Overcoming bacteriophage insensitivity in Staphylococcus aureus using clindamycin and azithromycinat subinhibitory concentrations

Background Staphylococcus aureus is a pathogen of major concern in both acute infections and chronic conditions such as chronic rhinosinusitis (CRS). Bacteriophage (phage) therapy has recently regained interest for its potential to treat infections caused by antibiotic resistant strains including Me...

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Veröffentlicht in:	Allergy (Copenhagen) 2021-11, Vol.76 (11), p.3446-3458
Hauptverfasser:	Liu, Sha, Zhao, Yin, Hayes, Andrew, Hon, Karen, Zhang, Guimin, Bennett, Catherine, Hu, Hua, Finnie, John, Morales, Sandra, Shearwin, Linda, Psaltis, Alkis J., Shearwin, Keith, Wormald, Peter‐John, Vreugde, Sarah
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic resistance Antibiotics Azithromycin bacteriophage therapy Biofilms Chronic illnesses chronic rhinosinusitis Clindamycin Clinical isolates Drug resistance Erythromycin Methicillin Minimum inhibitory concentration Penicillin Phages Protein biosynthesis Rhinitis Rhinosinusitis S. aureus Sinusitis Staphylococcus aureus Staphylococcus infections Strains (organisms) subinhibitory
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