Treatment response assessment following transarterial radioembolization for hepatocellular carcinoma
Transarterial radioembolization with yttrium-90 microspheres is an established therapy for hepatocellular carcinoma. Post-procedural imaging is important for the assessment of both treatment response and procedural complications. A variety of challenging treatment-specific imaging phenomena complica...
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Veröffentlicht in: | Abdominal imaging 2021-08, Vol.46 (8), p.3596-3614 |
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creator | Alem, Zersenay Murray, Timothy E. Egri, Csilla Chung, John Liu, David Elsayes, Khaled M. Chang, Silvia D. Harris, Alison |
description | Transarterial radioembolization with yttrium-90 microspheres is an established therapy for hepatocellular carcinoma. Post-procedural imaging is important for the assessment of both treatment response and procedural complications. A variety of challenging treatment-specific imaging phenomena complicate imaging assessment, such as changes in tumoral size, tumoral and peritumoral enhancement, and extrahepatic complications. A review of the procedural steps, emerging variations, and timelines for post-treatment tumoral and extra-tumoral imaging changes are presented, which may aid the reporting radiologist in the interpretation of post-procedural imaging. Furthermore, a description of post-procedural complications and their significance is provided. |
doi_str_mv | 10.1007/s00261-021-03095-8 |
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Post-procedural imaging is important for the assessment of both treatment response and procedural complications. A variety of challenging treatment-specific imaging phenomena complicate imaging assessment, such as changes in tumoral size, tumoral and peritumoral enhancement, and extrahepatic complications. A review of the procedural steps, emerging variations, and timelines for post-treatment tumoral and extra-tumoral imaging changes are presented, which may aid the reporting radiologist in the interpretation of post-procedural imaging. 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Post-procedural imaging is important for the assessment of both treatment response and procedural complications. A variety of challenging treatment-specific imaging phenomena complicate imaging assessment, such as changes in tumoral size, tumoral and peritumoral enhancement, and extrahepatic complications. A review of the procedural steps, emerging variations, and timelines for post-treatment tumoral and extra-tumoral imaging changes are presented, which may aid the reporting radiologist in the interpretation of post-procedural imaging. Furthermore, a description of post-procedural complications and their significance is provided.</description><subject>Brachytherapy</subject><subject>Carcinoma, Hepatocellular - diagnostic imaging</subject><subject>Carcinoma, Hepatocellular - radiotherapy</subject><subject>Complications</subject><subject>Embolization, Therapeutic</subject><subject>Gastroenterology</subject><subject>Hepatocellular carcinoma</subject><subject>Hepatology</subject><subject>Humans</subject><subject>Imaging</subject><subject>Liver cancer</subject><subject>Liver Neoplasms - diagnostic imaging</subject><subject>Liver Neoplasms - radiotherapy</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Microspheres</subject><subject>Radiology</subject><subject>Special Section: HCC Treatment</subject><subject>Treatment Outcome</subject><subject>Yttrium</subject><subject>Yttrium isotopes</subject><subject>Yttrium Radioisotopes - therapeutic use</subject><issn>2366-004X</issn><issn>2366-0058</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU1LxDAQhoMoKuof8CAFL16qk6Tpx1EWv0DwsoK3kLYTrbTJmmkR_fVmd3UFDzIMEybPvBnyMnbM4ZwDFBcEIHKegogpoVJpucX2hczzFECV25tz9rTHjoheAYDninOhdtmelBXEEPusnQc044BuTALSwjvCxBAh0apnfd_79849J2MwjkwYMXSmT4JpO49D7fvu04ydd5EMyQsuzOgb7PupNyFpTGg65wdzyHas6QmPvusBe7y-ms9u0_uHm7vZ5X3ayEKNKYdM5FYYsBJsjUVdYVvbgiuJmVQqs7mVmHMlyoYLKUteZ7lsLVZNISxiIw_Y2Vp3EfzbhDTqoaPlOsahn0gLxSvJBc9kRE__oK9-Ci5uFyklClWJTERKrKkmeKKAVi9CN5jwoTnopQ16bYOONuiVDbqMQyff0lM9YLsZ-fn0CMg1QPHKPWP4ffsf2S_r65Sh</recordid><startdate>20210801</startdate><enddate>20210801</enddate><creator>Alem, Zersenay</creator><creator>Murray, Timothy E.</creator><creator>Egri, Csilla</creator><creator>Chung, John</creator><creator>Liu, David</creator><creator>Elsayes, Khaled M.</creator><creator>Chang, Silvia D.</creator><creator>Harris, Alison</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>JQ2</scope><scope>K7-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6195-6127</orcidid></search><sort><creationdate>20210801</creationdate><title>Treatment response assessment following transarterial radioembolization for hepatocellular carcinoma</title><author>Alem, Zersenay ; Murray, Timothy E. ; Egri, Csilla ; Chung, John ; Liu, David ; Elsayes, Khaled M. ; Chang, Silvia D. ; Harris, Alison</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-10426f2a0f30fbe7b9edbf7153e43554f6f3e61528c123381b463dfe9c72feec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Brachytherapy</topic><topic>Carcinoma, Hepatocellular - diagnostic imaging</topic><topic>Carcinoma, Hepatocellular - radiotherapy</topic><topic>Complications</topic><topic>Embolization, Therapeutic</topic><topic>Gastroenterology</topic><topic>Hepatocellular carcinoma</topic><topic>Hepatology</topic><topic>Humans</topic><topic>Imaging</topic><topic>Liver cancer</topic><topic>Liver Neoplasms - diagnostic imaging</topic><topic>Liver Neoplasms - radiotherapy</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Microspheres</topic><topic>Radiology</topic><topic>Special Section: HCC Treatment</topic><topic>Treatment Outcome</topic><topic>Yttrium</topic><topic>Yttrium isotopes</topic><topic>Yttrium Radioisotopes - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alem, Zersenay</creatorcontrib><creatorcontrib>Murray, Timothy E.</creatorcontrib><creatorcontrib>Egri, Csilla</creatorcontrib><creatorcontrib>Chung, John</creatorcontrib><creatorcontrib>Liu, David</creatorcontrib><creatorcontrib>Elsayes, Khaled M.</creatorcontrib><creatorcontrib>Chang, Silvia D.</creatorcontrib><creatorcontrib>Harris, Alison</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Computer Science Collection</collection><collection>Computer Science Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Abdominal imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alem, Zersenay</au><au>Murray, Timothy E.</au><au>Egri, Csilla</au><au>Chung, John</au><au>Liu, David</au><au>Elsayes, Khaled M.</au><au>Chang, Silvia D.</au><au>Harris, Alison</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment response assessment following transarterial radioembolization for hepatocellular carcinoma</atitle><jtitle>Abdominal imaging</jtitle><stitle>Abdom Radiol</stitle><addtitle>Abdom Radiol (NY)</addtitle><date>2021-08-01</date><risdate>2021</risdate><volume>46</volume><issue>8</issue><spage>3596</spage><epage>3614</epage><pages>3596-3614</pages><issn>2366-004X</issn><eissn>2366-0058</eissn><abstract>Transarterial radioembolization with yttrium-90 microspheres is an established therapy for hepatocellular carcinoma. Post-procedural imaging is important for the assessment of both treatment response and procedural complications. A variety of challenging treatment-specific imaging phenomena complicate imaging assessment, such as changes in tumoral size, tumoral and peritumoral enhancement, and extrahepatic complications. A review of the procedural steps, emerging variations, and timelines for post-treatment tumoral and extra-tumoral imaging changes are presented, which may aid the reporting radiologist in the interpretation of post-procedural imaging. Furthermore, a description of post-procedural complications and their significance is provided.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33909092</pmid><doi>10.1007/s00261-021-03095-8</doi><tpages>19</tpages><orcidid>https://orcid.org/0000-0001-6195-6127</orcidid></addata></record> |
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subjects | Brachytherapy Carcinoma, Hepatocellular - diagnostic imaging Carcinoma, Hepatocellular - radiotherapy Complications Embolization, Therapeutic Gastroenterology Hepatocellular carcinoma Hepatology Humans Imaging Liver cancer Liver Neoplasms - diagnostic imaging Liver Neoplasms - radiotherapy Medicine Medicine & Public Health Microspheres Radiology Special Section: HCC Treatment Treatment Outcome Yttrium Yttrium isotopes Yttrium Radioisotopes - therapeutic use |
title | Treatment response assessment following transarterial radioembolization for hepatocellular carcinoma |
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