Muscarinic M4 and M5 receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol‐preferring rats

Background and Purpose Muscarinic acetylcholine receptors mediate alcohol consumption and seeking in rats. While M4 and M5 receptors have recently been implicated to mediate these behaviours in the striatum, their role in other brain regions remain unknown. The ventral tegmental area (VTA) and ventr...

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Veröffentlicht in:	British journal of pharmacology 2021-09, Vol.178 (18), p.3730-3746
Hauptverfasser:	Walker, Leigh C., Huckstep, Kate L., Chen, Nicola A., Hand, Lexi J., Lindsley, Craig W., Langmead, Christopher J., Lawrence, Andrew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors (muscarinic) Alcohol allosteric modulation Allosteric properties context Food consumption Hippocampus Locomotor activity Motivation muscarinic receptor Neostriatum Nucleus accumbens relapse Subiculum ventral subiculum ventral tegmental area Ventral tegmentum
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