UV–VIS spectra as potential process analytical technology (PAT) for measuring the density of compressed materials: Evaluation of the CIELAB color space

[Display omitted] •Influence of compression on visible (VIS) spectra of pharmaceutical materials.•Density determination via visible (VIS) spectroscopy using CIE color space.•Visible (VIS) spectra as potential process analytical technology (PAT) Measurement methods for determining the density of comp...

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Veröffentlicht in:	International journal of pharmaceutics 2021-06, Vol.603, p.120668-120668, Article 120668
Hauptverfasser:	Lillotte, Tim D., Joester, Maike, Frindt, Benjamin, Berghaus, Andreas, Lammens, Robert F., Wagner, Karl G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Color space Compression Partial least square regression (PLS) Principal component analysis (PCA) Process analytical technology (PAT) Spectrophotometry Tablet density
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