Can T2-weighted Dixon fat-only images replace T1-weighted images in degenerative disc disease with Modic changes on lumbar spine MRI?
Objectives To evaluate the diagnostic performance and interobserver agreement of a magnetic resonance imaging (MRI) protocol that only includes sagittal T2-weighted Dixon fat and water images as an alternative to a standard protocol that includes both sagittal T1-weighted sequence and T2-weighted Di...
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Veröffentlicht in: | European radiology 2021-12, Vol.31 (12), p.9380-9389 |
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creator | Yang, Sisi Lassalle, Louis Mekki, Ahmed Appert, Gautier Rannou, François Nguyen, Christelle Lefèvre-Colau, Marie-Martine Mutschler, Céline Drapé, Jean-Luc Feydy, Antoine |
description | Objectives
To evaluate the diagnostic performance and interobserver agreement of a magnetic resonance imaging (MRI) protocol that only includes sagittal T2-weighted Dixon fat and water images as an alternative to a standard protocol that includes both sagittal T1-weighted sequence and T2-weighted Dixon water images as reference standard in lumbar degenerative disc disease with Modic changes.
Methods
From February 2017 to March 2019, 114 patients who underwent lumbar spine MRI for low back pain were included in this retrospective study. All MRI showed Modic changes at least at one vertebral level. Two radiologists read the standard protocol and 1 month later the alternative protocol. All MRI were assessed for Modic changes (types, location, extension) as well as structural changes (endplate defects, facet arthropathy, spinal stenosis, foraminal stenosis, Schmorl nodes, spondylolisthesis, disc bulges, and degeneration). Interobserver agreement was assessed, as well as diagnostic performance using the standard protocol as reference standard.
Results
Interobserver agreement was moderate to excellent (kappa ranging from 0.51 to 0.92). Diagnostic performance of the alternative protocol was good for detection of any Modic change (sensitivity = 100.00% [95% CI, 99.03–100.00]; specificity = 98.89% [95% CI, 98.02–99.44]), as well as for detection of each Modic subtype and structural variables (sensitivity respectively 100% and ranging from 88.43 to 99.75% ; specificity ranging respectively from 97.62 to 100% and 99.58 to 99.91% ).
Conclusions
Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images provide good diagnostic performance compared to T1-weighted images in lumbar degenerative disc disease with Modic changes, and could therefore allow for a shortened protocol.
Key Points
• Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images (in comparison to T1-weighted sequence) can provide good diagnostic performance in lumbar degenerative disc disease with Modic changes.
• Interobserver agreement of the alternative protocol including sagittal T2-weighted Dixon fat and water images was substantial to excellent for every studied variable except for facet arthropathy.
• A shortened MRI protocol including T2-weighted Dixon sequence without T1-weighted sequence could be proposed in this clinical setting. |
doi_str_mv | 10.1007/s00330-021-07946-2 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2528436624</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2528436624</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-ce671b185a5b3ee6390593946de1c1fca8548d4fa09af214c68af68ebdf029693</originalsourceid><addsrcrecordid>eNp9kctuEzEUhi1ERUPhBVggS2y6cevbeOxVhdIClVohobC2PJ4ziauJJ7VnenkA3huHpK3Eoht7cb7z-_h8CH1i9IRRWp9mSoWghHJGaG2kIvwNmjEpOGFUy7doRo3QpDZGHqL3Od9QSg2T9Tt0KIQxQnA9Q3_mLuIFJ_cQlqsRWnweHoaIOzeSIfaPOKzdEjJOsOmdB7xgL-S-FCJuYQkRkhvDHeA2ZL89wGXA92Fc4euhDR77lYtbvqT307pxCedNiICvf12efUAHneszfNzfR-j3t4vF_Ae5-vn9cv71inhRVyPxoGrWMF25qhEAShhaGVF-3gLzrPNOV1K3snPUuI4z6ZV2ndLQtB3lRhlxhI53uZs03E6QR7su00LfuwjDlC2vuJZCKS4L-uU_9GaYUizTFcoozSrBWaH4jvJpyDlBZzep7CU9WkbtVpLdSbJFkv0nyfLS9HkfPTVraJ9bnqwUQOyAXEplaenl7Vdi_wLaepxp</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2596815321</pqid></control><display><type>article</type><title>Can T2-weighted Dixon fat-only images replace T1-weighted images in degenerative disc disease with Modic changes on lumbar spine MRI?</title><source>SpringerLink Journals - AutoHoldings</source><creator>Yang, Sisi ; Lassalle, Louis ; Mekki, Ahmed ; Appert, Gautier ; Rannou, François ; Nguyen, Christelle ; Lefèvre-Colau, Marie-Martine ; Mutschler, Céline ; Drapé, Jean-Luc ; Feydy, Antoine</creator><creatorcontrib>Yang, Sisi ; Lassalle, Louis ; Mekki, Ahmed ; Appert, Gautier ; Rannou, François ; Nguyen, Christelle ; Lefèvre-Colau, Marie-Martine ; Mutschler, Céline ; Drapé, Jean-Luc ; Feydy, Antoine</creatorcontrib><description>Objectives
To evaluate the diagnostic performance and interobserver agreement of a magnetic resonance imaging (MRI) protocol that only includes sagittal T2-weighted Dixon fat and water images as an alternative to a standard protocol that includes both sagittal T1-weighted sequence and T2-weighted Dixon water images as reference standard in lumbar degenerative disc disease with Modic changes.
Methods
From February 2017 to March 2019, 114 patients who underwent lumbar spine MRI for low back pain were included in this retrospective study. All MRI showed Modic changes at least at one vertebral level. Two radiologists read the standard protocol and 1 month later the alternative protocol. All MRI were assessed for Modic changes (types, location, extension) as well as structural changes (endplate defects, facet arthropathy, spinal stenosis, foraminal stenosis, Schmorl nodes, spondylolisthesis, disc bulges, and degeneration). Interobserver agreement was assessed, as well as diagnostic performance using the standard protocol as reference standard.
Results
Interobserver agreement was moderate to excellent (kappa ranging from 0.51 to 0.92). Diagnostic performance of the alternative protocol was good for detection of any Modic change (sensitivity = 100.00% [95% CI, 99.03–100.00]; specificity = 98.89% [95% CI, 98.02–99.44]), as well as for detection of each Modic subtype and structural variables (sensitivity respectively 100% and ranging from 88.43 to 99.75% ; specificity ranging respectively from 97.62 to 100% and 99.58 to 99.91% ).
Conclusions
Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images provide good diagnostic performance compared to T1-weighted images in lumbar degenerative disc disease with Modic changes, and could therefore allow for a shortened protocol.
Key Points
• Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images (in comparison to T1-weighted sequence) can provide good diagnostic performance in lumbar degenerative disc disease with Modic changes.
• Interobserver agreement of the alternative protocol including sagittal T2-weighted Dixon fat and water images was substantial to excellent for every studied variable except for facet arthropathy.
• A shortened MRI protocol including T2-weighted Dixon sequence without T1-weighted sequence could be proposed in this clinical setting.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-021-07946-2</identifier><identifier>PMID: 33993328</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Degeneration ; Degenerative disc disease ; Diagnostic Radiology ; Diagnostic systems ; Imaging ; Internal Medicine ; Interventional Radiology ; Intervertebral discs ; Low back pain ; Magnetic resonance imaging ; Medical imaging ; Medicine ; Medicine & Public Health ; Musculoskeletal ; Neuroradiology ; Performance evaluation ; Radiology ; Sensitivity ; Spinal stenosis ; Spine ; Spine (lumbar) ; Spondylolisthesis ; Ultrasound ; Vertebrae</subject><ispartof>European radiology, 2021-12, Vol.31 (12), p.9380-9389</ispartof><rights>European Society of Radiology 2021</rights><rights>European Society of Radiology 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-ce671b185a5b3ee6390593946de1c1fca8548d4fa09af214c68af68ebdf029693</citedby><cites>FETCH-LOGICAL-c375t-ce671b185a5b3ee6390593946de1c1fca8548d4fa09af214c68af68ebdf029693</cites><orcidid>0000-0003-3498-9091</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-021-07946-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-021-07946-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33993328$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Sisi</creatorcontrib><creatorcontrib>Lassalle, Louis</creatorcontrib><creatorcontrib>Mekki, Ahmed</creatorcontrib><creatorcontrib>Appert, Gautier</creatorcontrib><creatorcontrib>Rannou, François</creatorcontrib><creatorcontrib>Nguyen, Christelle</creatorcontrib><creatorcontrib>Lefèvre-Colau, Marie-Martine</creatorcontrib><creatorcontrib>Mutschler, Céline</creatorcontrib><creatorcontrib>Drapé, Jean-Luc</creatorcontrib><creatorcontrib>Feydy, Antoine</creatorcontrib><title>Can T2-weighted Dixon fat-only images replace T1-weighted images in degenerative disc disease with Modic changes on lumbar spine MRI?</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
To evaluate the diagnostic performance and interobserver agreement of a magnetic resonance imaging (MRI) protocol that only includes sagittal T2-weighted Dixon fat and water images as an alternative to a standard protocol that includes both sagittal T1-weighted sequence and T2-weighted Dixon water images as reference standard in lumbar degenerative disc disease with Modic changes.
Methods
From February 2017 to March 2019, 114 patients who underwent lumbar spine MRI for low back pain were included in this retrospective study. All MRI showed Modic changes at least at one vertebral level. Two radiologists read the standard protocol and 1 month later the alternative protocol. All MRI were assessed for Modic changes (types, location, extension) as well as structural changes (endplate defects, facet arthropathy, spinal stenosis, foraminal stenosis, Schmorl nodes, spondylolisthesis, disc bulges, and degeneration). Interobserver agreement was assessed, as well as diagnostic performance using the standard protocol as reference standard.
Results
Interobserver agreement was moderate to excellent (kappa ranging from 0.51 to 0.92). Diagnostic performance of the alternative protocol was good for detection of any Modic change (sensitivity = 100.00% [95% CI, 99.03–100.00]; specificity = 98.89% [95% CI, 98.02–99.44]), as well as for detection of each Modic subtype and structural variables (sensitivity respectively 100% and ranging from 88.43 to 99.75% ; specificity ranging respectively from 97.62 to 100% and 99.58 to 99.91% ).
Conclusions
Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images provide good diagnostic performance compared to T1-weighted images in lumbar degenerative disc disease with Modic changes, and could therefore allow for a shortened protocol.
Key Points
• Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images (in comparison to T1-weighted sequence) can provide good diagnostic performance in lumbar degenerative disc disease with Modic changes.
• Interobserver agreement of the alternative protocol including sagittal T2-weighted Dixon fat and water images was substantial to excellent for every studied variable except for facet arthropathy.
• A shortened MRI protocol including T2-weighted Dixon sequence without T1-weighted sequence could be proposed in this clinical setting.</description><subject>Degeneration</subject><subject>Degenerative disc disease</subject><subject>Diagnostic Radiology</subject><subject>Diagnostic systems</subject><subject>Imaging</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Intervertebral discs</subject><subject>Low back pain</subject><subject>Magnetic resonance imaging</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Musculoskeletal</subject><subject>Neuroradiology</subject><subject>Performance evaluation</subject><subject>Radiology</subject><subject>Sensitivity</subject><subject>Spinal stenosis</subject><subject>Spine</subject><subject>Spine (lumbar)</subject><subject>Spondylolisthesis</subject><subject>Ultrasound</subject><subject>Vertebrae</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kctuEzEUhi1ERUPhBVggS2y6cevbeOxVhdIClVohobC2PJ4ziauJJ7VnenkA3huHpK3Eoht7cb7z-_h8CH1i9IRRWp9mSoWghHJGaG2kIvwNmjEpOGFUy7doRo3QpDZGHqL3Od9QSg2T9Tt0KIQxQnA9Q3_mLuIFJ_cQlqsRWnweHoaIOzeSIfaPOKzdEjJOsOmdB7xgL-S-FCJuYQkRkhvDHeA2ZL89wGXA92Fc4euhDR77lYtbvqT307pxCedNiICvf12efUAHneszfNzfR-j3t4vF_Ae5-vn9cv71inhRVyPxoGrWMF25qhEAShhaGVF-3gLzrPNOV1K3snPUuI4z6ZV2ndLQtB3lRhlxhI53uZs03E6QR7su00LfuwjDlC2vuJZCKS4L-uU_9GaYUizTFcoozSrBWaH4jvJpyDlBZzep7CU9WkbtVpLdSbJFkv0nyfLS9HkfPTVraJ9bnqwUQOyAXEplaenl7Vdi_wLaepxp</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Yang, Sisi</creator><creator>Lassalle, Louis</creator><creator>Mekki, Ahmed</creator><creator>Appert, Gautier</creator><creator>Rannou, François</creator><creator>Nguyen, Christelle</creator><creator>Lefèvre-Colau, Marie-Martine</creator><creator>Mutschler, Céline</creator><creator>Drapé, Jean-Luc</creator><creator>Feydy, Antoine</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3498-9091</orcidid></search><sort><creationdate>20211201</creationdate><title>Can T2-weighted Dixon fat-only images replace T1-weighted images in degenerative disc disease with Modic changes on lumbar spine MRI?</title><author>Yang, Sisi ; Lassalle, Louis ; Mekki, Ahmed ; Appert, Gautier ; Rannou, François ; Nguyen, Christelle ; Lefèvre-Colau, Marie-Martine ; Mutschler, Céline ; Drapé, Jean-Luc ; Feydy, Antoine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-ce671b185a5b3ee6390593946de1c1fca8548d4fa09af214c68af68ebdf029693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Degeneration</topic><topic>Degenerative disc disease</topic><topic>Diagnostic Radiology</topic><topic>Diagnostic systems</topic><topic>Imaging</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Intervertebral discs</topic><topic>Low back pain</topic><topic>Magnetic resonance imaging</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Musculoskeletal</topic><topic>Neuroradiology</topic><topic>Performance evaluation</topic><topic>Radiology</topic><topic>Sensitivity</topic><topic>Spinal stenosis</topic><topic>Spine</topic><topic>Spine (lumbar)</topic><topic>Spondylolisthesis</topic><topic>Ultrasound</topic><topic>Vertebrae</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Sisi</creatorcontrib><creatorcontrib>Lassalle, Louis</creatorcontrib><creatorcontrib>Mekki, Ahmed</creatorcontrib><creatorcontrib>Appert, Gautier</creatorcontrib><creatorcontrib>Rannou, François</creatorcontrib><creatorcontrib>Nguyen, Christelle</creatorcontrib><creatorcontrib>Lefèvre-Colau, Marie-Martine</creatorcontrib><creatorcontrib>Mutschler, Céline</creatorcontrib><creatorcontrib>Drapé, Jean-Luc</creatorcontrib><creatorcontrib>Feydy, 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Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Sisi</au><au>Lassalle, Louis</au><au>Mekki, Ahmed</au><au>Appert, Gautier</au><au>Rannou, François</au><au>Nguyen, Christelle</au><au>Lefèvre-Colau, Marie-Martine</au><au>Mutschler, Céline</au><au>Drapé, Jean-Luc</au><au>Feydy, Antoine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Can T2-weighted Dixon fat-only images replace T1-weighted images in degenerative disc disease with Modic changes on lumbar spine MRI?</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>31</volume><issue>12</issue><spage>9380</spage><epage>9389</epage><pages>9380-9389</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
To evaluate the diagnostic performance and interobserver agreement of a magnetic resonance imaging (MRI) protocol that only includes sagittal T2-weighted Dixon fat and water images as an alternative to a standard protocol that includes both sagittal T1-weighted sequence and T2-weighted Dixon water images as reference standard in lumbar degenerative disc disease with Modic changes.
Methods
From February 2017 to March 2019, 114 patients who underwent lumbar spine MRI for low back pain were included in this retrospective study. All MRI showed Modic changes at least at one vertebral level. Two radiologists read the standard protocol and 1 month later the alternative protocol. All MRI were assessed for Modic changes (types, location, extension) as well as structural changes (endplate defects, facet arthropathy, spinal stenosis, foraminal stenosis, Schmorl nodes, spondylolisthesis, disc bulges, and degeneration). Interobserver agreement was assessed, as well as diagnostic performance using the standard protocol as reference standard.
Results
Interobserver agreement was moderate to excellent (kappa ranging from 0.51 to 0.92). Diagnostic performance of the alternative protocol was good for detection of any Modic change (sensitivity = 100.00% [95% CI, 99.03–100.00]; specificity = 98.89% [95% CI, 98.02–99.44]), as well as for detection of each Modic subtype and structural variables (sensitivity respectively 100% and ranging from 88.43 to 99.75% ; specificity ranging respectively from 97.62 to 100% and 99.58 to 99.91% ).
Conclusions
Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images provide good diagnostic performance compared to T1-weighted images in lumbar degenerative disc disease with Modic changes, and could therefore allow for a shortened protocol.
Key Points
• Combined with T2-weighted Dixon water images, T2-weighted Dixon fat images (in comparison to T1-weighted sequence) can provide good diagnostic performance in lumbar degenerative disc disease with Modic changes.
• Interobserver agreement of the alternative protocol including sagittal T2-weighted Dixon fat and water images was substantial to excellent for every studied variable except for facet arthropathy.
• A shortened MRI protocol including T2-weighted Dixon sequence without T1-weighted sequence could be proposed in this clinical setting.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>33993328</pmid><doi>10.1007/s00330-021-07946-2</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-3498-9091</orcidid></addata></record> |
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subjects | Degeneration Degenerative disc disease Diagnostic Radiology Diagnostic systems Imaging Internal Medicine Interventional Radiology Intervertebral discs Low back pain Magnetic resonance imaging Medical imaging Medicine Medicine & Public Health Musculoskeletal Neuroradiology Performance evaluation Radiology Sensitivity Spinal stenosis Spine Spine (lumbar) Spondylolisthesis Ultrasound Vertebrae |
title | Can T2-weighted Dixon fat-only images replace T1-weighted images in degenerative disc disease with Modic changes on lumbar spine MRI? |
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