LncRNA EWSAT1 Regulates the Tumorigenesis of NSCLC as a ceRNA by Modulating miR-330-5p/ITGA5 Axis

The aim of the study is to investigate how lncRNA EWSAT1 regulates the tumorigenesis of non-small cell lung cancer (NSCLC) as a ceRNA by modulating miR-330-5p/ITGA5 axis. qRT-PCR was conducted to evaluate the expression of EWSAT1 in NSCLC tissue. Then, A549 cells were selected and divided into Blank...

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Veröffentlicht in:	Biochemical genetics 2021-12, Vol.59 (6), p.1441-1456
Hauptverfasser:	Cui, Su, Yang, Chun-Lu, Chen, Dong-Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Animals Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Carcinogenesis - genetics Carcinoma, Non-Small-Cell Lung - genetics Caspase-3 Cell growth Cell Proliferation Gelatinase A Gelatinase B Gene Expression Regulation, Neoplastic Heterografts Human Genetics Humans Inhibitors Integrins Lung cancer Lung Neoplasms - genetics Lymph nodes Medical Microbiology Metastases Mice Mice, Nude MicroRNAs - genetics Non-small cell lung carcinoma Original Article Reporter gene RNA, Long Noncoding - genetics RNA-Binding Protein EWS Signal Transduction Small cell lung carcinoma Transfection Tumorigenesis Tumors Xenografts Xenotransplantation Zoology
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