Safety, immunogenicity, and transplacental antibody transport of conjugated and polysaccharide pneumococcal vaccines administered to pregnant women with HIV: a multicentre randomised controlled trial

Pneumococcus remains an important cause of morbidity in pregnant women with HIV and their infants. We compared the safety and immunogenicity of PCV-10 and PPV-23 with placebo administered in pregnancy. This double-blind, multicentre, randomised controlled trial was done at eight outpatient clinics i...

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Veröffentlicht in:	The lancet HIV 2021-07, Vol.8 (7), p.e408-e419
Hauptverfasser:	Weinberg, Adriana, Muresan, Petronella, Laimon, Lauren, Pelton, Stephen I, Goldblatt, David, Canniff, Jennifer, Zimmer, Bonnie, Bone, Frederic, Newton, Lassallete, Fenton, Terence, Kiely, James, Johnson, Michael J, Joao, Esau C, Santos, Breno R, Machado, Elizabeth S, Pinto, Jorge A, Chakhtoura, Nahida, Duarte, Geraldo, Mussi-Pinhata, Marisa M, Ferreira, Adriana, Golner, Amanda, Hovind, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - therapeutic use Antibodies, Bacterial - immunology Brazil Double-Blind Method Female HIV Infections - complications HIV Infections - drug therapy HIV Infections - immunology Humans Infant Infant, Newborn Placenta - immunology Pneumococcal Infections - immunology Pneumococcal Infections - microbiology Pneumococcal Infections - prevention & control Pneumococcal Vaccines - administration & dosage Pneumococcal Vaccines - adverse effects Pregnancy Pregnant Women Streptococcus pneumoniae - immunology Young Adult
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