Chemerin causes lipid metabolic imbalance and induces passive lipid accumulation in human hepatoma cell line via the receptor GPR1

Chemerin is abundant in patients with high body mass index and metabolic syndrome possibly due to its activation in adipogenesis and glucose intolerance. It has reported that sera chemerin is positively associated with fatty liver with little known underlying mechanisms. Our aim is to study the role...

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Veröffentlicht in:	Life sciences (1973) 2021-08, Vol.278, p.119530-119530, Article 119530
Hauptverfasser:	Zhu, Lin, Huang, Jianfeng, Wang, Yi, Yang, Zaiqing, Chen, Xiaodong
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Adipogenesis Antibodies Assaying Bioaccumulation Body mass Body mass index Body size Chemerin Down-regulation Fatty acid oxidation Fatty acids Fatty liver Gene expression Genes Glucose tolerance GPR1 Hepatocyte Hepatoma Inflammation Insulin Intolerance Lipid metabolism Lipids Lipogenesis Metabolic disorders Metabolic syndrome Metabolism Neutralization Overexpression Proteins Sterol regulatory element-binding protein
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