Effect of the local probiotics in the therapy of periodontitis A randomized prospective study
Objectives The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in t...
Gespeichert in:
| Veröffentlicht in: | International journal of dental hygiene 2022-05, Vol.20 (2), p.401-407 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 407 |
|---|---|
| container_issue | 2 |
| container_start_page | 401 |
| container_title | International journal of dental hygiene |
| container_volume | 20 |
| creator | Minić, Ivan Pejčić, Ana Bradić‐Vasić, Marija |
| description | Objectives
The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in the treatment of periodontitis as an adjunctive therapy to scaling and root planning (SRP).
Methods
The study involved 80 patients diagnosed with periodontitis. All participants underwent SRP therapy. Semi‐solid probiotic was then locally applied to the periodontal pocket in randomly selected patients for the test group (40 of them). The other 40 patients were in the control group. Clinical parameters including periodontal pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI) were measured at baseline, and at 7 and 30 days after treatment.
Results
Seven days after the applied therapy in the test and control group, there was a significant decrease in the values or BOP (p |
| doi_str_mv | 10.1111/idh.12509 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2524353182</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2524353182</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3539-b5f07c3d3f4e7af96056c8451a02833c8b3bb48b4d7d597afc8b8d66b5bc16963</originalsourceid><addsrcrecordid>eNp1kE9LwzAYh4Mobk4PfgEJeNFDt6Rp0vY45nTCwIseJTR_yjLapjatUj-92Tp3EEwICS9PfnnzAHCN0RT7MTNqM8UhRekJGGOGcEARiU-P5zAdgQvntgiFftJzMCIkZRFG0Ri8L_NcyxbaHLYbDQsrswLWjRXGtkY6aKp93a8mq_sdVuvGWGWr1rTGwTlsskrZ0nxrtbvnap9mPjV0baf6S3CWZ4XTV4d9At4el6-LVbB-eXpezNeBJJSkgaA5iiVRJI90nOUpQ5TJJKI4Q2FCiEwEESJKRKRiRVNP-EqiGBNUSMxSRibgbsj1HXx02rW8NE7qosgqbTvHQxpG_iWchB69_YNubddUvjseMhohnHhhnrofKOm_5Bqd87oxZdb0HCO-c869c7537tmbQ2InSq2O5K9kD8wG4MsUuv8_iT8_rIbIH_GGiqM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2654018502</pqid></control><display><type>article</type><title>Effect of the local probiotics in the therapy of periodontitis A randomized prospective study</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Minić, Ivan ; Pejčić, Ana ; Bradić‐Vasić, Marija</creator><creatorcontrib>Minić, Ivan ; Pejčić, Ana ; Bradić‐Vasić, Marija</creatorcontrib><description>Objectives
The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in the treatment of periodontitis as an adjunctive therapy to scaling and root planning (SRP).
Methods
The study involved 80 patients diagnosed with periodontitis. All participants underwent SRP therapy. Semi‐solid probiotic was then locally applied to the periodontal pocket in randomly selected patients for the test group (40 of them). The other 40 patients were in the control group. Clinical parameters including periodontal pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI) were measured at baseline, and at 7 and 30 days after treatment.
Results
Seven days after the applied therapy in the test and control group, there was a significant decrease in the values or BOP (p < .001), while the values of other parameters did not show a statistically significant difference (p < .05). One month after the therapy in both groups, there was a statistically significant difference in the values of all clinical parameters (p < .001).
Conclusions
Based on the results of this pilot study, it can be said that, during periodontal treatment, topical application of probiotics in combination with SRP increases the effectiveness of conventional non‐surgical therapy of periodontitis.</description><identifier>ISSN: 1601-5029</identifier><identifier>EISSN: 1601-5037</identifier><identifier>DOI: 10.1111/idh.12509</identifier><identifier>PMID: 33964104</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Chronic Periodontitis - therapy ; Dental Scaling - methods ; Gum disease ; Humans ; Immune response ; Patients ; periodontal indices ; Periodontal Pocket ; Periodontitis ; Pilot Projects ; Plaque index ; Probiotics ; Probiotics - therapeutic use ; Prospective Studies ; Root Planing - methods ; Statistical analysis ; therapy ; Topical application</subject><ispartof>International journal of dental hygiene, 2022-05, Vol.20 (2), p.401-407</ispartof><rights>2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3539-b5f07c3d3f4e7af96056c8451a02833c8b3bb48b4d7d597afc8b8d66b5bc16963</citedby><cites>FETCH-LOGICAL-c3539-b5f07c3d3f4e7af96056c8451a02833c8b3bb48b4d7d597afc8b8d66b5bc16963</cites><orcidid>0000-0001-9374-388X ; 0000-0003-0168-2392</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fidh.12509$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fidh.12509$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33964104$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Minić, Ivan</creatorcontrib><creatorcontrib>Pejčić, Ana</creatorcontrib><creatorcontrib>Bradić‐Vasić, Marija</creatorcontrib><title>Effect of the local probiotics in the therapy of periodontitis A randomized prospective study</title><title>International journal of dental hygiene</title><addtitle>Int J Dent Hyg</addtitle><description>Objectives
The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in the treatment of periodontitis as an adjunctive therapy to scaling and root planning (SRP).
Methods
The study involved 80 patients diagnosed with periodontitis. All participants underwent SRP therapy. Semi‐solid probiotic was then locally applied to the periodontal pocket in randomly selected patients for the test group (40 of them). The other 40 patients were in the control group. Clinical parameters including periodontal pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI) were measured at baseline, and at 7 and 30 days after treatment.
Results
Seven days after the applied therapy in the test and control group, there was a significant decrease in the values or BOP (p < .001), while the values of other parameters did not show a statistically significant difference (p < .05). One month after the therapy in both groups, there was a statistically significant difference in the values of all clinical parameters (p < .001).
Conclusions
Based on the results of this pilot study, it can be said that, during periodontal treatment, topical application of probiotics in combination with SRP increases the effectiveness of conventional non‐surgical therapy of periodontitis.</description><subject>Chronic Periodontitis - therapy</subject><subject>Dental Scaling - methods</subject><subject>Gum disease</subject><subject>Humans</subject><subject>Immune response</subject><subject>Patients</subject><subject>periodontal indices</subject><subject>Periodontal Pocket</subject><subject>Periodontitis</subject><subject>Pilot Projects</subject><subject>Plaque index</subject><subject>Probiotics</subject><subject>Probiotics - therapeutic use</subject><subject>Prospective Studies</subject><subject>Root Planing - methods</subject><subject>Statistical analysis</subject><subject>therapy</subject><subject>Topical application</subject><issn>1601-5029</issn><issn>1601-5037</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE9LwzAYh4Mobk4PfgEJeNFDt6Rp0vY45nTCwIseJTR_yjLapjatUj-92Tp3EEwICS9PfnnzAHCN0RT7MTNqM8UhRekJGGOGcEARiU-P5zAdgQvntgiFftJzMCIkZRFG0Ri8L_NcyxbaHLYbDQsrswLWjRXGtkY6aKp93a8mq_sdVuvGWGWr1rTGwTlsskrZ0nxrtbvnap9mPjV0baf6S3CWZ4XTV4d9At4el6-LVbB-eXpezNeBJJSkgaA5iiVRJI90nOUpQ5TJJKI4Q2FCiEwEESJKRKRiRVNP-EqiGBNUSMxSRibgbsj1HXx02rW8NE7qosgqbTvHQxpG_iWchB69_YNubddUvjseMhohnHhhnrofKOm_5Bqd87oxZdb0HCO-c869c7537tmbQ2InSq2O5K9kD8wG4MsUuv8_iT8_rIbIH_GGiqM</recordid><startdate>202205</startdate><enddate>202205</enddate><creator>Minić, Ivan</creator><creator>Pejčić, Ana</creator><creator>Bradić‐Vasić, Marija</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9374-388X</orcidid><orcidid>https://orcid.org/0000-0003-0168-2392</orcidid></search><sort><creationdate>202205</creationdate><title>Effect of the local probiotics in the therapy of periodontitis A randomized prospective study</title><author>Minić, Ivan ; Pejčić, Ana ; Bradić‐Vasić, Marija</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3539-b5f07c3d3f4e7af96056c8451a02833c8b3bb48b4d7d597afc8b8d66b5bc16963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Chronic Periodontitis - therapy</topic><topic>Dental Scaling - methods</topic><topic>Gum disease</topic><topic>Humans</topic><topic>Immune response</topic><topic>Patients</topic><topic>periodontal indices</topic><topic>Periodontal Pocket</topic><topic>Periodontitis</topic><topic>Pilot Projects</topic><topic>Plaque index</topic><topic>Probiotics</topic><topic>Probiotics - therapeutic use</topic><topic>Prospective Studies</topic><topic>Root Planing - methods</topic><topic>Statistical analysis</topic><topic>therapy</topic><topic>Topical application</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Minić, Ivan</creatorcontrib><creatorcontrib>Pejčić, Ana</creatorcontrib><creatorcontrib>Bradić‐Vasić, Marija</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of dental hygiene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Minić, Ivan</au><au>Pejčić, Ana</au><au>Bradić‐Vasić, Marija</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of the local probiotics in the therapy of periodontitis A randomized prospective study</atitle><jtitle>International journal of dental hygiene</jtitle><addtitle>Int J Dent Hyg</addtitle><date>2022-05</date><risdate>2022</risdate><volume>20</volume><issue>2</issue><spage>401</spage><epage>407</epage><pages>401-407</pages><issn>1601-5029</issn><eissn>1601-5037</eissn><abstract>Objectives
The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in the treatment of periodontitis as an adjunctive therapy to scaling and root planning (SRP).
Methods
The study involved 80 patients diagnosed with periodontitis. All participants underwent SRP therapy. Semi‐solid probiotic was then locally applied to the periodontal pocket in randomly selected patients for the test group (40 of them). The other 40 patients were in the control group. Clinical parameters including periodontal pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI) were measured at baseline, and at 7 and 30 days after treatment.
Results
Seven days after the applied therapy in the test and control group, there was a significant decrease in the values or BOP (p < .001), while the values of other parameters did not show a statistically significant difference (p < .05). One month after the therapy in both groups, there was a statistically significant difference in the values of all clinical parameters (p < .001).
Conclusions
Based on the results of this pilot study, it can be said that, during periodontal treatment, topical application of probiotics in combination with SRP increases the effectiveness of conventional non‐surgical therapy of periodontitis.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>33964104</pmid><doi>10.1111/idh.12509</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-9374-388X</orcidid><orcidid>https://orcid.org/0000-0003-0168-2392</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1601-5029 |
| ispartof | International journal of dental hygiene, 2022-05, Vol.20 (2), p.401-407 |
| issn | 1601-5029 1601-5037 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2524353182 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Chronic Periodontitis - therapy Dental Scaling - methods Gum disease Humans Immune response Patients periodontal indices Periodontal Pocket Periodontitis Pilot Projects Plaque index Probiotics Probiotics - therapeutic use Prospective Studies Root Planing - methods Statistical analysis therapy Topical application |
| title | Effect of the local probiotics in the therapy of periodontitis A randomized prospective study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T12%3A16%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20the%20local%20probiotics%20in%20the%20therapy%20of%20periodontitis%20A%20randomized%20prospective%20study&rft.jtitle=International%20journal%20of%20dental%20hygiene&rft.au=Mini%C4%87,%20Ivan&rft.date=2022-05&rft.volume=20&rft.issue=2&rft.spage=401&rft.epage=407&rft.pages=401-407&rft.issn=1601-5029&rft.eissn=1601-5037&rft_id=info:doi/10.1111/idh.12509&rft_dat=%3Cproquest_cross%3E2524353182%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2654018502&rft_id=info:pmid/33964104&rfr_iscdi=true |