ZFP90 drives the initiation of colitis-associated colorectal cancer via a microbiota-dependent strategy

Chronic inflammation and gut microbiota dysbiosis are risk factors for colorectal cancer. In clinical practice, patients with inflammatory bowel disease (IBD) have a greatly increased risk of developing colitis-associated colorectal cancer (CAC). However, the underlying mechanism of the initiation o...

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Veröffentlicht in:	Gut microbes 2021-01, Vol.13 (1), p.1-20
Hauptverfasser:	Han, Ji-Xuan, Tao, Zhi-Hang, Qian, Yun, Yu, Chen-Yang, Li, Jialu, Kang, Zi-Ran, Lu, Shiyuan, Xie, Yuanhong, Hong, Jie, Chen, Haoyan, Chen, Ying-Xuan, Fang, Jing-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - classification Bacteria - genetics Bacteria - isolation & purification colitis-associated colorectal cancer Colitis-Associated Neoplasms - genetics Colitis-Associated Neoplasms - metabolism Colitis-Associated Neoplasms - microbiology Disease Progression Gastrointestinal Microbiome gut barrier gut microbiota Humans Male Mice Mice, Inbred C57BL Mice, Knockout prevotella copri Repressor Proteins - genetics Repressor Proteins - metabolism Research Paper ZFP90
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