AminoBODIPY Conjugates for Targeted Drug Delivery Systems and Real-Time Monitoring of Drug Release

In this work, we report two concepts of drug delivery based on small-molecule drug conjugates with the ability of specific targeting and drug release monitoring via ratiometric fluorescence. The functionality of these concepts has been verified by two model systems consisting of three parts: (i) flu...

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Veröffentlicht in:	Molecular pharmaceutics 2021-06, Vol.18 (6), p.2385-2396
Hauptverfasser:	Porubský, Martin, Gurská, Soňa, Stanková, Jarmila, Hajdúch, Marián, Džubák, Petr, Hlaváč, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Boron Compounds - chemistry Drug Carriers - chemistry Drug Carriers - pharmacology Drug Liberation Fluorescence Fluorescent Dyes - chemistry Glutathione - metabolism HeLa Cells Humans Hydroxyquinolines - administration & dosage Hydroxyquinolines - pharmacokinetics Integrin alphaVbeta3 - metabolism Oligopeptides - chemistry Oligopeptides - pharmacology
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