Real-world genetic testing patterns in metastatic castration-resistant prostate cancer

To assess the patterns of genetic testing for homologous recombination repair mutations in patients with metastatic castration-resistant prostate cancer (mCRPC) pre-PARP inhibitors approval. mCRPC patients were selected in an oncology electronic medical records database. Patterns and predictors of t...

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Veröffentlicht in:	Future oncology (London, England) England), 2021-08, Vol.17 (22), p.2907-2921
Hauptverfasser:	Shore, Neal, Ionescu-Ittu, Raluca, Yang, Lingfeng, Laliberté, François, Mahendran, Malena, Lejeune, Dominique, Yu, Louise, Burgents, Joseph, Duh, Mei Sheng, Ghate, Sameer R
Format:	Artikel
Sprache:	eng
Schlagworte:	Academic Medical Centers Aged Aged, 80 and over Biomarkers, Tumor - antagonists & inhibitors Biomarkers, Tumor - genetics Cancer Care Facilities - statistics & numerical data Clinical Decision-Making - methods Community Health Centers - statistics & numerical data DNA Repair genetic testing Genetic Testing - statistics & numerical data HRR gene alterations Humans Male metastatic castration-resistant prostate cancer Middle Aged PARP inhibitors Poly(ADP-ribose) Polymerase Inhibitors - pharmacology Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use Practice Patterns, Physicians' - statistics & numerical data Precision Medicine - methods Precision Medicine - statistics & numerical data predictors Prostatic Neoplasms, Castration-Resistant - diagnosis Prostatic Neoplasms, Castration-Resistant - drug therapy Prostatic Neoplasms, Castration-Resistant - genetics Prostatic Neoplasms, Castration-Resistant - pathology real world
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