Influence of the gallate moiety on the interactions between green tea polyphenols and lipid membranes elucidated by molecular dynamics simulations

Previous studies suggested that naturally occurring EGCG primarily acted on the bacterial cell membrane then damaged the membrane and the gallate moiety in EGCG was very important to its anti-bacterial activity. However, the detailed mechanisms were still poorly understood. In this paper, EGCG and E...

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Veröffentlicht in:	Biophysical chemistry 2021-07, Vol.274, p.106592-106592, Article 106592
Hauptverfasser:	Nie, Rong-zu, Dang, Mei-zhu, Ge, Zhen-zhen, Huo, Yin-qiang, Yu, Bo, Tang, Shang-wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-bacterial activity EGC EGCG Gallate moiety Lipid bilayer Molecular dynamics simulation
Online-Zugang:	Volltext
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