The long chain base unsaturation has a stronger impact on 1-deoxy(methyl)-sphingolipids biophysical properties than the structure of its C1 functional group

1-deoxy-sphingolipids, also known as atypical sphingolipids, are directly implicated in the development and progression of hereditary sensory and autonomic neuropathy type 1 and diabetes type 2. The mechanisms underlying their patho-physiological actions are yet to be elucidated. Accumulating eviden...

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Veröffentlicht in:Biochimica et biophysica acta. Biomembranes 2021-08, Vol.1863 (8), p.183628-183628, Article 183628
Hauptverfasser: Santos, Tania C.B., Saied, Essa M., Arenz, Christoph, Fedorov, Aleksander, Prieto, Manuel, Silva, Liana C.
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Sprache:eng
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