv7narDk10K8EETxnJmPpAFkJwnjGpio_vcV5dkRvEHUurUDwv-CW5kvl8q8SCvGyo7bshwi8I6PdADSIgdhBG2jd0MKOfQ_g7QEyRTUBw1HkEg5BFaM0IjpqDiRCSjvpAu6kd_dACRdtC7NHjF7qhfybA0fchGB8hq5Pa0WDmTHbwLsFT3MNx1j9N8Tccr8lFY1qEm7dzSZ6_f3u6f8i2jz9-3m-2mZVqPWYNKxtY59aZ0tZrUUNjcnCFMOu6LpTiZckNq4tccXAq58JJVzWSQy1LW1S8kUvy-fzuEPvTH3Xn0ULbmgD9hFooUVU87Sqh8oza1BVGaPQQfWfiUXOmZ1f0Tp9c0bMr-uxKUn16KzDVHbh3zT8PEvD1DEBqc-8harSnUbs0KTtq1_v_FngFhtGiuQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2528818188</pqid></control><display><type>article</type><title>A comprehensive assessment of patient experience and disease-related awareness in multiple sclerosis: A questionnaire-based nation-wide survey in Turkey</title><source>Alma/SFX Local Collection</source><creator>Demir, Serkan ; Tutuncu, Melih ; Uzunkopru, Cihat ; Gumus, Haluk ; Sen, Sedat ; Gunduz, Tuncay ; Dogan, Ipek Gungor ; Cinar, Bilge Piri ; Incirli, Sila Usar ; Tutuncu, Mesude ; Mavi, Kamil ; Yuksel, Suha ; Togrol, Rifat Erdem ; Kocaman, Ayse Sagduyu ; Siva, Aksel</creator><creatorcontrib>Demir, Serkan ; Tutuncu, Melih ; Uzunkopru, Cihat ; Gumus, Haluk ; Sen, Sedat ; Gunduz, Tuncay ; Dogan, Ipek Gungor ; Cinar, Bilge Piri ; Incirli, Sila Usar ; Tutuncu, Mesude ; Mavi, Kamil ; Yuksel, Suha ; Togrol, Rifat Erdem ; Kocaman, Ayse Sagduyu ; Siva, Aksel</creatorcontrib><description>•The average time was 1.2 years for diagnosis and 2.5 months for onset of treatment.•Faster diagnosis was more likely in ophthalmology admissions.•Onset of treatment after diagnosis was more likely in neurology admissions.•Awareness on manifestations of MS should be improved to prevent delay in diagnosis.
Background: Comprehensive assessment of multiple sclerosis (MS) patients in terms of patient profile, clinical and disease-related factors has great epidemiological value. This study aimed to evaluate patient experience and disease-related awareness in MS patients through a nation-wide survey in Turkey
Methods: A total of 1379 MS patients participated in this cross-sectional questionnaire survey conducted between November 2018 and December 2018. The online questionnaire form included items on sociodemographic, disease-related, first-admission, treatment and follow up characteristics as well as the disability status.
Results: Patients were diagnosed at median 28.0 years of age, while the average time from admission to diagnosis and time from diagnosis to treatment were 1.2 years and 2.5 months, respectively. Neurology (45.4%) and ophthalmology (23.3%) were the most common clinics for the first admission, while numbness-weakness in lower and upper extremities (37.6%) and double vision-visual problems (30.6%) were the most common symptoms on initial admission. Treatment was initiated after the diagnosis in 1213(88.0%) patients, while 166 (12.0%) patients were treatment-naïve. Treatment discontinuation, treatment switch and use of alternative treatment methods were reported by 31.3%, 49.3% and 22.8% of patients, respectively. The ophthalmology admissions (with double vision or visual problems) were associated with the shortest time from presentation to diagnosis as compared with neurosurgery and internal medicine admissions (median 1.0 vs. 3.0 and 4.0 months, p<0.001). The neurology admissions (with numbness-weakness in extremities) were associated with more prompt (median 0.3 vs. 0.5 months, p=0.032) and more frequent onset of treatment after diagnosis (64.5% vs. 2.2% to 15.2%, p<0.001). Time from presentation to diagnosis was longer in patients aged >50 years (median 6.0 months vs. 2.0 months, p<0.001), in patients using alternative medicine (median 3.0 months vs. 1 month, p=0.001) and in patients admitted to a non-MS-center (median 3.0 months vs. 2.0 months, p=0.002). Median (min-max) age at diagnosis was significantly lower in patients with vs. without treatment discontinuation for any reason (26.0(10-56) vs. 29.0(3-60) years, p<0.001) and treatment switching (27.0(5-93) vs. 30.0(3-60) years, p<0.001).
Conclusions: In conclusion, our findings revealed higher likelihood of earlier diagnosis and earlier treatment in patients admitted to an MS-center and in those presenting with ocular problems and sensory-motor deficits, respectively. Our findings also emphasize the association of older patient age with higher likelihood of diagnostic delay, and increased likelihood of treatment discontinuation for any reason and/or treatment switching in case of older patient age, younger age at diagnosis and diagnostic delay. In this regard, our findings highlight the need for improved awareness among patients as well as clinicians on initial manifestations of MS to enable admission or referral to an MS-center and to prevent delay in diagnosis, particularly for onset symptoms other than ocular or sensory-motor characteristics.</description><identifier>ISSN: 2211-0348</identifier><identifier>EISSN: 2211-0356</identifier><identifier>DOI: 10.1016/j.msard.2021.103005</identifier><identifier>PMID: 34000682</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Diagnostic delay ; First-admission specialties ; Multiple sclerosis ; Patient profile ; Treatment</subject><ispartof>Multiple sclerosis and related disorders, 2021-07, Vol.52, p.103005-103005, Article 103005</ispartof><rights>2021</rights><rights>Copyright © 2021. Published by Elsevier B.V.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-f07fe94cda7cb92befa4ed62a9bb6551771a0b6451ed5412d3d8f31eb37c681f3</citedby><cites>FETCH-LOGICAL-c359t-f07fe94cda7cb92befa4ed62a9bb6551771a0b6451ed5412d3d8f31eb37c681f3</cites><orcidid>0000-0001-7689-7131 ; 0000-0003-4395-5141 ; 0000-0002-5621-9453 ; 0000-0002-8340-6641 ; 0000-0003-4241-0908 ; 0000-0002-7907-5472</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34000682$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Demir, Serkan</creatorcontrib><creatorcontrib>Tutuncu, Melih</creatorcontrib><creatorcontrib>Uzunkopru, Cihat</creatorcontrib><creatorcontrib>Gumus, Haluk</creatorcontrib><creatorcontrib>Sen, Sedat</creatorcontrib><creatorcontrib>Gunduz, Tuncay</creatorcontrib><creatorcontrib>Dogan, Ipek Gungor</creatorcontrib><creatorcontrib>Cinar, Bilge Piri</creatorcontrib><creatorcontrib>Incirli, Sila Usar</creatorcontrib><creatorcontrib>Tutuncu, Mesude</creatorcontrib><creatorcontrib>Mavi, Kamil</creatorcontrib><creatorcontrib>Yuksel, Suha</creatorcontrib><creatorcontrib>Togrol, Rifat Erdem</creatorcontrib><creatorcontrib>Kocaman, Ayse Sagduyu</creatorcontrib><creatorcontrib>Siva, Aksel</creatorcontrib><title>A comprehensive assessment of patient experience and disease-related awareness in multiple sclerosis: A questionnaire-based nation-wide survey in Turkey</title><title>Multiple sclerosis and related disorders</title><addtitle>Mult Scler Relat Disord</addtitle><description>•The average time was 1.2 years for diagnosis and 2.5 months for onset of treatment.•Faster diagnosis was more likely in ophthalmology admissions.•Onset of treatment after diagnosis was more likely in neurology admissions.•Awareness on manifestations of MS should be improved to prevent delay in diagnosis.
Background: Comprehensive assessment of multiple sclerosis (MS) patients in terms of patient profile, clinical and disease-related factors has great epidemiological value. This study aimed to evaluate patient experience and disease-related awareness in MS patients through a nation-wide survey in Turkey
Methods: A total of 1379 MS patients participated in this cross-sectional questionnaire survey conducted between November 2018 and December 2018. The online questionnaire form included items on sociodemographic, disease-related, first-admission, treatment and follow up characteristics as well as the disability status.
Results: Patients were diagnosed at median 28.0 years of age, while the average time from admission to diagnosis and time from diagnosis to treatment were 1.2 years and 2.5 months, respectively. Neurology (45.4%) and ophthalmology (23.3%) were the most common clinics for the first admission, while numbness-weakness in lower and upper extremities (37.6%) and double vision-visual problems (30.6%) were the most common symptoms on initial admission. Treatment was initiated after the diagnosis in 1213(88.0%) patients, while 166 (12.0%) patients were treatment-naïve. Treatment discontinuation, treatment switch and use of alternative treatment methods were reported by 31.3%, 49.3% and 22.8% of patients, respectively. The ophthalmology admissions (with double vision or visual problems) were associated with the shortest time from presentation to diagnosis as compared with neurosurgery and internal medicine admissions (median 1.0 vs. 3.0 and 4.0 months, p<0.001). The neurology admissions (with numbness-weakness in extremities) were associated with more prompt (median 0.3 vs. 0.5 months, p=0.032) and more frequent onset of treatment after diagnosis (64.5% vs. 2.2% to 15.2%, p<0.001). Time from presentation to diagnosis was longer in patients aged >50 years (median 6.0 months vs. 2.0 months, p<0.001), in patients using alternative medicine (median 3.0 months vs. 1 month, p=0.001) and in patients admitted to a non-MS-center (median 3.0 months vs. 2.0 months, p=0.002). Median (min-max) age at diagnosis was significantly lower in patients with vs. without treatment discontinuation for any reason (26.0(10-56) vs. 29.0(3-60) years, p<0.001) and treatment switching (27.0(5-93) vs. 30.0(3-60) years, p<0.001).
Conclusions: In conclusion, our findings revealed higher likelihood of earlier diagnosis and earlier treatment in patients admitted to an MS-center and in those presenting with ocular problems and sensory-motor deficits, respectively. Our findings also emphasize the association of older patient age with higher likelihood of diagnostic delay, and increased likelihood of treatment discontinuation for any reason and/or treatment switching in case of older patient age, younger age at diagnosis and diagnostic delay. In this regard, our findings highlight the need for improved awareness among patients as well as clinicians on initial manifestations of MS to enable admission or referral to an MS-center and to prevent delay in diagnosis, particularly for onset symptoms other than ocular or sensory-motor characteristics.</description><subject>Diagnostic delay</subject><subject>First-admission specialties</subject><subject>Multiple sclerosis</subject><subject>Patient profile</subject><subject>Treatment</subject><issn>2211-0348</issn><issn>2211-0356</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kU1u2zAQhYmiQWI4OUGAgstu5PBHlOQCXRhB2xQwkE2yJihyhNKVKJUj2fVNctxQdpplyQWHg-9xOPMIueVsxRkv7narDk10K8EETxnJmPpAFkJwnjGpio_vcV5dkRvEHUurUDwv-CW5kvl8q8SCvGyo7bshwi8I6PdADSIgdhBG2jd0MKOfQ_g7QEyRTUBw1HkEg5BFaM0IjpqDiRCSjvpAu6kd_dACRdtC7NHjF7qhfybA0fchGB8hq5Pa0WDmTHbwLsFT3MNx1j9N8Tccr8lFY1qEm7dzSZ6_f3u6f8i2jz9-3m-2mZVqPWYNKxtY59aZ0tZrUUNjcnCFMOu6LpTiZckNq4tccXAq58JJVzWSQy1LW1S8kUvy-fzuEPvTH3Xn0ULbmgD9hFooUVU87Sqh8oza1BVGaPQQfWfiUXOmZ1f0Tp9c0bMr-uxKUn16KzDVHbh3zT8PEvD1DEBqc-8harSnUbs0KTtq1_v_FngFhtGiuQ</recordid><startdate>20210701</startdate><enddate>20210701</enddate><creator>Demir, Serkan</creator><creator>Tutuncu, Melih</creator><creator>Uzunkopru, Cihat</creator><creator>Gumus, Haluk</creator><creator>Sen, Sedat</creator><creator>Gunduz, Tuncay</creator><creator>Dogan, Ipek Gungor</creator><creator>Cinar, Bilge Piri</creator><creator>Incirli, Sila Usar</creator><creator>Tutuncu, Mesude</creator><creator>Mavi, Kamil</creator><creator>Yuksel, Suha</creator><creator>Togrol, Rifat Erdem</creator><creator>Kocaman, Ayse Sagduyu</creator><creator>Siva, Aksel</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7689-7131</orcidid><orcidid>https://orcid.org/0000-0003-4395-5141</orcidid><orcidid>https://orcid.org/0000-0002-5621-9453</orcidid><orcidid>https://orcid.org/0000-0002-8340-6641</orcidid><orcidid>https://orcid.org/0000-0003-4241-0908</orcidid><orcidid>https://orcid.org/0000-0002-7907-5472</orcidid></search><sort><creationdate>20210701</creationdate><title>A comprehensive assessment of patient experience and disease-related awareness in multiple sclerosis: A questionnaire-based nation-wide survey in Turkey</title><author>Demir, Serkan ; Tutuncu, Melih ; Uzunkopru, Cihat ; Gumus, Haluk ; Sen, Sedat ; Gunduz, Tuncay ; Dogan, Ipek Gungor ; Cinar, Bilge Piri ; Incirli, Sila Usar ; Tutuncu, Mesude ; Mavi, Kamil ; Yuksel, Suha ; Togrol, Rifat Erdem ; Kocaman, Ayse Sagduyu ; Siva, Aksel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-f07fe94cda7cb92befa4ed62a9bb6551771a0b6451ed5412d3d8f31eb37c681f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Diagnostic delay</topic><topic>First-admission specialties</topic><topic>Multiple sclerosis</topic><topic>Patient profile</topic><topic>Treatment</topic><toplevel>online_resources</toplevel><creatorcontrib>Demir, Serkan</creatorcontrib><creatorcontrib>Tutuncu, Melih</creatorcontrib><creatorcontrib>Uzunkopru, Cihat</creatorcontrib><creatorcontrib>Gumus, Haluk</creatorcontrib><creatorcontrib>Sen, Sedat</creatorcontrib><creatorcontrib>Gunduz, Tuncay</creatorcontrib><creatorcontrib>Dogan, Ipek Gungor</creatorcontrib><creatorcontrib>Cinar, Bilge Piri</creatorcontrib><creatorcontrib>Incirli, Sila Usar</creatorcontrib><creatorcontrib>Tutuncu, Mesude</creatorcontrib><creatorcontrib>Mavi, Kamil</creatorcontrib><creatorcontrib>Yuksel, Suha</creatorcontrib><creatorcontrib>Togrol, Rifat Erdem</creatorcontrib><creatorcontrib>Kocaman, Ayse Sagduyu</creatorcontrib><creatorcontrib>Siva, Aksel</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Multiple sclerosis and related disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Demir, Serkan</au><au>Tutuncu, Melih</au><au>Uzunkopru, Cihat</au><au>Gumus, Haluk</au><au>Sen, Sedat</au><au>Gunduz, Tuncay</au><au>Dogan, Ipek Gungor</au><au>Cinar, Bilge Piri</au><au>Incirli, Sila Usar</au><au>Tutuncu, Mesude</au><au>Mavi, Kamil</au><au>Yuksel, Suha</au><au>Togrol, Rifat Erdem</au><au>Kocaman, Ayse Sagduyu</au><au>Siva, Aksel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comprehensive assessment of patient experience and disease-related awareness in multiple sclerosis: A questionnaire-based nation-wide survey in Turkey</atitle><jtitle>Multiple sclerosis and related disorders</jtitle><addtitle>Mult Scler Relat Disord</addtitle><date>2021-07-01</date><risdate>2021</risdate><volume>52</volume><spage>103005</spage><epage>103005</epage><pages>103005-103005</pages><artnum>103005</artnum><issn>2211-0348</issn><eissn>2211-0356</eissn><abstract>•The average time was 1.2 years for diagnosis and 2.5 months for onset of treatment.•Faster diagnosis was more likely in ophthalmology admissions.•Onset of treatment after diagnosis was more likely in neurology admissions.•Awareness on manifestations of MS should be improved to prevent delay in diagnosis.
Background: Comprehensive assessment of multiple sclerosis (MS) patients in terms of patient profile, clinical and disease-related factors has great epidemiological value. This study aimed to evaluate patient experience and disease-related awareness in MS patients through a nation-wide survey in Turkey
Methods: A total of 1379 MS patients participated in this cross-sectional questionnaire survey conducted between November 2018 and December 2018. The online questionnaire form included items on sociodemographic, disease-related, first-admission, treatment and follow up characteristics as well as the disability status.
Results: Patients were diagnosed at median 28.0 years of age, while the average time from admission to diagnosis and time from diagnosis to treatment were 1.2 years and 2.5 months, respectively. Neurology (45.4%) and ophthalmology (23.3%) were the most common clinics for the first admission, while numbness-weakness in lower and upper extremities (37.6%) and double vision-visual problems (30.6%) were the most common symptoms on initial admission. Treatment was initiated after the diagnosis in 1213(88.0%) patients, while 166 (12.0%) patients were treatment-naïve. Treatment discontinuation, treatment switch and use of alternative treatment methods were reported by 31.3%, 49.3% and 22.8% of patients, respectively. The ophthalmology admissions (with double vision or visual problems) were associated with the shortest time from presentation to diagnosis as compared with neurosurgery and internal medicine admissions (median 1.0 vs. 3.0 and 4.0 months, p<0.001). The neurology admissions (with numbness-weakness in extremities) were associated with more prompt (median 0.3 vs. 0.5 months, p=0.032) and more frequent onset of treatment after diagnosis (64.5% vs. 2.2% to 15.2%, p<0.001). Time from presentation to diagnosis was longer in patients aged >50 years (median 6.0 months vs. 2.0 months, p<0.001), in patients using alternative medicine (median 3.0 months vs. 1 month, p=0.001) and in patients admitted to a non-MS-center (median 3.0 months vs. 2.0 months, p=0.002). Median (min-max) age at diagnosis was significantly lower in patients with vs. without treatment discontinuation for any reason (26.0(10-56) vs. 29.0(3-60) years, p<0.001) and treatment switching (27.0(5-93) vs. 30.0(3-60) years, p<0.001).
Conclusions: In conclusion, our findings revealed higher likelihood of earlier diagnosis and earlier treatment in patients admitted to an MS-center and in those presenting with ocular problems and sensory-motor deficits, respectively. Our findings also emphasize the association of older patient age with higher likelihood of diagnostic delay, and increased likelihood of treatment discontinuation for any reason and/or treatment switching in case of older patient age, younger age at diagnosis and diagnostic delay. In this regard, our findings highlight the need for improved awareness among patients as well as clinicians on initial manifestations of MS to enable admission or referral to an MS-center and to prevent delay in diagnosis, particularly for onset symptoms other than ocular or sensory-motor characteristics.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>34000682</pmid><doi>10.1016/j.msard.2021.103005</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-7689-7131</orcidid><orcidid>https://orcid.org/0000-0003-4395-5141</orcidid><orcidid>https://orcid.org/0000-0002-5621-9453</orcidid><orcidid>https://orcid.org/0000-0002-8340-6641</orcidid><orcidid>https://orcid.org/0000-0003-4241-0908</orcidid><orcidid>https://orcid.org/0000-0002-7907-5472</orcidid></addata></record> |
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subjects | Diagnostic delay First-admission specialties Multiple sclerosis Patient profile Treatment |
title | A comprehensive assessment of patient experience and disease-related awareness in multiple sclerosis: A questionnaire-based nation-wide survey in Turkey |
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