Sensory Innervation of Human Bone: An Immunohistochemical Study to Further Understand Bone Pain

•Innervation density across various human bones was studied by immunohistochemistry.•The periosteum was most densely innervated, followed by bone marrow and cortex.•Thoracic spine and parietal bones showed most and least innervation, respectively.•Innervation density decreased with age, in the elder...

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Veröffentlicht in:	The journal of pain 2021-11, Vol.22 (11), p.1385-1395
Hauptverfasser:	Steverink, Jasper G., Oostinga, Douwe, van Tol, Floris R., van Rijen, Mattie H.P., Mackaaij, Claire, Verlinde-Schellekens, Suzanne A.M.W., Oosterman, Bas J., Van Wijck, Albert J.M., Roeling, Tom A.P., Verlaan, Jorrit-Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Bone Diseases bone marrow Bone Marrow - innervation Bone pain cortex Cortical Bone - innervation Humans Immunohistochemistry innervation density Musculoskeletal Pain periosteum Periosteum - innervation
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