Dosimetric leaf gap and leaf trailing effect in a double‐stacked multileaf collimator

Purpose To investigate (i) the dosimetric leaf gap (DLG) and the effect of the “trailing distance” between leaves from different multileaf collimator (MLC) layers in Halcyon systems and (ii) the ability of the currently available treatment planning systems (TPSs) to approximate this effect. Methods...

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Veröffentlicht in:Medical physics (Lancaster) 2021-07, Vol.48 (7), p.3413-3424
Hauptverfasser: Hernandez, Victor, Saez, Jordi, Angerud, Agnes, Cayez, Romain, Khamphan, Catherine, Nguyen, Daniel, Vieillevigne, Laure, Feygelman, Vladimir
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container_end_page 3424
container_issue 7
container_start_page 3413
container_title Medical physics (Lancaster)
container_volume 48
creator Hernandez, Victor
Saez, Jordi
Angerud, Agnes
Cayez, Romain
Khamphan, Catherine
Nguyen, Daniel
Vieillevigne, Laure
Feygelman, Vladimir
description Purpose To investigate (i) the dosimetric leaf gap (DLG) and the effect of the “trailing distance” between leaves from different multileaf collimator (MLC) layers in Halcyon systems and (ii) the ability of the currently available treatment planning systems (TPSs) to approximate this effect. Methods DICOM plans with transmission beams and sweeping gap tests were created in Python for measuring the DLG for each MLC layer independently and for both layers combined. In clinical Halcyon plans both MLC layers are interchangeably used and leaves from different layers are offset, thus forming a trailing pattern. To characterize the impact of such configuration, new tests called “trailing sweeping gaps” were designed and created where the leaves from one layer follow the leaves from the other layer at a fixed “trailing distance” t between the tips. Measurements were carried out on five Halcyons SX2 from different institutions and calculations from both the Eclipse and RayStation TPSs were compared with measurements. Results The dose accumulated during a sweeping gap delivery progressively increased with the trailing distance t. We call this “the trailing effect.” It is most pronounced for t between 0 and 5 mm, although some changes were obtained up to 20 mm. The dose variation was independent of the gap size. The measured DLG values also increased with t up to 20 mm, again with the steepest variation between 0 and 5 mm. Measured DLG values were negative at t = 0 (the leaves from both layers at the same position) but changed sign for t ≥ 1 mm, in line with the positive DLG sign usually observed with single‐layer rounded‐end MLCs. The Eclipse TPS does not explicitly model the leaf tip and, as a consequence, could not predict the dose reduction due to the trailing effect. This resulted in dose discrepancies up to +10% and −8% for the 5 mm sweeping gap and up to ±5% for the 10 mm one depending on the distance t. RayStation implements a simple model of the leaf tip that was able to approximate the trailing effect and improved the agreement with measured doses. In particular, with a prototype version of RayStation that assigned a higher transmission at the leaf tip the agreement with measured doses was within ±3% even for the 5 mm gap. The five Halcyon systems behaved very similarly but differences in the DLG around 0.2 mm were found across different treatment units and between MLC layers from the same system. The DLG for the proximal layer was consistently higher than f
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Methods DICOM plans with transmission beams and sweeping gap tests were created in Python for measuring the DLG for each MLC layer independently and for both layers combined. In clinical Halcyon plans both MLC layers are interchangeably used and leaves from different layers are offset, thus forming a trailing pattern. To characterize the impact of such configuration, new tests called “trailing sweeping gaps” were designed and created where the leaves from one layer follow the leaves from the other layer at a fixed “trailing distance” t between the tips. Measurements were carried out on five Halcyons SX2 from different institutions and calculations from both the Eclipse and RayStation TPSs were compared with measurements. Results The dose accumulated during a sweeping gap delivery progressively increased with the trailing distance t. We call this “the trailing effect.” It is most pronounced for t between 0 and 5 mm, although some changes were obtained up to 20 mm. The dose variation was independent of the gap size. The measured DLG values also increased with t up to 20 mm, again with the steepest variation between 0 and 5 mm. Measured DLG values were negative at t = 0 (the leaves from both layers at the same position) but changed sign for t ≥ 1 mm, in line with the positive DLG sign usually observed with single‐layer rounded‐end MLCs. The Eclipse TPS does not explicitly model the leaf tip and, as a consequence, could not predict the dose reduction due to the trailing effect. This resulted in dose discrepancies up to +10% and −8% for the 5 mm sweeping gap and up to ±5% for the 10 mm one depending on the distance t. RayStation implements a simple model of the leaf tip that was able to approximate the trailing effect and improved the agreement with measured doses. In particular, with a prototype version of RayStation that assigned a higher transmission at the leaf tip the agreement with measured doses was within ±3% even for the 5 mm gap. The five Halcyon systems behaved very similarly but differences in the DLG around 0.2 mm were found across different treatment units and between MLC layers from the same system. The DLG for the proximal layer was consistently higher than for the distal layer, with differences ranging between 0.10 mm and 0.24 mm. Conclusions The trailing distance between the leaves from different layers substantially affected the doses delivered by sweeping gaps and the measured DLG values. Stacked MLCs introduce a new level of complexity in TPSs, which ideally need to implement an explicit model of the leaf tip in order to reproduce the trailing effect. Dynamic tests called “trailing sweeping gaps” were designed that are useful for characterizing and commissioning dual‐layer MLC systems.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1002/mp.14914</identifier><identifier>PMID: 33932237</identifier><language>eng</language><publisher>United States</publisher><subject>dosimetric leaf gap ; Halcyon ; MLC model ; stacked MLC ; trailing effect</subject><ispartof>Medical physics (Lancaster), 2021-07, Vol.48 (7), p.3413-3424</ispartof><rights>2021 American Association of Physicists in Medicine</rights><rights>2021 American Association of Physicists in Medicine.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3874-fe99214a1199887647059979d008c3f4de5a6c84ce05f5652087fd58a3fb0e263</citedby><cites>FETCH-LOGICAL-c3874-fe99214a1199887647059979d008c3f4de5a6c84ce05f5652087fd58a3fb0e263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmp.14914$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmp.14914$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33932237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hernandez, Victor</creatorcontrib><creatorcontrib>Saez, Jordi</creatorcontrib><creatorcontrib>Angerud, Agnes</creatorcontrib><creatorcontrib>Cayez, Romain</creatorcontrib><creatorcontrib>Khamphan, Catherine</creatorcontrib><creatorcontrib>Nguyen, Daniel</creatorcontrib><creatorcontrib>Vieillevigne, Laure</creatorcontrib><creatorcontrib>Feygelman, Vladimir</creatorcontrib><title>Dosimetric leaf gap and leaf trailing effect in a double‐stacked multileaf collimator</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Purpose To investigate (i) the dosimetric leaf gap (DLG) and the effect of the “trailing distance” between leaves from different multileaf collimator (MLC) layers in Halcyon systems and (ii) the ability of the currently available treatment planning systems (TPSs) to approximate this effect. Methods DICOM plans with transmission beams and sweeping gap tests were created in Python for measuring the DLG for each MLC layer independently and for both layers combined. In clinical Halcyon plans both MLC layers are interchangeably used and leaves from different layers are offset, thus forming a trailing pattern. To characterize the impact of such configuration, new tests called “trailing sweeping gaps” were designed and created where the leaves from one layer follow the leaves from the other layer at a fixed “trailing distance” t between the tips. Measurements were carried out on five Halcyons SX2 from different institutions and calculations from both the Eclipse and RayStation TPSs were compared with measurements. Results The dose accumulated during a sweeping gap delivery progressively increased with the trailing distance t. We call this “the trailing effect.” It is most pronounced for t between 0 and 5 mm, although some changes were obtained up to 20 mm. The dose variation was independent of the gap size. The measured DLG values also increased with t up to 20 mm, again with the steepest variation between 0 and 5 mm. Measured DLG values were negative at t = 0 (the leaves from both layers at the same position) but changed sign for t ≥ 1 mm, in line with the positive DLG sign usually observed with single‐layer rounded‐end MLCs. The Eclipse TPS does not explicitly model the leaf tip and, as a consequence, could not predict the dose reduction due to the trailing effect. This resulted in dose discrepancies up to +10% and −8% for the 5 mm sweeping gap and up to ±5% for the 10 mm one depending on the distance t. RayStation implements a simple model of the leaf tip that was able to approximate the trailing effect and improved the agreement with measured doses. In particular, with a prototype version of RayStation that assigned a higher transmission at the leaf tip the agreement with measured doses was within ±3% even for the 5 mm gap. The five Halcyon systems behaved very similarly but differences in the DLG around 0.2 mm were found across different treatment units and between MLC layers from the same system. The DLG for the proximal layer was consistently higher than for the distal layer, with differences ranging between 0.10 mm and 0.24 mm. Conclusions The trailing distance between the leaves from different layers substantially affected the doses delivered by sweeping gaps and the measured DLG values. Stacked MLCs introduce a new level of complexity in TPSs, which ideally need to implement an explicit model of the leaf tip in order to reproduce the trailing effect. Dynamic tests called “trailing sweeping gaps” were designed that are useful for characterizing and commissioning dual‐layer MLC systems.</description><subject>dosimetric leaf gap</subject><subject>Halcyon</subject><subject>MLC model</subject><subject>stacked MLC</subject><subject>trailing effect</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kMtOwzAQRS0EoqUg8QXISzYp41cSL1F5SkWwALGMXMeuDM6DOBHqjk_gG_kS0qbAitVopHOPZi5CxwSmBICeFfWUcEn4DhpTnrCIU5C7aAwgeUQ5iBE6COEFAGImYB-NGJOMUpaM0fNFFVxh2sZp7I2yeKlqrMp8WNpGOe_KJTbWGt1iV2KF86pbePP18RlapV9NjovOt27D68p7V6i2ag7RnlU-mKPtnKCnq8vH2U00v7--nZ3PI83ShEfWSEkJV4RImaZJzBMQUiYyB0g1szw3QsU65dqAsCIWFNLE5iJVzC7A0JhN0OngrZvqrTOhzQoXtPFelabqQkbXEREzlv6huqlCaIzN6qY_tlllBLJ1jVlRZ5sae_Rka-0Whcl_wZ_eeiAagPf-8dW_ouzuYRB-A0Y8evo</recordid><startdate>202107</startdate><enddate>202107</enddate><creator>Hernandez, Victor</creator><creator>Saez, Jordi</creator><creator>Angerud, Agnes</creator><creator>Cayez, Romain</creator><creator>Khamphan, Catherine</creator><creator>Nguyen, Daniel</creator><creator>Vieillevigne, Laure</creator><creator>Feygelman, Vladimir</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202107</creationdate><title>Dosimetric leaf gap and leaf trailing effect in a double‐stacked multileaf collimator</title><author>Hernandez, Victor ; Saez, Jordi ; Angerud, Agnes ; Cayez, Romain ; Khamphan, Catherine ; Nguyen, Daniel ; Vieillevigne, Laure ; Feygelman, Vladimir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3874-fe99214a1199887647059979d008c3f4de5a6c84ce05f5652087fd58a3fb0e263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>dosimetric leaf gap</topic><topic>Halcyon</topic><topic>MLC model</topic><topic>stacked MLC</topic><topic>trailing effect</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hernandez, Victor</creatorcontrib><creatorcontrib>Saez, Jordi</creatorcontrib><creatorcontrib>Angerud, Agnes</creatorcontrib><creatorcontrib>Cayez, Romain</creatorcontrib><creatorcontrib>Khamphan, Catherine</creatorcontrib><creatorcontrib>Nguyen, Daniel</creatorcontrib><creatorcontrib>Vieillevigne, Laure</creatorcontrib><creatorcontrib>Feygelman, Vladimir</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hernandez, Victor</au><au>Saez, Jordi</au><au>Angerud, Agnes</au><au>Cayez, Romain</au><au>Khamphan, Catherine</au><au>Nguyen, Daniel</au><au>Vieillevigne, Laure</au><au>Feygelman, Vladimir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dosimetric leaf gap and leaf trailing effect in a double‐stacked multileaf collimator</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2021-07</date><risdate>2021</risdate><volume>48</volume><issue>7</issue><spage>3413</spage><epage>3424</epage><pages>3413-3424</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><abstract>Purpose To investigate (i) the dosimetric leaf gap (DLG) and the effect of the “trailing distance” between leaves from different multileaf collimator (MLC) layers in Halcyon systems and (ii) the ability of the currently available treatment planning systems (TPSs) to approximate this effect. Methods DICOM plans with transmission beams and sweeping gap tests were created in Python for measuring the DLG for each MLC layer independently and for both layers combined. In clinical Halcyon plans both MLC layers are interchangeably used and leaves from different layers are offset, thus forming a trailing pattern. To characterize the impact of such configuration, new tests called “trailing sweeping gaps” were designed and created where the leaves from one layer follow the leaves from the other layer at a fixed “trailing distance” t between the tips. Measurements were carried out on five Halcyons SX2 from different institutions and calculations from both the Eclipse and RayStation TPSs were compared with measurements. Results The dose accumulated during a sweeping gap delivery progressively increased with the trailing distance t. We call this “the trailing effect.” It is most pronounced for t between 0 and 5 mm, although some changes were obtained up to 20 mm. The dose variation was independent of the gap size. The measured DLG values also increased with t up to 20 mm, again with the steepest variation between 0 and 5 mm. Measured DLG values were negative at t = 0 (the leaves from both layers at the same position) but changed sign for t ≥ 1 mm, in line with the positive DLG sign usually observed with single‐layer rounded‐end MLCs. The Eclipse TPS does not explicitly model the leaf tip and, as a consequence, could not predict the dose reduction due to the trailing effect. This resulted in dose discrepancies up to +10% and −8% for the 5 mm sweeping gap and up to ±5% for the 10 mm one depending on the distance t. RayStation implements a simple model of the leaf tip that was able to approximate the trailing effect and improved the agreement with measured doses. In particular, with a prototype version of RayStation that assigned a higher transmission at the leaf tip the agreement with measured doses was within ±3% even for the 5 mm gap. The five Halcyon systems behaved very similarly but differences in the DLG around 0.2 mm were found across different treatment units and between MLC layers from the same system. The DLG for the proximal layer was consistently higher than for the distal layer, with differences ranging between 0.10 mm and 0.24 mm. Conclusions The trailing distance between the leaves from different layers substantially affected the doses delivered by sweeping gaps and the measured DLG values. Stacked MLCs introduce a new level of complexity in TPSs, which ideally need to implement an explicit model of the leaf tip in order to reproduce the trailing effect. Dynamic tests called “trailing sweeping gaps” were designed that are useful for characterizing and commissioning dual‐layer MLC systems.</abstract><cop>United States</cop><pmid>33932237</pmid><doi>10.1002/mp.14914</doi><tpages>12</tpages></addata></record>
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subjects dosimetric leaf gap
Halcyon
MLC model
stacked MLC
trailing effect
title Dosimetric leaf gap and leaf trailing effect in a double‐stacked multileaf collimator
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