The association between treatment and systemic inflammation in acromegaly

Acromegaly is characterized by an excess of growth hormone (GH) and insulin like growth-factor 1 (IGF1), and it is strongly associated with cardiovascular diseases (CVD). Both acute and long-lasting pro-inflammatory effects have been attributed to IGF1. Previous results suggest the presence of syste...

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Veröffentlicht in:	Growth hormone & IGF research 2021-04, Vol.57-58, p.101391-101391, Article 101391
Hauptverfasser:	Wolters, T.L.C., van der Heijden, C.D.C.C., Pinzariu, O., Hijmans-Kersten, B.T.P., Jacobs, C., Kaffa, C., Hoischen, A., Netea, M.G., Smit, J.W.A., Thijssen, D.H.J., Georgescu, C.E., Riksen, N.P., Netea-Maier, R.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acromegaly Acromegaly - metabolism Acromegaly - physiopathology Acromegaly - therapy Adenoma - metabolism Adenoma - physiopathology Adenoma - therapy Adult Aged Antineoplastic Agents, Hormonal - therapeutic use Cardiovascular disease Carotid Intima-Media Thickness Cytokines - metabolism Dopamine Agonists - therapeutic use E-Selectin - metabolism Endothelial dysfunction Endothelium, Vascular - physiopathology Female Growth Hormone-Secreting Pituitary Adenoma - metabolism Growth Hormone-Secreting Pituitary Adenoma - physiopathology Growth Hormone-Secreting Pituitary Adenoma - therapy Human Growth Hormone - analogs & derivatives Human Growth Hormone - therapeutic use Humans IGF1 Inflammation Inflammation - metabolism Inflammation - physiopathology Interleukin-18 - metabolism Male Matrix Metalloproteinase 2 - metabolism Middle Aged Neurosurgical Procedures Pulse Wave Analysis Radiotherapy Somatostatin - analogs & derivatives Treatment Outcome Vascular Cell Adhesion Molecule-1 - metabolism
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