Characteristics and outcome of BRCA mutated epithelial ovarian cancer patients in Italy: A retrospective multicenter study (MITO 21)

Around 15% of epithelial ovarian cancer (EOC) patients (pts) harbor a germline BRCA1 or 2 mutation, showing different features than BRCA wild-type pts. The clinical and pathological features of an Italian BRCA mutated EOC cohort were described. We retrospectively analyzed clinical, pathological and...

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Veröffentlicht in:	Gynecologic oncology 2021-06, Vol.161 (3), p.755-761
Hauptverfasser:	Artioli, Grazia, Giannone, Gaia, Valabrega, Giorgio, Maggiorotto, Furio, Genta, Sofia, Pignata, Sandro, Lorusso, Domenica, Cormio, Gennaro, Scalone, Simona, Nicoletto, Maria Ornella, Greco, Filippo, Rossi, Emanuela, Spagnoletti, Ilaria, De Giorgi, Ugo, Orditura, Michele, Mosconi, Anna Maria, Kardhashi, Anila, Bogliolo, Stefano, Borgato, Lucia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over BRCA 1 and BRCA 2 genes BRCA1 Protein - genetics Carcinoma, Ovarian Epithelial - genetics Carcinoma, Ovarian Epithelial - mortality Carcinoma, Ovarian Epithelial - pathology Demography Female Genetic Predisposition to Disease Humans Italy Metachronous breast cancer Middle Aged Neoplasm Staging Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - mortality Ovarian Neoplasms - pathology Progression-Free Survival Retrospective Studies
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