Prediction of treatment response from the microenvironment of tumor immunity in cervical cancer patients treated with chemoradiotherapy

To supplement clinical decision-making in the management of cervical cancer, various prognostic factors, including tumor immune microenvironments, were examined in patients with cervical cancer treated with definitive chemoradiotherapy. We retrospectively analyzed the expression of CD8, FoxP3, HLA-1...

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Veröffentlicht in:	Medical molecular morphology 2021-09, Vol.54 (3), p.245-252
Hauptverfasser:	Someya, Masanori, Tsuchiya, Takaaki, Fukushima, Yuki, Hasegawa, Tomokazu, Hori, Masakazu, Kitagawa, Mio, Gocho, Toshio, Mafune, Shoh, Ikeuchi, Yutaro, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Iwasaki, Masahiro, Matsuura, Motoki, Saito, Tsuyoshi, Matsumoto, Yoshihisa, Sakata, Koh-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anatomy B7-H1 Antigen - genetics Cancer therapies CD8 antigen CD8 Antigens - genetics Cervical cancer Cervix Chemoradiotherapy Chemotherapy Decision making DNA-Binding Proteins - genetics Female Forkhead Transcription Factors - genetics Foxp3 protein Gene Expression Regulation, Neoplastic Histocompatibility antigen HLA Humans Immunity Inflammation Japan Lymphocytes T Medical prognosis Medicine Medicine & Public Health Microenvironments Middle Aged Molecular Medicine Multivariate analysis Original Paper Pathology Patients PD-L1 protein Prognosis Radiation therapy Retrospective Studies Tumor Microenvironment - immunology Tumors Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - immunology Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - therapy
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