Comparative Analysis of the Productivity and Immunogenicity of an Attenuated Classical Swine Fever Vaccine (LOM) and an Attenuated Live Marker Classical Swine Fever Vaccine (Flc-LOM-BErns) from Laboratory to Pig Farm
Herein, we compared the productivity of pigs inoculated with one of two classical swine fever (CSF) vaccines (low virulent of Miyagi (LOM) or Flc-LOM-BErns) plus the swine erysipelothrix rhusiopathiae (SE) vaccine. The feed intake and weight increase of the pigs inoculated with Flc-LOM-BErns + SE we...
Gespeichert in:
| Veröffentlicht in: | Vaccines (Basel) 2021-04, Vol.9 (4), p.381, Article 381 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 4 |
| container_start_page | 381 |
| container_title | Vaccines (Basel) |
| container_volume | 9 |
| creator | Choe, Seeun Kim, Ki-Sun Shin, Jihye Song, Sok Park, Gyu-Nam Cha, Ra Mi Choi, Sung-Hyun Jung, Byung-Il Lee, Kyung-Won Hyun, Bang-Hun Park, Bong-Kyun An, Dong-Jun |
| description | Herein, we compared the productivity of pigs inoculated with one of two classical swine fever (CSF) vaccines (low virulent of Miyagi (LOM) or Flc-LOM-BErns) plus the swine erysipelothrix rhusiopathiae (SE) vaccine. The feed intake and weight increase of the pigs inoculated with Flc-LOM-BErns + SE were normal. However, the feed intake of the pigs inoculated with LOM + SE dropped sharply from four days post-vaccination (dpv). In addition, the slaughter date was an average of eight days later than that of the pigs inoculated with Flc-LOM-BErns + SE. All pigs inoculated with the Flc-LOM-BErns + SE vaccine were completely differentiated at 14 days against CSF E-rns antibody and at approximately 45 days against the bovine viral diarrhea virus (BVDV) E-rns antibody; the titers were maintained until slaughter. Leucopenia occurred temporarily in the LOM + SE group, but not in the Flc-LOM-BErns + SE group. Expression of tumor necrosis factor (TNF)-alpha and IFN-gamma was significantly (p < 0.05) higher in the LOM + SE group than in the mock (no vaccine) group. When conducting the same experiment on a breeding farm, the results were similar to those of the laboratory experiments. In conclusion, the biggest advantage of replacing the CSF LOM vaccine with the Flc-LOM-BErns vaccine is improved productivity. |
| doi_str_mv | 10.3390/vaccines9040381 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_webof</sourceid><recordid>TN_cdi_proquest_miscellaneous_2520867350</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_363fadc297ca48bcae80a2c61eaecca7</doaj_id><sourcerecordid>2528259942</sourcerecordid><originalsourceid>FETCH-LOGICAL-c487t-651d50be7450f39ef9b4c9925b60208854ecaaf089af68daf9f3dec6bd41b7433</originalsourceid><addsrcrecordid>eNqNks9r2zAUx83YWEvX825DsEvLyCpbtmVdBplptkDKCvvBbuZZfk7V2VIqySn5T_fnTE660PSy6SIhfd5H78E3il7H9D1jgl6sQUql0QmaUlbEz6LjhPJ8wgT7-fzR-Sg6de6WhiViVuT8ZXQUypM0T_lx9Ls0_QoseLVGMtXQbZxyxLTE3yC5tqYZZHhSfkNAN2Te94M2S9RKjlcBA02m3qMewGNDyg6cUxI68vU-dEZmuEZLfuz6JGeLL1fnW89h1WL8-wrsr8D-wzDr5CRYJh8vrXbnpLWmJwuoTRjA2A3xhlyrJZmB7V9FL1roHJ4-7CfR99nlt_JzKP80L6eLiUwL7id5FjcZrZGnGW2ZwFbUqRQiyeqcJrQoshQlQEsLAW1eNNCKljUo87pJ45qnjJ1E8523MXBbrazqwW4qA6raXhi7rMB6JTusWM5aaGQiuIS0qCVgQSGReYyAUgIPrg8712qoe2wkam-hO5Aevmh1Uy3Nuioop4yPgrMHgTV3Azpf9cpJ7DrQaAZXJVmYKecsowF9-wS9NYMNAdhSRZIJkSaButhR0hrnLLb7ZmJajSGsnoQwVLx5PMOe_xu5ALzbAfdYm9ZJhVriHgspzVPGRTLmlY664v_pUvkQZKNLM2jP_gD58_4v</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2528259942</pqid></control><display><type>article</type><title>Comparative Analysis of the Productivity and Immunogenicity of an Attenuated Classical Swine Fever Vaccine (LOM) and an Attenuated Live Marker Classical Swine Fever Vaccine (Flc-LOM-BErns) from Laboratory to Pig Farm</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>PubMed Central</source><creator>Choe, Seeun ; Kim, Ki-Sun ; Shin, Jihye ; Song, Sok ; Park, Gyu-Nam ; Cha, Ra Mi ; Choi, Sung-Hyun ; Jung, Byung-Il ; Lee, Kyung-Won ; Hyun, Bang-Hun ; Park, Bong-Kyun ; An, Dong-Jun</creator><creatorcontrib>Choe, Seeun ; Kim, Ki-Sun ; Shin, Jihye ; Song, Sok ; Park, Gyu-Nam ; Cha, Ra Mi ; Choi, Sung-Hyun ; Jung, Byung-Il ; Lee, Kyung-Won ; Hyun, Bang-Hun ; Park, Bong-Kyun ; An, Dong-Jun</creatorcontrib><description>Herein, we compared the productivity of pigs inoculated with one of two classical swine fever (CSF) vaccines (low virulent of Miyagi (LOM) or Flc-LOM-BErns) plus the swine erysipelothrix rhusiopathiae (SE) vaccine. The feed intake and weight increase of the pigs inoculated with Flc-LOM-BErns + SE were normal. However, the feed intake of the pigs inoculated with LOM + SE dropped sharply from four days post-vaccination (dpv). In addition, the slaughter date was an average of eight days later than that of the pigs inoculated with Flc-LOM-BErns + SE. All pigs inoculated with the Flc-LOM-BErns + SE vaccine were completely differentiated at 14 days against CSF E-rns antibody and at approximately 45 days against the bovine viral diarrhea virus (BVDV) E-rns antibody; the titers were maintained until slaughter. Leucopenia occurred temporarily in the LOM + SE group, but not in the Flc-LOM-BErns + SE group. Expression of tumor necrosis factor (TNF)-alpha and IFN-gamma was significantly (p < 0.05) higher in the LOM + SE group than in the mock (no vaccine) group. When conducting the same experiment on a breeding farm, the results were similar to those of the laboratory experiments. In conclusion, the biggest advantage of replacing the CSF LOM vaccine with the Flc-LOM-BErns vaccine is improved productivity.</description><identifier>ISSN: 2076-393X</identifier><identifier>EISSN: 2076-393X</identifier><identifier>DOI: 10.3390/vaccines9040381</identifier><identifier>PMID: 33924647</identifier><language>eng</language><publisher>BASEL: Mdpi</publisher><subject>Antibodies ; Body temperature ; Comparative analysis ; CSFV ; Cytokines ; Diarrhea ; DIVA ; Feeds ; Fever ; Flc-LOM-BErns ; Hog cholera ; Hogs ; Immunogenicity ; Immunology ; Laboratories ; Leukopenia ; Life Sciences & Biomedicine ; Livestock breeding ; LOM ; Medicine, Research & Experimental ; pig ; Productivity ; Proteins ; Research & Experimental Medicine ; Science & Technology ; Slaughter ; Swine ; Tumor necrosis factor-TNF ; Tumor necrosis factor-α ; Vaccines ; Viral infections ; Virulence ; Viruses ; γ-Interferon</subject><ispartof>Vaccines (Basel), 2021-04, Vol.9 (4), p.381, Article 381</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>3</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000643792000001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c487t-651d50be7450f39ef9b4c9925b60208854ecaaf089af68daf9f3dec6bd41b7433</citedby><cites>FETCH-LOGICAL-c487t-651d50be7450f39ef9b4c9925b60208854ecaaf089af68daf9f3dec6bd41b7433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070377/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070377/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,2103,2115,27928,27929,53795,53797</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33924647$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choe, Seeun</creatorcontrib><creatorcontrib>Kim, Ki-Sun</creatorcontrib><creatorcontrib>Shin, Jihye</creatorcontrib><creatorcontrib>Song, Sok</creatorcontrib><creatorcontrib>Park, Gyu-Nam</creatorcontrib><creatorcontrib>Cha, Ra Mi</creatorcontrib><creatorcontrib>Choi, Sung-Hyun</creatorcontrib><creatorcontrib>Jung, Byung-Il</creatorcontrib><creatorcontrib>Lee, Kyung-Won</creatorcontrib><creatorcontrib>Hyun, Bang-Hun</creatorcontrib><creatorcontrib>Park, Bong-Kyun</creatorcontrib><creatorcontrib>An, Dong-Jun</creatorcontrib><title>Comparative Analysis of the Productivity and Immunogenicity of an Attenuated Classical Swine Fever Vaccine (LOM) and an Attenuated Live Marker Classical Swine Fever Vaccine (Flc-LOM-BErns) from Laboratory to Pig Farm</title><title>Vaccines (Basel)</title><addtitle>VACCINES-BASEL</addtitle><addtitle>Vaccines (Basel)</addtitle><description>Herein, we compared the productivity of pigs inoculated with one of two classical swine fever (CSF) vaccines (low virulent of Miyagi (LOM) or Flc-LOM-BErns) plus the swine erysipelothrix rhusiopathiae (SE) vaccine. The feed intake and weight increase of the pigs inoculated with Flc-LOM-BErns + SE were normal. However, the feed intake of the pigs inoculated with LOM + SE dropped sharply from four days post-vaccination (dpv). In addition, the slaughter date was an average of eight days later than that of the pigs inoculated with Flc-LOM-BErns + SE. All pigs inoculated with the Flc-LOM-BErns + SE vaccine were completely differentiated at 14 days against CSF E-rns antibody and at approximately 45 days against the bovine viral diarrhea virus (BVDV) E-rns antibody; the titers were maintained until slaughter. Leucopenia occurred temporarily in the LOM + SE group, but not in the Flc-LOM-BErns + SE group. Expression of tumor necrosis factor (TNF)-alpha and IFN-gamma was significantly (p < 0.05) higher in the LOM + SE group than in the mock (no vaccine) group. When conducting the same experiment on a breeding farm, the results were similar to those of the laboratory experiments. In conclusion, the biggest advantage of replacing the CSF LOM vaccine with the Flc-LOM-BErns vaccine is improved productivity.</description><subject>Antibodies</subject><subject>Body temperature</subject><subject>Comparative analysis</subject><subject>CSFV</subject><subject>Cytokines</subject><subject>Diarrhea</subject><subject>DIVA</subject><subject>Feeds</subject><subject>Fever</subject><subject>Flc-LOM-BErns</subject><subject>Hog cholera</subject><subject>Hogs</subject><subject>Immunogenicity</subject><subject>Immunology</subject><subject>Laboratories</subject><subject>Leukopenia</subject><subject>Life Sciences & Biomedicine</subject><subject>Livestock breeding</subject><subject>LOM</subject><subject>Medicine, Research & Experimental</subject><subject>pig</subject><subject>Productivity</subject><subject>Proteins</subject><subject>Research & Experimental Medicine</subject><subject>Science & Technology</subject><subject>Slaughter</subject><subject>Swine</subject><subject>Tumor necrosis factor-TNF</subject><subject>Tumor necrosis factor-α</subject><subject>Vaccines</subject><subject>Viral infections</subject><subject>Virulence</subject><subject>Viruses</subject><subject>γ-Interferon</subject><issn>2076-393X</issn><issn>2076-393X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><sourceid>DOA</sourceid><recordid>eNqNks9r2zAUx83YWEvX825DsEvLyCpbtmVdBplptkDKCvvBbuZZfk7V2VIqySn5T_fnTE660PSy6SIhfd5H78E3il7H9D1jgl6sQUql0QmaUlbEz6LjhPJ8wgT7-fzR-Sg6de6WhiViVuT8ZXQUypM0T_lx9Ls0_QoseLVGMtXQbZxyxLTE3yC5tqYZZHhSfkNAN2Te94M2S9RKjlcBA02m3qMewGNDyg6cUxI68vU-dEZmuEZLfuz6JGeLL1fnW89h1WL8-wrsr8D-wzDr5CRYJh8vrXbnpLWmJwuoTRjA2A3xhlyrJZmB7V9FL1roHJ4-7CfR99nlt_JzKP80L6eLiUwL7id5FjcZrZGnGW2ZwFbUqRQiyeqcJrQoshQlQEsLAW1eNNCKljUo87pJ45qnjJ1E8523MXBbrazqwW4qA6raXhi7rMB6JTusWM5aaGQiuIS0qCVgQSGReYyAUgIPrg8712qoe2wkam-hO5Aevmh1Uy3Nuioop4yPgrMHgTV3Azpf9cpJ7DrQaAZXJVmYKecsowF9-wS9NYMNAdhSRZIJkSaButhR0hrnLLb7ZmJajSGsnoQwVLx5PMOe_xu5ALzbAfdYm9ZJhVriHgspzVPGRTLmlY664v_pUvkQZKNLM2jP_gD58_4v</recordid><startdate>20210413</startdate><enddate>20210413</enddate><creator>Choe, Seeun</creator><creator>Kim, Ki-Sun</creator><creator>Shin, Jihye</creator><creator>Song, Sok</creator><creator>Park, Gyu-Nam</creator><creator>Cha, Ra Mi</creator><creator>Choi, Sung-Hyun</creator><creator>Jung, Byung-Il</creator><creator>Lee, Kyung-Won</creator><creator>Hyun, Bang-Hun</creator><creator>Park, Bong-Kyun</creator><creator>An, Dong-Jun</creator><general>Mdpi</general><general>MDPI AG</general><general>MDPI</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T7</scope><scope>7XB</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20210413</creationdate><title>Comparative Analysis of the Productivity and Immunogenicity of an Attenuated Classical Swine Fever Vaccine (LOM) and an Attenuated Live Marker Classical Swine Fever Vaccine (Flc-LOM-BErns) from Laboratory to Pig Farm</title><author>Choe, Seeun ; Kim, Ki-Sun ; Shin, Jihye ; Song, Sok ; Park, Gyu-Nam ; Cha, Ra Mi ; Choi, Sung-Hyun ; Jung, Byung-Il ; Lee, Kyung-Won ; Hyun, Bang-Hun ; Park, Bong-Kyun ; An, Dong-Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c487t-651d50be7450f39ef9b4c9925b60208854ecaaf089af68daf9f3dec6bd41b7433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antibodies</topic><topic>Body temperature</topic><topic>Comparative analysis</topic><topic>CSFV</topic><topic>Cytokines</topic><topic>Diarrhea</topic><topic>DIVA</topic><topic>Feeds</topic><topic>Fever</topic><topic>Flc-LOM-BErns</topic><topic>Hog cholera</topic><topic>Hogs</topic><topic>Immunogenicity</topic><topic>Immunology</topic><topic>Laboratories</topic><topic>Leukopenia</topic><topic>Life Sciences & Biomedicine</topic><topic>Livestock breeding</topic><topic>LOM</topic><topic>Medicine, Research & Experimental</topic><topic>pig</topic><topic>Productivity</topic><topic>Proteins</topic><topic>Research & Experimental Medicine</topic><topic>Science & Technology</topic><topic>Slaughter</topic><topic>Swine</topic><topic>Tumor necrosis factor-TNF</topic><topic>Tumor necrosis factor-α</topic><topic>Vaccines</topic><topic>Viral infections</topic><topic>Virulence</topic><topic>Viruses</topic><topic>γ-Interferon</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Choe, Seeun</creatorcontrib><creatorcontrib>Kim, Ki-Sun</creatorcontrib><creatorcontrib>Shin, Jihye</creatorcontrib><creatorcontrib>Song, Sok</creatorcontrib><creatorcontrib>Park, Gyu-Nam</creatorcontrib><creatorcontrib>Cha, Ra Mi</creatorcontrib><creatorcontrib>Choi, Sung-Hyun</creatorcontrib><creatorcontrib>Jung, Byung-Il</creatorcontrib><creatorcontrib>Lee, Kyung-Won</creatorcontrib><creatorcontrib>Hyun, Bang-Hun</creatorcontrib><creatorcontrib>Park, Bong-Kyun</creatorcontrib><creatorcontrib>An, Dong-Jun</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Vaccines (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Choe, Seeun</au><au>Kim, Ki-Sun</au><au>Shin, Jihye</au><au>Song, Sok</au><au>Park, Gyu-Nam</au><au>Cha, Ra Mi</au><au>Choi, Sung-Hyun</au><au>Jung, Byung-Il</au><au>Lee, Kyung-Won</au><au>Hyun, Bang-Hun</au><au>Park, Bong-Kyun</au><au>An, Dong-Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative Analysis of the Productivity and Immunogenicity of an Attenuated Classical Swine Fever Vaccine (LOM) and an Attenuated Live Marker Classical Swine Fever Vaccine (Flc-LOM-BErns) from Laboratory to Pig Farm</atitle><jtitle>Vaccines (Basel)</jtitle><stitle>VACCINES-BASEL</stitle><addtitle>Vaccines (Basel)</addtitle><date>2021-04-13</date><risdate>2021</risdate><volume>9</volume><issue>4</issue><spage>381</spage><pages>381-</pages><artnum>381</artnum><issn>2076-393X</issn><eissn>2076-393X</eissn><abstract>Herein, we compared the productivity of pigs inoculated with one of two classical swine fever (CSF) vaccines (low virulent of Miyagi (LOM) or Flc-LOM-BErns) plus the swine erysipelothrix rhusiopathiae (SE) vaccine. The feed intake and weight increase of the pigs inoculated with Flc-LOM-BErns + SE were normal. However, the feed intake of the pigs inoculated with LOM + SE dropped sharply from four days post-vaccination (dpv). In addition, the slaughter date was an average of eight days later than that of the pigs inoculated with Flc-LOM-BErns + SE. All pigs inoculated with the Flc-LOM-BErns + SE vaccine were completely differentiated at 14 days against CSF E-rns antibody and at approximately 45 days against the bovine viral diarrhea virus (BVDV) E-rns antibody; the titers were maintained until slaughter. Leucopenia occurred temporarily in the LOM + SE group, but not in the Flc-LOM-BErns + SE group. Expression of tumor necrosis factor (TNF)-alpha and IFN-gamma was significantly (p < 0.05) higher in the LOM + SE group than in the mock (no vaccine) group. When conducting the same experiment on a breeding farm, the results were similar to those of the laboratory experiments. In conclusion, the biggest advantage of replacing the CSF LOM vaccine with the Flc-LOM-BErns vaccine is improved productivity.</abstract><cop>BASEL</cop><pub>Mdpi</pub><pmid>33924647</pmid><doi>10.3390/vaccines9040381</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2076-393X |
| ispartof | Vaccines (Basel), 2021-04, Vol.9 (4), p.381, Article 381 |
| issn | 2076-393X 2076-393X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2520867350 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Antibodies Body temperature Comparative analysis CSFV Cytokines Diarrhea DIVA Feeds Fever Flc-LOM-BErns Hog cholera Hogs Immunogenicity Immunology Laboratories Leukopenia Life Sciences & Biomedicine Livestock breeding LOM Medicine, Research & Experimental pig Productivity Proteins Research & Experimental Medicine Science & Technology Slaughter Swine Tumor necrosis factor-TNF Tumor necrosis factor-α Vaccines Viral infections Virulence Viruses γ-Interferon |
| title | Comparative Analysis of the Productivity and Immunogenicity of an Attenuated Classical Swine Fever Vaccine (LOM) and an Attenuated Live Marker Classical Swine Fever Vaccine (Flc-LOM-BErns) from Laboratory to Pig Farm |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T23%3A52%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_webof&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparative%20Analysis%20of%20the%20Productivity%20and%20Immunogenicity%20of%20an%20Attenuated%20Classical%20Swine%20Fever%20Vaccine%20(LOM)%20and%20an%20Attenuated%20Live%20Marker%20Classical%20Swine%20Fever%20Vaccine%20(Flc-LOM-BErns)%20from%20Laboratory%20to%20Pig%20Farm&rft.jtitle=Vaccines%20(Basel)&rft.au=Choe,%20Seeun&rft.date=2021-04-13&rft.volume=9&rft.issue=4&rft.spage=381&rft.pages=381-&rft.artnum=381&rft.issn=2076-393X&rft.eissn=2076-393X&rft_id=info:doi/10.3390/vaccines9040381&rft_dat=%3Cproquest_webof%3E2528259942%3C/proquest_webof%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2528259942&rft_id=info:pmid/33924647&rft_doaj_id=oai_doaj_org_article_363fadc297ca48bcae80a2c61eaecca7&rfr_iscdi=true |