Prophylactic and therapeutic vaccine against Pseudomonas aeruginosa keratitis using bacterial membrane vesicles

Pseudomonas aeruginosa (P. aeruginosa) infection is one of the major causes of keratitis. However, effective prophylactic and therapeutic vaccines against P. aeruginosa keratitis have yet to be developed. In this study, we explored the use of P. aeruginosa membrane vesicles (MVs) as a prophylactic v...

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Veröffentlicht in:	Vaccine 2021-05, Vol.39 (23), p.3152-3160
Hauptverfasser:	Ito, Saori, Nakamura, Jutaro, Fukuta, Michiko, Ura, Takehiro, Teshigawara, Takeshi, Fukushima, Jun, Mizuki, Nobuhisa, Okuda, Kenji, Shimada, Masaru
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antisera Bacteria Bacterial vesicles Cornea E coli Enzymes Gram-negative bacteria Gram-positive bacteria Immune system Immunization Immunization (passive) Immunoglobulin A Immunoglobulin G Infections Keratitis Laboratory animals Membrane vesicles membrane vesicles (MVs) Membranes Mouse model Pathogens Pseudomonas aeruginosa Pseudomonas aeruginosa keratitis Topical application Vaccine Vaccines Vesicles
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