A national level estimation of population need for blood in India

Background The population need for blood is the total volume required to transfuse all the individuals who need transfusion in a defined population over a defined period. The clinical demand will arise when people with a disease or condition who require transfusion, access healthcare services, and s...

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Veröffentlicht in:Transfusion (Philadelphia, Pa.) Pa.), 2021-06, Vol.61 (6), p.1809-1821
Hauptverfasser: Mammen, Joy John, Asirvatham, Edwin Sam, Lakshmanan, Jeyaseelan, Sarman, Charishma Jones, Mani, Thenmozhi, Charles, Bimal, Upadhyaya, Sunita, Rajan, Shobini
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container_end_page 1821
container_issue 6
container_start_page 1809
container_title Transfusion (Philadelphia, Pa.)
container_volume 61
creator Mammen, Joy John
Asirvatham, Edwin Sam
Lakshmanan, Jeyaseelan
Sarman, Charishma Jones
Mani, Thenmozhi
Charles, Bimal
Upadhyaya, Sunita
Rajan, Shobini
description Background The population need for blood is the total volume required to transfuse all the individuals who need transfusion in a defined population over a defined period. The clinical demand will arise when people with a disease or condition who require transfusion, access healthcare services, and subsequently the clinicians request blood. Essentially, the conversion of need to demand must be maximum to avoid preventable mortality and morbidity. The study estimated the population need for blood in India. Methods The methodology included a comprehensive literature review to determine the diseases and conditions requiring transfusion, the population at risk, and prevalence or incidence; and Delphi method to estimate the percentage of people requiring transfusion, and the quantum. Results The estimated annual population need was 26.2 million units (95% CI; 17.9–38.0) of whole blood to address the need for red cells and other components after the separation process. The need for medical conditions was 11.0 million units (95% CI:8.7–14.7), followed by surgery 6.6 million (95% CI:3.8–10.0), pediatrics 5.0 million (95% CI:3.5–7.0), and obstetrics and gynecology 3.6 million units (95% CI:1.9–6.2). The gap between need and demand which depends upon the access and efficiency of healthcare service provision was estimated at 13 million units. Conclusion The study brings evidence to highlight the gap between need and demand and the importance of addressing it. It cannot be just the responsibility of blood transfusion or health systems, it requires a multi‐sectoral approach to address the barriers affecting the conversion of need to clinical demand for blood.
doi_str_mv 10.1111/trf.16369
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The clinical demand will arise when people with a disease or condition who require transfusion, access healthcare services, and subsequently the clinicians request blood. Essentially, the conversion of need to demand must be maximum to avoid preventable mortality and morbidity. The study estimated the population need for blood in India. Methods The methodology included a comprehensive literature review to determine the diseases and conditions requiring transfusion, the population at risk, and prevalence or incidence; and Delphi method to estimate the percentage of people requiring transfusion, and the quantum. Results The estimated annual population need was 26.2 million units (95% CI; 17.9–38.0) of whole blood to address the need for red cells and other components after the separation process. The need for medical conditions was 11.0 million units (95% CI:8.7–14.7), followed by surgery 6.6 million (95% CI:3.8–10.0), pediatrics 5.0 million (95% CI:3.5–7.0), and obstetrics and gynecology 3.6 million units (95% CI:1.9–6.2). The gap between need and demand which depends upon the access and efficiency of healthcare service provision was estimated at 13 million units. Conclusion The study brings evidence to highlight the gap between need and demand and the importance of addressing it. It cannot be just the responsibility of blood transfusion or health systems, it requires a multi‐sectoral approach to address the barriers affecting the conversion of need to clinical demand for blood.</description><identifier>ISSN: 0041-1132</identifier><identifier>EISSN: 1537-2995</identifier><identifier>DOI: 10.1111/trf.16369</identifier><identifier>PMID: 33991428</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley &amp; Sons, Inc</publisher><subject>Blood transfusion ; Conversion ; Delphi method ; Demand ; demand for blood ; Gynecology ; Health care ; Literature reviews ; Morbidity ; need and demand gap ; Obstetrics ; Pediatrics ; Population ; population need for blood ; Population statistics ; Population studies ; Preventable deaths ; Surgery ; Transfusion</subject><ispartof>Transfusion (Philadelphia, Pa.), 2021-06, Vol.61 (6), p.1809-1821</ispartof><rights>2021 AABB</rights><rights>2021 AABB.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3539-45e35805463933a1ce73b3fa30719cadef0f1946f57fda5547991be577c986f53</citedby><cites>FETCH-LOGICAL-c3539-45e35805463933a1ce73b3fa30719cadef0f1946f57fda5547991be577c986f53</cites><orcidid>0000-0002-7349-5660 ; 0000-0003-2090-6638</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Ftrf.16369$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Ftrf.16369$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33991428$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mammen, Joy John</creatorcontrib><creatorcontrib>Asirvatham, Edwin Sam</creatorcontrib><creatorcontrib>Lakshmanan, Jeyaseelan</creatorcontrib><creatorcontrib>Sarman, Charishma Jones</creatorcontrib><creatorcontrib>Mani, Thenmozhi</creatorcontrib><creatorcontrib>Charles, Bimal</creatorcontrib><creatorcontrib>Upadhyaya, Sunita</creatorcontrib><creatorcontrib>Rajan, Shobini</creatorcontrib><title>A national level estimation of population need for blood in India</title><title>Transfusion (Philadelphia, Pa.)</title><addtitle>Transfusion</addtitle><description>Background The population need for blood is the total volume required to transfuse all the individuals who need transfusion in a defined population over a defined period. The clinical demand will arise when people with a disease or condition who require transfusion, access healthcare services, and subsequently the clinicians request blood. Essentially, the conversion of need to demand must be maximum to avoid preventable mortality and morbidity. The study estimated the population need for blood in India. Methods The methodology included a comprehensive literature review to determine the diseases and conditions requiring transfusion, the population at risk, and prevalence or incidence; and Delphi method to estimate the percentage of people requiring transfusion, and the quantum. Results The estimated annual population need was 26.2 million units (95% CI; 17.9–38.0) of whole blood to address the need for red cells and other components after the separation process. The need for medical conditions was 11.0 million units (95% CI:8.7–14.7), followed by surgery 6.6 million (95% CI:3.8–10.0), pediatrics 5.0 million (95% CI:3.5–7.0), and obstetrics and gynecology 3.6 million units (95% CI:1.9–6.2). The gap between need and demand which depends upon the access and efficiency of healthcare service provision was estimated at 13 million units. Conclusion The study brings evidence to highlight the gap between need and demand and the importance of addressing it. It cannot be just the responsibility of blood transfusion or health systems, it requires a multi‐sectoral approach to address the barriers affecting the conversion of need to clinical demand for blood.</description><subject>Blood transfusion</subject><subject>Conversion</subject><subject>Delphi method</subject><subject>Demand</subject><subject>demand for blood</subject><subject>Gynecology</subject><subject>Health care</subject><subject>Literature reviews</subject><subject>Morbidity</subject><subject>need and demand gap</subject><subject>Obstetrics</subject><subject>Pediatrics</subject><subject>Population</subject><subject>population need for blood</subject><subject>Population statistics</subject><subject>Population studies</subject><subject>Preventable deaths</subject><subject>Surgery</subject><subject>Transfusion</subject><issn>0041-1132</issn><issn>1537-2995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kEFLAzEQhYMotlYP_gEJeNHDtsnOZrM5lmK1UBCknkN2N4Et6aYmXaX_3rRbPQjOZZjHx2PeQ-iWkjGNM9l5M6Y55OIMDSkDnqRCsHM0JCSjCaWQDtBVCGtCSCoIvUQDACFolhZDNJ3iVu0a1yqLrf7UFuuwazZHCTuDt27b2f5qta6xcR6X1rkaNy1etHWjrtGFUTbom9Meoff502r2kixfnxez6TKpgIFIMqaBFYRlOQgARSvNoQSjgHAqKlVrQwwVWW4YN7ViLOPxxVIzzitRRBVG6KH33Xr30cUv5aYJlbZWtdp1QaYsLSgHyHlE7_-ga9f5GPFAZWkKpAASqceeqrwLwWsjtz4m93tJiTz0KmOv8thrZO9Ojl250fUv-VNkBCY98NVYvf_fSa7e5r3lN1xnf04</recordid><startdate>202106</startdate><enddate>202106</enddate><creator>Mammen, Joy John</creator><creator>Asirvatham, Edwin Sam</creator><creator>Lakshmanan, Jeyaseelan</creator><creator>Sarman, Charishma Jones</creator><creator>Mani, Thenmozhi</creator><creator>Charles, Bimal</creator><creator>Upadhyaya, Sunita</creator><creator>Rajan, Shobini</creator><general>John Wiley &amp; 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Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Transfusion (Philadelphia, Pa.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mammen, Joy John</au><au>Asirvatham, Edwin Sam</au><au>Lakshmanan, Jeyaseelan</au><au>Sarman, Charishma Jones</au><au>Mani, Thenmozhi</au><au>Charles, Bimal</au><au>Upadhyaya, Sunita</au><au>Rajan, Shobini</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A national level estimation of population need for blood in India</atitle><jtitle>Transfusion (Philadelphia, Pa.)</jtitle><addtitle>Transfusion</addtitle><date>2021-06</date><risdate>2021</risdate><volume>61</volume><issue>6</issue><spage>1809</spage><epage>1821</epage><pages>1809-1821</pages><issn>0041-1132</issn><eissn>1537-2995</eissn><abstract>Background The population need for blood is the total volume required to transfuse all the individuals who need transfusion in a defined population over a defined period. 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The need for medical conditions was 11.0 million units (95% CI:8.7–14.7), followed by surgery 6.6 million (95% CI:3.8–10.0), pediatrics 5.0 million (95% CI:3.5–7.0), and obstetrics and gynecology 3.6 million units (95% CI:1.9–6.2). The gap between need and demand which depends upon the access and efficiency of healthcare service provision was estimated at 13 million units. Conclusion The study brings evidence to highlight the gap between need and demand and the importance of addressing it. It cannot be just the responsibility of blood transfusion or health systems, it requires a multi‐sectoral approach to address the barriers affecting the conversion of need to clinical demand for blood.</abstract><cop>Hoboken, USA</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>33991428</pmid><doi>10.1111/trf.16369</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-7349-5660</orcidid><orcidid>https://orcid.org/0000-0003-2090-6638</orcidid></addata></record>
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source Wiley Online Library Journals Frontfile Complete
subjects Blood transfusion
Conversion
Delphi method
Demand
demand for blood
Gynecology
Health care
Literature reviews
Morbidity
need and demand gap
Obstetrics
Pediatrics
Population
population need for blood
Population statistics
Population studies
Preventable deaths
Surgery
Transfusion
title A national level estimation of population need for blood in India
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