Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery

There is an unmet need to develop strategies that allow site-specific delivery of short interfering RNA (siRNA) without any associated toxicity. To address this challenge, we have developed a novel siRNA delivery platform using chemically modified pluronic F108 as an amphiphilic polymer with a relea...

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Veröffentlicht in:	Biomaterials science 2021-06, Vol.9 (11), p.3939-3944
Hauptverfasser:	Kadekar, Sandeep, Nawale, Ganesh N, Rangasami, Vignesh K, Le Joncour, Vadim, Laakkonen, Pirjo, Hilborn, Jöns, Varghese, Oommen P, Oommen, Oommen P
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Colon Micelles Modular design Peptides Toxicity
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