A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration

•We have developed a useful model to study endogenous regeneration in RGCs.•This is a useful model to investigate changes within the lesion microenvironment.•Endogenous regenerative ability of RGCs can be improved with less inhibitors.•Improving permissive properties in lesion is helpful for repair...

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Veröffentlicht in:	Neuroscience 2021-06, Vol.465, p.71-84
Hauptverfasser:	Zhang, Si, Liu, Bo, Zhu, Hui, Jin, Haochen, Gong, Zan, Qiu, Haijun, Xu, Mingna, Chen, Mei, Nan, Kaihui, Wu, Wencan
Format:	Artikel
Sprache:	eng
Schlagworte:	chondroitin sulfate proteoglycans microenvironment myelin optic nerve crush optic nerve regeneration
Online-Zugang:	Volltext
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