Hi-C as a molecular rangefinder to examine genomic rearrangements

The mammalian genome is highly packed into the nucleus. Over the past decade, the development of Hi-C has contributed significantly to our understanding of the three-dimensional (3D) chromatin structure, uncovering the principles and functions of higher-order chromatin organizations. Recent studies...

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Veröffentlicht in:	Seminars in cell & developmental biology 2022-01, Vol.121, p.161-170
Hauptverfasser:	Kim, Kyukwang, Kim, Mooyoung, Kim, Yubin, Lee, Dongsung, Jung, Inkyung
Format:	Artikel
Sprache:	eng
Schlagworte:	3D chromatin structure Chromatin - metabolism Computational Biology - methods Genomics - methods Hi-C Humans Single-cell Hi-C Structural variations
Online-Zugang:	Volltext
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