Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania

Pediatric aneurysms are rare, occurring in under 5% of cases, and their clinical presentation, rupture probability, location, and outcome differ from those in adults. The present study aimed to analyze the demographic characteristics and surgical outcomes of the largest series of patients with pedia...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Turkish neurosurgery 2021-01, Vol.31 (5), p.740-744
Hauptverfasser: Ciurea, Alexandru-Vlad, Mohan, Aurel, Voicu, Andrei, Saceleanu, Vicentiu, Moreanu, Mihai-Stelian, Ples, Horia
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 744
container_issue 5
container_start_page 740
container_title Turkish neurosurgery
container_volume 31
creator Ciurea, Alexandru-Vlad
Mohan, Aurel
Voicu, Andrei
Saceleanu, Vicentiu
Moreanu, Mihai-Stelian
Ples, Horia
description Pediatric aneurysms are rare, occurring in under 5% of cases, and their clinical presentation, rupture probability, location, and outcome differ from those in adults. The present study aimed to analyze the demographic characteristics and surgical outcomes of the largest series of patients with pediatric aneurysms reported in Romania, in consideration of the primary factors that lead to good long-term outcomes. Given that all cases involved ruptured aneurysms, we also investigated the ability of microsurgical clipping to prevent massive hemorrhage and aggravation of neurological deficits. This multicenter retrospective study included 47 pediatric patients ( 16 years old) who underwent operation over the 20-year period between January 1999 and January 2019. We analyzed medical records and imaging findings in each patient. Treatment consisted of open microsurgical dissection (clipping) and endovascular embolization (coiling). Mean patient age was 14.3 years, ranging from 5 months to 16 years, with 28 boys (59.5%) and 19 girls (40.4%). In our series, pediatric aneurysms represented 6.1% of all intracranial aneurysms (771 cases). Clinical features were dominated by headache (45 cases, 95.7%), neck stiffness (43 cases, 91.4%) and vomiting (42 cases, 89.3%). The most frequently involved locations were the anterior communicating artery (17 cases, 36.1%), middle cerebral artery (12 cases, 25.5%), and internal carotid artery bifurcation (9 cases, 19.1%). Glasgow Outcome Scale scores at 6 months indicated good recovery in 36 patients (76.5%), moderate disability in nine patients (19.1%), severe disability in one patient (2.1%), and (preoperative) death in one patient (2.1%). Intracranial aneurysms in children are very rare. Early diagnosis based on brain imaging and microsurgical treatment is essential for attaining excellent results. Primary factors such as preoperative status, child profile, aneurysm size, treatment choice, and timing of the operation influence both short and long-term outcomes.
doi_str_mv 10.5137/1019-5149.JTN.32954-20.2
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2526136147</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2526136147</sourcerecordid><originalsourceid>FETCH-LOGICAL-c310t-b9e6a859f643747eb1e1f85d3bdbd3a27d9816f4a7f45a8aef1fad91595bcf313</originalsourceid><addsrcrecordid>eNo9kElPwzAQhX0A0VL4C8hHLgkeL0l8RBWrKpBQOVuOFzDKUuzk0H9PQqGnkd68N_P0IYSB5AJYeQMEZCaAy_x5-5IzKgXPKMnpCVoeVwt0ntIXIUVBAc7QgjFZVpTyJdquP3XUZnAxpCGYhHVncRrjRzC6wf04mL51Cfce75wNeojB4NANUyTqLkwW3bkx7lObJhm_9e2sXqBTr5vkLv_mCr3f323Xj9nm9eFpfbvJDAMyZLV0ha6E9AVnJS9dDQ58JSyrbW2ZpqWVFRSe69JzoSvtPHhtJQgpauMZsBW6Ptzdxf57dGlQbUjGNc1Uqh-TooIWwArg5WStDlYT-5Si82oXQ6vjXgFRM0c1w1IzLDVxVL8cFSWKTtGrvy9j3Tp7DP5DZD8dSXLX</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2526136147</pqid></control><display><type>article</type><title>Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania</title><source>EZB-FREE-00999 freely available EZB journals</source><creator>Ciurea, Alexandru-Vlad ; Mohan, Aurel ; Voicu, Andrei ; Saceleanu, Vicentiu ; Moreanu, Mihai-Stelian ; Ples, Horia</creator><creatorcontrib>Ciurea, Alexandru-Vlad ; Mohan, Aurel ; Voicu, Andrei ; Saceleanu, Vicentiu ; Moreanu, Mihai-Stelian ; Ples, Horia</creatorcontrib><description>Pediatric aneurysms are rare, occurring in under 5% of cases, and their clinical presentation, rupture probability, location, and outcome differ from those in adults. The present study aimed to analyze the demographic characteristics and surgical outcomes of the largest series of patients with pediatric aneurysms reported in Romania, in consideration of the primary factors that lead to good long-term outcomes. Given that all cases involved ruptured aneurysms, we also investigated the ability of microsurgical clipping to prevent massive hemorrhage and aggravation of neurological deficits. This multicenter retrospective study included 47 pediatric patients ( 16 years old) who underwent operation over the 20-year period between January 1999 and January 2019. We analyzed medical records and imaging findings in each patient. Treatment consisted of open microsurgical dissection (clipping) and endovascular embolization (coiling). Mean patient age was 14.3 years, ranging from 5 months to 16 years, with 28 boys (59.5%) and 19 girls (40.4%). In our series, pediatric aneurysms represented 6.1% of all intracranial aneurysms (771 cases). Clinical features were dominated by headache (45 cases, 95.7%), neck stiffness (43 cases, 91.4%) and vomiting (42 cases, 89.3%). The most frequently involved locations were the anterior communicating artery (17 cases, 36.1%), middle cerebral artery (12 cases, 25.5%), and internal carotid artery bifurcation (9 cases, 19.1%). Glasgow Outcome Scale scores at 6 months indicated good recovery in 36 patients (76.5%), moderate disability in nine patients (19.1%), severe disability in one patient (2.1%), and (preoperative) death in one patient (2.1%). Intracranial aneurysms in children are very rare. Early diagnosis based on brain imaging and microsurgical treatment is essential for attaining excellent results. Primary factors such as preoperative status, child profile, aneurysm size, treatment choice, and timing of the operation influence both short and long-term outcomes.</description><identifier>ISSN: 1019-5149</identifier><identifier>DOI: 10.5137/1019-5149.JTN.32954-20.2</identifier><identifier>PMID: 33978224</identifier><language>eng</language><publisher>Turkey</publisher><ispartof>Turkish neurosurgery, 2021-01, Vol.31 (5), p.740-744</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33978224$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ciurea, Alexandru-Vlad</creatorcontrib><creatorcontrib>Mohan, Aurel</creatorcontrib><creatorcontrib>Voicu, Andrei</creatorcontrib><creatorcontrib>Saceleanu, Vicentiu</creatorcontrib><creatorcontrib>Moreanu, Mihai-Stelian</creatorcontrib><creatorcontrib>Ples, Horia</creatorcontrib><title>Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania</title><title>Turkish neurosurgery</title><addtitle>Turk Neurosurg</addtitle><description>Pediatric aneurysms are rare, occurring in under 5% of cases, and their clinical presentation, rupture probability, location, and outcome differ from those in adults. The present study aimed to analyze the demographic characteristics and surgical outcomes of the largest series of patients with pediatric aneurysms reported in Romania, in consideration of the primary factors that lead to good long-term outcomes. Given that all cases involved ruptured aneurysms, we also investigated the ability of microsurgical clipping to prevent massive hemorrhage and aggravation of neurological deficits. This multicenter retrospective study included 47 pediatric patients ( 16 years old) who underwent operation over the 20-year period between January 1999 and January 2019. We analyzed medical records and imaging findings in each patient. Treatment consisted of open microsurgical dissection (clipping) and endovascular embolization (coiling). Mean patient age was 14.3 years, ranging from 5 months to 16 years, with 28 boys (59.5%) and 19 girls (40.4%). In our series, pediatric aneurysms represented 6.1% of all intracranial aneurysms (771 cases). Clinical features were dominated by headache (45 cases, 95.7%), neck stiffness (43 cases, 91.4%) and vomiting (42 cases, 89.3%). The most frequently involved locations were the anterior communicating artery (17 cases, 36.1%), middle cerebral artery (12 cases, 25.5%), and internal carotid artery bifurcation (9 cases, 19.1%). Glasgow Outcome Scale scores at 6 months indicated good recovery in 36 patients (76.5%), moderate disability in nine patients (19.1%), severe disability in one patient (2.1%), and (preoperative) death in one patient (2.1%). Intracranial aneurysms in children are very rare. Early diagnosis based on brain imaging and microsurgical treatment is essential for attaining excellent results. Primary factors such as preoperative status, child profile, aneurysm size, treatment choice, and timing of the operation influence both short and long-term outcomes.</description><issn>1019-5149</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNo9kElPwzAQhX0A0VL4C8hHLgkeL0l8RBWrKpBQOVuOFzDKUuzk0H9PQqGnkd68N_P0IYSB5AJYeQMEZCaAy_x5-5IzKgXPKMnpCVoeVwt0ntIXIUVBAc7QgjFZVpTyJdquP3XUZnAxpCGYhHVncRrjRzC6wf04mL51Cfce75wNeojB4NANUyTqLkwW3bkx7lObJhm_9e2sXqBTr5vkLv_mCr3f323Xj9nm9eFpfbvJDAMyZLV0ha6E9AVnJS9dDQ58JSyrbW2ZpqWVFRSe69JzoSvtPHhtJQgpauMZsBW6Ptzdxf57dGlQbUjGNc1Uqh-TooIWwArg5WStDlYT-5Si82oXQ6vjXgFRM0c1w1IzLDVxVL8cFSWKTtGrvy9j3Tp7DP5DZD8dSXLX</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Ciurea, Alexandru-Vlad</creator><creator>Mohan, Aurel</creator><creator>Voicu, Andrei</creator><creator>Saceleanu, Vicentiu</creator><creator>Moreanu, Mihai-Stelian</creator><creator>Ples, Horia</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20210101</creationdate><title>Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania</title><author>Ciurea, Alexandru-Vlad ; Mohan, Aurel ; Voicu, Andrei ; Saceleanu, Vicentiu ; Moreanu, Mihai-Stelian ; Ples, Horia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c310t-b9e6a859f643747eb1e1f85d3bdbd3a27d9816f4a7f45a8aef1fad91595bcf313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ciurea, Alexandru-Vlad</creatorcontrib><creatorcontrib>Mohan, Aurel</creatorcontrib><creatorcontrib>Voicu, Andrei</creatorcontrib><creatorcontrib>Saceleanu, Vicentiu</creatorcontrib><creatorcontrib>Moreanu, Mihai-Stelian</creatorcontrib><creatorcontrib>Ples, Horia</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Turkish neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ciurea, Alexandru-Vlad</au><au>Mohan, Aurel</au><au>Voicu, Andrei</au><au>Saceleanu, Vicentiu</au><au>Moreanu, Mihai-Stelian</au><au>Ples, Horia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania</atitle><jtitle>Turkish neurosurgery</jtitle><addtitle>Turk Neurosurg</addtitle><date>2021-01-01</date><risdate>2021</risdate><volume>31</volume><issue>5</issue><spage>740</spage><epage>744</epage><pages>740-744</pages><issn>1019-5149</issn><abstract>Pediatric aneurysms are rare, occurring in under 5% of cases, and their clinical presentation, rupture probability, location, and outcome differ from those in adults. The present study aimed to analyze the demographic characteristics and surgical outcomes of the largest series of patients with pediatric aneurysms reported in Romania, in consideration of the primary factors that lead to good long-term outcomes. Given that all cases involved ruptured aneurysms, we also investigated the ability of microsurgical clipping to prevent massive hemorrhage and aggravation of neurological deficits. This multicenter retrospective study included 47 pediatric patients ( 16 years old) who underwent operation over the 20-year period between January 1999 and January 2019. We analyzed medical records and imaging findings in each patient. Treatment consisted of open microsurgical dissection (clipping) and endovascular embolization (coiling). Mean patient age was 14.3 years, ranging from 5 months to 16 years, with 28 boys (59.5%) and 19 girls (40.4%). In our series, pediatric aneurysms represented 6.1% of all intracranial aneurysms (771 cases). Clinical features were dominated by headache (45 cases, 95.7%), neck stiffness (43 cases, 91.4%) and vomiting (42 cases, 89.3%). The most frequently involved locations were the anterior communicating artery (17 cases, 36.1%), middle cerebral artery (12 cases, 25.5%), and internal carotid artery bifurcation (9 cases, 19.1%). Glasgow Outcome Scale scores at 6 months indicated good recovery in 36 patients (76.5%), moderate disability in nine patients (19.1%), severe disability in one patient (2.1%), and (preoperative) death in one patient (2.1%). Intracranial aneurysms in children are very rare. Early diagnosis based on brain imaging and microsurgical treatment is essential for attaining excellent results. Primary factors such as preoperative status, child profile, aneurysm size, treatment choice, and timing of the operation influence both short and long-term outcomes.</abstract><cop>Turkey</cop><pmid>33978224</pmid><doi>10.5137/1019-5149.JTN.32954-20.2</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1019-5149
ispartof Turkish neurosurgery, 2021-01, Vol.31 (5), p.740-744
issn 1019-5149
language eng
recordid cdi_proquest_miscellaneous_2526136147
source EZB-FREE-00999 freely available EZB journals
title Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T21%3A51%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Characteristics%20and%20surgical%20outcomes%20of%20pediatric%20intracranial%20aneurysms%20in%20Romania&rft.jtitle=Turkish%20neurosurgery&rft.au=Ciurea,%20Alexandru-Vlad&rft.date=2021-01-01&rft.volume=31&rft.issue=5&rft.spage=740&rft.epage=744&rft.pages=740-744&rft.issn=1019-5149&rft_id=info:doi/10.5137/1019-5149.JTN.32954-20.2&rft_dat=%3Cproquest_cross%3E2526136147%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2526136147&rft_id=info:pmid/33978224&rfr_iscdi=true