A Novel In Vitro and In Silico System for Analyzing Complex Mechanobiological Behavior of Chondrocytes in Three-Dimensional Hydrogel Constructs

Physiological loading is essential for the maintenance of articular cartilage through the regulation of tissue remodeling. To correctly understand the behavior of chondrocytes in their native environment, cell stimulating devices and bioreactors have been developed to examine the effect of mechanica...

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Veröffentlicht in:	Journal of biomechanical engineering 2021-08, Vol.143 (8)
Hauptverfasser:	Leung, Sophia, Kim, Jung-Joo, Musson, David S, McGlashan, Sue R, Cornish, Jillian, Anderson, Iain, Shim, Vickie B. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomechanical Phenomena Cell Survival Cells, Cultured Chondrocytes - cytology Computer Simulation Hydrogels - chemistry Models, Biological Stress, Mechanical
Online-Zugang:	Volltext
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