Effectiveness of palonosetron versus granisetron in preventing chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis

Purpose Chemotherapy-induced nausea and vomiting (CINV) commonly occurs after chemotherapy, adversely affecting patients’ quality of life. Recently, studies have shown inconsistent antiemetic effects of two common 5-hydroxytryptamine 3 receptor antagonists, namely, palonosetron and granisetron. Ther...

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Veröffentlicht in:	European journal of clinical pharmacology 2021-11, Vol.77 (11), p.1597-1609
Hauptverfasser:	Hsu, Yu-Chen, Chen, Ching-Yao, Tam, Ka-Wai, Hsu, Chin-Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiemetics - therapeutic use Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Biomedical and Life Sciences Biomedicine Chemotherapy Clinical trials Constipation Granisetron - adverse effects Granisetron - therapeutic use Headache Humans Meta-analysis Nausea Nausea - chemically induced Nausea - drug therapy Palonosetron - adverse effects Palonosetron - therapeutic use Pharmacology/Toxicology Quality of Life Randomized Controlled Trials as Topic Review Serotonin Serotonin 5-HT3 Receptor Antagonists - therapeutic use Vomiting Vomiting - chemically induced Vomiting - drug therapy
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