Comparing two different low‐intensity shockwave therapy frequency protocols for nonbacterial chronic prostatitis/chronic pelvic pain syndrome: A two‐arm, parallel‐group randomized controlled trial
Background Despite encouraging results, the optimal low‐intensity shockwave therapy (LiST) protocol in patients with chronic prostatitis/chronic pelvic pain syndrome (CPPS) remains unknown. We conducted a two‐arm, parallel‐group, randomized controlled trial aiming to compare the efficacy and safety...
Gespeichert in:
| Veröffentlicht in: | The Prostate 2021-06, Vol.81 (9), p.499-507 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 507 |
|---|---|
| container_issue | 9 |
| container_start_page | 499 |
| container_title | The Prostate |
| container_volume | 81 |
| creator | Mykoniatis, Ioannis Pyrgidis, Nikolaos Kalyvianakis, Dimitrios Zilotis, Filimon Kapoteli, Paraskevi Fournaraki, Agrippina Hatzichristou, Dimitrios |
| description | Background
Despite encouraging results, the optimal low‐intensity shockwave therapy (LiST) protocol in patients with chronic prostatitis/chronic pelvic pain syndrome (CPPS) remains unknown. We conducted a two‐arm, parallel‐group, randomized controlled trial aiming to compare the efficacy and safety of six LiST sessions applied once or twice weekly.
Methods
Fifty patients with CP/CPPS type IIIb were randomly assigned to six LiST sessions once (Group A, n = 25) or twice weekly (Group B, n = 25). Both groups followed the same treatment protocol in terms of LiST application, impulses (5000/session), energy flux density (0.096 mJ/mm2) and frequency (5 Hz). Subsequently, all participants were evaluated at 1 and 3 months after completion of LiST protocol.
Results
At the follow‐up evaluations, LiST significantly improved the National Institutes of Health‐Chronic Prostatitis Symptom Index (NIH‐CPSI) total, pain and quality of life scores, as well as the International Index of Erectile Function–Erectile Domain (IIEF‐ED) in both groups (p |
| doi_str_mv | 10.1002/pros.24119 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2520892662</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2520892662</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3579-4f70ee81dfdeaf198430503ef9ac453e09c58ce4cf5418fc6e23c1c835f871193</originalsourceid><addsrcrecordid>eNp9kUtuFDEQhi0EIkNgwwGQJTYI0Ykf7ek2u2jES4oUxGPdctzljIPbbmx3Rp1VjsC5OAYnwc2ELFiwKtn16a-__kLoKSVHlBB2PMaQjlhNqbyHVpTIpiKkFvfRirCGVDXlzQF6lNIlIQUn7CE64FwySQRboZ-bMIwqWn-B8y7g3hoDEXzGLux-3fywPoNPNs84bYP-tlNXgPMWohpnbCJ8n8DrGRcDOejgEjYhYh_8udIZolUO620M3uoFSVllm206vvsDd7UUZT1Os-9jGOA1PlmMlNEqDq9KLyrnwJX3RQzTiKPyfRjsNfRYB59jKN0e52XWY_TAKJfgyW09RF_fvvmyeV-dnr37sDk5rTQXjaxq0xCAlvamB2WobGtOBOFgpNK14ECkFq2GWhtR09boNTCuqW65MG1TMuaH6MVet-xUAki5G2zS4JzyEKbUMcFIK9l6zQr6_B_0MkzRF3cLxSVlrawL9XJP6RJSimC6MdpBxbmjpFsu3C3pdX8uXOBnt5LT-QD9Hfr3pAWge2BnHcz_keo-fjr7vBf9DdFYuro</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2523912894</pqid></control><display><type>article</type><title>Comparing two different low‐intensity shockwave therapy frequency protocols for nonbacterial chronic prostatitis/chronic pelvic pain syndrome: A two‐arm, parallel‐group randomized controlled trial</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Mykoniatis, Ioannis ; Pyrgidis, Nikolaos ; Kalyvianakis, Dimitrios ; Zilotis, Filimon ; Kapoteli, Paraskevi ; Fournaraki, Agrippina ; Hatzichristou, Dimitrios</creator><creatorcontrib>Mykoniatis, Ioannis ; Pyrgidis, Nikolaos ; Kalyvianakis, Dimitrios ; Zilotis, Filimon ; Kapoteli, Paraskevi ; Fournaraki, Agrippina ; Hatzichristou, Dimitrios</creatorcontrib><description>Background
Despite encouraging results, the optimal low‐intensity shockwave therapy (LiST) protocol in patients with chronic prostatitis/chronic pelvic pain syndrome (CPPS) remains unknown. We conducted a two‐arm, parallel‐group, randomized controlled trial aiming to compare the efficacy and safety of six LiST sessions applied once or twice weekly.
Methods
Fifty patients with CP/CPPS type IIIb were randomly assigned to six LiST sessions once (Group A, n = 25) or twice weekly (Group B, n = 25). Both groups followed the same treatment protocol in terms of LiST application, impulses (5000/session), energy flux density (0.096 mJ/mm2) and frequency (5 Hz). Subsequently, all participants were evaluated at 1 and 3 months after completion of LiST protocol.
Results
At the follow‐up evaluations, LiST significantly improved the National Institutes of Health‐Chronic Prostatitis Symptom Index (NIH‐CPSI) total, pain and quality of life scores, as well as the International Index of Erectile Function–Erectile Domain (IIEF‐ED) in both groups (p < .001 for all measures). Comparing between the two groups, no significant differences were demonstrated in the NIH‐CPSI total, pain, urinary and quality of life scores, as well as in the International Prostate Symptom Score, IIEF–ED, and LiST‐induced pain at both follow‐up evaluations. Accordingly, no adverse events and no dropouts were observed in both groups.
Conclusion
Six sessions of LiST applied once weekly for 6 weeks or twice weekly for 3 weeks seem to be equally safe and effective in patients with CP/CPPS. Nevertheless, further studies are necessary, since LiST gradually gains its place for the management of CP/CPPS.</description><identifier>ISSN: 0270-4137</identifier><identifier>EISSN: 1097-0045</identifier><identifier>DOI: 10.1002/pros.24119</identifier><identifier>PMID: 33929052</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adult ; Adverse events ; Chronic pain ; chronic pelvic pain syndrome ; chronic prostatitis ; Clinical trials ; Extracorporeal Shockwave Therapy - methods ; Humans ; low‐intensity shockwave therapy ; Male ; Middle Aged ; Pain ; Pelvic Pain - therapy ; Prospective Studies ; Prostate ; Prostatitis ; Prostatitis - therapy ; Quality of Life ; randomized controlled trial ; Treatment Outcome</subject><ispartof>The Prostate, 2021-06, Vol.81 (9), p.499-507</ispartof><rights>2021 Wiley Periodicals LLC</rights><rights>2021 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3579-4f70ee81dfdeaf198430503ef9ac453e09c58ce4cf5418fc6e23c1c835f871193</citedby><cites>FETCH-LOGICAL-c3579-4f70ee81dfdeaf198430503ef9ac453e09c58ce4cf5418fc6e23c1c835f871193</cites><orcidid>0000-0002-3869-2888</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpros.24119$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpros.24119$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33929052$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mykoniatis, Ioannis</creatorcontrib><creatorcontrib>Pyrgidis, Nikolaos</creatorcontrib><creatorcontrib>Kalyvianakis, Dimitrios</creatorcontrib><creatorcontrib>Zilotis, Filimon</creatorcontrib><creatorcontrib>Kapoteli, Paraskevi</creatorcontrib><creatorcontrib>Fournaraki, Agrippina</creatorcontrib><creatorcontrib>Hatzichristou, Dimitrios</creatorcontrib><title>Comparing two different low‐intensity shockwave therapy frequency protocols for nonbacterial chronic prostatitis/chronic pelvic pain syndrome: A two‐arm, parallel‐group randomized controlled trial</title><title>The Prostate</title><addtitle>Prostate</addtitle><description>Background
Despite encouraging results, the optimal low‐intensity shockwave therapy (LiST) protocol in patients with chronic prostatitis/chronic pelvic pain syndrome (CPPS) remains unknown. We conducted a two‐arm, parallel‐group, randomized controlled trial aiming to compare the efficacy and safety of six LiST sessions applied once or twice weekly.
Methods
Fifty patients with CP/CPPS type IIIb were randomly assigned to six LiST sessions once (Group A, n = 25) or twice weekly (Group B, n = 25). Both groups followed the same treatment protocol in terms of LiST application, impulses (5000/session), energy flux density (0.096 mJ/mm2) and frequency (5 Hz). Subsequently, all participants were evaluated at 1 and 3 months after completion of LiST protocol.
Results
At the follow‐up evaluations, LiST significantly improved the National Institutes of Health‐Chronic Prostatitis Symptom Index (NIH‐CPSI) total, pain and quality of life scores, as well as the International Index of Erectile Function–Erectile Domain (IIEF‐ED) in both groups (p < .001 for all measures). Comparing between the two groups, no significant differences were demonstrated in the NIH‐CPSI total, pain, urinary and quality of life scores, as well as in the International Prostate Symptom Score, IIEF–ED, and LiST‐induced pain at both follow‐up evaluations. Accordingly, no adverse events and no dropouts were observed in both groups.
Conclusion
Six sessions of LiST applied once weekly for 6 weeks or twice weekly for 3 weeks seem to be equally safe and effective in patients with CP/CPPS. Nevertheless, further studies are necessary, since LiST gradually gains its place for the management of CP/CPPS.</description><subject>Adult</subject><subject>Adverse events</subject><subject>Chronic pain</subject><subject>chronic pelvic pain syndrome</subject><subject>chronic prostatitis</subject><subject>Clinical trials</subject><subject>Extracorporeal Shockwave Therapy - methods</subject><subject>Humans</subject><subject>low‐intensity shockwave therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pain</subject><subject>Pelvic Pain - therapy</subject><subject>Prospective Studies</subject><subject>Prostate</subject><subject>Prostatitis</subject><subject>Prostatitis - therapy</subject><subject>Quality of Life</subject><subject>randomized controlled trial</subject><subject>Treatment Outcome</subject><issn>0270-4137</issn><issn>1097-0045</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtuFDEQhi0EIkNgwwGQJTYI0Ykf7ek2u2jES4oUxGPdctzljIPbbmx3Rp1VjsC5OAYnwc2ELFiwKtn16a-__kLoKSVHlBB2PMaQjlhNqbyHVpTIpiKkFvfRirCGVDXlzQF6lNIlIQUn7CE64FwySQRboZ-bMIwqWn-B8y7g3hoDEXzGLux-3fywPoNPNs84bYP-tlNXgPMWohpnbCJ8n8DrGRcDOejgEjYhYh_8udIZolUO620M3uoFSVllm206vvsDd7UUZT1Os-9jGOA1PlmMlNEqDq9KLyrnwJX3RQzTiKPyfRjsNfRYB59jKN0e52XWY_TAKJfgyW09RF_fvvmyeV-dnr37sDk5rTQXjaxq0xCAlvamB2WobGtOBOFgpNK14ECkFq2GWhtR09boNTCuqW65MG1TMuaH6MVet-xUAki5G2zS4JzyEKbUMcFIK9l6zQr6_B_0MkzRF3cLxSVlrawL9XJP6RJSimC6MdpBxbmjpFsu3C3pdX8uXOBnt5LT-QD9Hfr3pAWge2BnHcz_keo-fjr7vBf9DdFYuro</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>Mykoniatis, Ioannis</creator><creator>Pyrgidis, Nikolaos</creator><creator>Kalyvianakis, Dimitrios</creator><creator>Zilotis, Filimon</creator><creator>Kapoteli, Paraskevi</creator><creator>Fournaraki, Agrippina</creator><creator>Hatzichristou, Dimitrios</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TO</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3869-2888</orcidid></search><sort><creationdate>20210601</creationdate><title>Comparing two different low‐intensity shockwave therapy frequency protocols for nonbacterial chronic prostatitis/chronic pelvic pain syndrome: A two‐arm, parallel‐group randomized controlled trial</title><author>Mykoniatis, Ioannis ; Pyrgidis, Nikolaos ; Kalyvianakis, Dimitrios ; Zilotis, Filimon ; Kapoteli, Paraskevi ; Fournaraki, Agrippina ; Hatzichristou, Dimitrios</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3579-4f70ee81dfdeaf198430503ef9ac453e09c58ce4cf5418fc6e23c1c835f871193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Adverse events</topic><topic>Chronic pain</topic><topic>chronic pelvic pain syndrome</topic><topic>chronic prostatitis</topic><topic>Clinical trials</topic><topic>Extracorporeal Shockwave Therapy - methods</topic><topic>Humans</topic><topic>low‐intensity shockwave therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pain</topic><topic>Pelvic Pain - therapy</topic><topic>Prospective Studies</topic><topic>Prostate</topic><topic>Prostatitis</topic><topic>Prostatitis - therapy</topic><topic>Quality of Life</topic><topic>randomized controlled trial</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mykoniatis, Ioannis</creatorcontrib><creatorcontrib>Pyrgidis, Nikolaos</creatorcontrib><creatorcontrib>Kalyvianakis, Dimitrios</creatorcontrib><creatorcontrib>Zilotis, Filimon</creatorcontrib><creatorcontrib>Kapoteli, Paraskevi</creatorcontrib><creatorcontrib>Fournaraki, Agrippina</creatorcontrib><creatorcontrib>Hatzichristou, Dimitrios</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The Prostate</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mykoniatis, Ioannis</au><au>Pyrgidis, Nikolaos</au><au>Kalyvianakis, Dimitrios</au><au>Zilotis, Filimon</au><au>Kapoteli, Paraskevi</au><au>Fournaraki, Agrippina</au><au>Hatzichristou, Dimitrios</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparing two different low‐intensity shockwave therapy frequency protocols for nonbacterial chronic prostatitis/chronic pelvic pain syndrome: A two‐arm, parallel‐group randomized controlled trial</atitle><jtitle>The Prostate</jtitle><addtitle>Prostate</addtitle><date>2021-06-01</date><risdate>2021</risdate><volume>81</volume><issue>9</issue><spage>499</spage><epage>507</epage><pages>499-507</pages><issn>0270-4137</issn><eissn>1097-0045</eissn><abstract>Background
Despite encouraging results, the optimal low‐intensity shockwave therapy (LiST) protocol in patients with chronic prostatitis/chronic pelvic pain syndrome (CPPS) remains unknown. We conducted a two‐arm, parallel‐group, randomized controlled trial aiming to compare the efficacy and safety of six LiST sessions applied once or twice weekly.
Methods
Fifty patients with CP/CPPS type IIIb were randomly assigned to six LiST sessions once (Group A, n = 25) or twice weekly (Group B, n = 25). Both groups followed the same treatment protocol in terms of LiST application, impulses (5000/session), energy flux density (0.096 mJ/mm2) and frequency (5 Hz). Subsequently, all participants were evaluated at 1 and 3 months after completion of LiST protocol.
Results
At the follow‐up evaluations, LiST significantly improved the National Institutes of Health‐Chronic Prostatitis Symptom Index (NIH‐CPSI) total, pain and quality of life scores, as well as the International Index of Erectile Function–Erectile Domain (IIEF‐ED) in both groups (p < .001 for all measures). Comparing between the two groups, no significant differences were demonstrated in the NIH‐CPSI total, pain, urinary and quality of life scores, as well as in the International Prostate Symptom Score, IIEF–ED, and LiST‐induced pain at both follow‐up evaluations. Accordingly, no adverse events and no dropouts were observed in both groups.
Conclusion
Six sessions of LiST applied once weekly for 6 weeks or twice weekly for 3 weeks seem to be equally safe and effective in patients with CP/CPPS. Nevertheless, further studies are necessary, since LiST gradually gains its place for the management of CP/CPPS.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>33929052</pmid><doi>10.1002/pros.24119</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-3869-2888</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0270-4137 |
| ispartof | The Prostate, 2021-06, Vol.81 (9), p.499-507 |
| issn | 0270-4137 1097-0045 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2520892662 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Adult Adverse events Chronic pain chronic pelvic pain syndrome chronic prostatitis Clinical trials Extracorporeal Shockwave Therapy - methods Humans low‐intensity shockwave therapy Male Middle Aged Pain Pelvic Pain - therapy Prospective Studies Prostate Prostatitis Prostatitis - therapy Quality of Life randomized controlled trial Treatment Outcome |
| title | Comparing two different low‐intensity shockwave therapy frequency protocols for nonbacterial chronic prostatitis/chronic pelvic pain syndrome: A two‐arm, parallel‐group randomized controlled trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T10%3A18%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparing%20two%20different%20low%E2%80%90intensity%20shockwave%20therapy%20frequency%20protocols%20for%20nonbacterial%20chronic%20prostatitis/chronic%20pelvic%20pain%20syndrome:%20A%20two%E2%80%90arm,%20parallel%E2%80%90group%20randomized%20controlled%20trial&rft.jtitle=The%20Prostate&rft.au=Mykoniatis,%20Ioannis&rft.date=2021-06-01&rft.volume=81&rft.issue=9&rft.spage=499&rft.epage=507&rft.pages=499-507&rft.issn=0270-4137&rft.eissn=1097-0045&rft_id=info:doi/10.1002/pros.24119&rft_dat=%3Cproquest_cross%3E2520892662%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2523912894&rft_id=info:pmid/33929052&rfr_iscdi=true |