Eprosartan: A closer insight into its neuroprotective activity in rats with focal cerebral ischemia–reperfusion injury

Eprosartan (EPRO), an angiotensin receptor type‐1 (AT‐1) blocker, exhibited neuroprotective activities in ischemic stroke resulting from focal cerebral ischemia in rats. The current study aimed to clarify the neuroprotective role of EPRO in middle carotid artery occlusion (MCAO)‐induced ischemic str...

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Veröffentlicht in:	Journal of biochemical and molecular toxicology 2021-07, Vol.35 (7), p.e22796-n/a
Hauptverfasser:	Saad, Muhammad A. E., Fahmy, Mohamed I. M., Sayed, Rabab H., El‐Yamany, Muhammad F., El‐Naggar, Reham, Hegazy, Ahmed A. E., Al‐Shorbagy, Muhammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Apoptosis Attenuation Biomarkers Brain Carotid artery Caspase Caveolin Cerebral blood flow Edema eprosartan Gene expression Hippocampus Hypoxia Impairment Inflammation Ischemia Janus kinase Janus kinase 2 Kinases Neuroprotection neuroprotective Occlusion Oxidative stress rat Receiving Receptors Reperfusion Rodents Stroke Transcription factors Transducers
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