Exercise tolerance and quality of life in patients with known or suspected coronary artery disease
Background Coronary artery disease (CAD) is known to impact on patients’ physical and mental health. The relationship between performance on treadmill exercise tolerance test (ETT) and health-related quality of life (HRQL)has never been specifically investigated in the setting of CAD. Methods Consec...
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| Veröffentlicht in: | Quality of life research 2021-09, Vol.30 (9), p.2541-2550 |
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| creator | Katsi, Vasiliki Georgiopoulos, Georgios Mitropoulou, Panagiota Kontoangelos, Konstantinos Kollia, Zoi Tzavara, Chara Soulis, Dimitrios Toutouzas, Konstantinos Oikonomou, Dimitrios Aimo, Alberto Tsioufis, Konstantinos |
| description | Background
Coronary artery disease (CAD) is known to impact on patients’ physical and mental health. The relationship between performance on treadmill exercise tolerance test (ETT) and health-related quality of life (HRQL)has never been specifically investigated in the setting of CAD.
Methods
Consecutive patients undergoing an ETT with the Bruce protocol during a diagnostic workup for CAD (
n
= 1,631, age 55 ± 12 years) were evaluated. Exercise-related indices were recorded. Detailed information on cardiovascular risk factors and past medical history were obtained. HRQLwas assessed with the use of the validated 36-Item Short Form Survey (SF-36) questionnaire.
Results
Increasing age and the presence of cardiovascular risk factors and comorbidities correlated with lower scores on the physical and mental health component of SF-36(all
P
|
| doi_str_mv | 10.1007/s11136-021-02844-y |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2518225027</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>48751594</jstor_id><sourcerecordid>48751594</sourcerecordid><originalsourceid>FETCH-LOGICAL-c397t-9c9412f76d241df7dc50fc11d67ae1a2480a4483cd919408bd48e968fb9d9ce63</originalsourceid><addsrcrecordid>eNp9kUuPFCEUhYnROD2tf8BEQ-JmNqVcoChYmsn4SCZxo2tCwy2tthp6gMpM_3vRGsfEhQtyF3zn3Mch5AWwN8DY8LYAgFAd49CelrI7PSIb6AfRcSXNY7JhRvHOCCnOyHkpe8aYNow_JWdCaCOMgA3ZXd1h9lNBWtOM2UWP1MVAbxY3T_VE00jnaUQ6RXp0dcJYC72d6nf6I6bbSFOmZSlH9BUD9Smn6PKJulyxldBsXcFn5Mno5oLP7-uWfH1_9eXyY3f9-cOny3fXnRdmqJ3xRgIfBxW4hDAOwfds9ABBDQ7BcamZk1ILHwwYyfQuSI1G6XFngvGoxJZcrL7HnG4WLNUepuJxnl3EtBTLe9Cc94wPDX39D7pPS45tukYpBVLJdtot4Svlcyol42iPeTq0BS0w-ysBuyZgWwL2dwL21ESv7q2X3QHDg-TPyRsgVqC0r_gN89_e_7V9uar2pab84Cr10ENvpPgJI3Kbzw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2566146411</pqid></control><display><type>article</type><title>Exercise tolerance and quality of life in patients with known or suspected coronary artery disease</title><source>Springer Nature - Complete Springer Journals</source><creator>Katsi, Vasiliki ; Georgiopoulos, Georgios ; Mitropoulou, Panagiota ; Kontoangelos, Konstantinos ; Kollia, Zoi ; Tzavara, Chara ; Soulis, Dimitrios ; Toutouzas, Konstantinos ; Oikonomou, Dimitrios ; Aimo, Alberto ; Tsioufis, Konstantinos</creator><creatorcontrib>Katsi, Vasiliki ; Georgiopoulos, Georgios ; Mitropoulou, Panagiota ; Kontoangelos, Konstantinos ; Kollia, Zoi ; Tzavara, Chara ; Soulis, Dimitrios ; Toutouzas, Konstantinos ; Oikonomou, Dimitrios ; Aimo, Alberto ; Tsioufis, Konstantinos</creatorcontrib><description>Background
Coronary artery disease (CAD) is known to impact on patients’ physical and mental health. The relationship between performance on treadmill exercise tolerance test (ETT) and health-related quality of life (HRQL)has never been specifically investigated in the setting of CAD.
Methods
Consecutive patients undergoing an ETT with the Bruce protocol during a diagnostic workup for CAD (
n
= 1,631, age 55 ± 12 years) were evaluated. Exercise-related indices were recorded. Detailed information on cardiovascular risk factors and past medical history were obtained. HRQLwas assessed with the use of the validated 36-Item Short Form Survey (SF-36) questionnaire.
Results
Increasing age and the presence of cardiovascular risk factors and comorbidities correlated with lower scores on the physical and mental health component of SF-36(all
P
< 0.05). Subjects with arrhythmias during exercise and slow recovery of systolic blood pressure had lower scores on the physical health indices or the Social Role Functioning component (
P
< 0.05). Achieved target heart rate and good exercise tolerance were independently associated with better scores of the physical and mental health domains of SF-36 and overall HRQLscores (β = 0.05 for target HR and PCS-36, β = 1.86 and β = 1.66 per increasing stage of exercise tolerance and PCS-36 and MCS-36, respectively,
P
< 0.001 for all associations). Ischemic ECG changes were associated with worse scores on Physical Functioning (β = − 3.2,
P
= 0.02) and Bodily Pain (β = − 4.55,
P
= 0.026).
Conclusion
ETT parameters are associated with HRQL indices in patients evaluated for possible CAD. Physical conditioning may increase patient well-being and could serve as a complementary target in conjunction with cardiovascular drug therapy.</description><identifier>ISSN: 0962-9343</identifier><identifier>EISSN: 1573-2649</identifier><identifier>DOI: 10.1007/s11136-021-02844-y</identifier><identifier>PMID: 33893931</identifier><language>eng</language><publisher>Cham: Springer Science + Business Media</publisher><subject>Cardiovascular disease ; CLINICAL AND POLICY APPLICATIONS ; Coronary vessels ; Exercise ; Medicine ; Medicine & Public Health ; Mental health ; Public Health ; Quality of life ; Quality of Life Research ; Sociology ; Vein & artery diseases ; Well being</subject><ispartof>Quality of life research, 2021-09, Vol.30 (9), p.2541-2550</ispartof><rights>The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021</rights><rights>The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c397t-9c9412f76d241df7dc50fc11d67ae1a2480a4483cd919408bd48e968fb9d9ce63</citedby><cites>FETCH-LOGICAL-c397t-9c9412f76d241df7dc50fc11d67ae1a2480a4483cd919408bd48e968fb9d9ce63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11136-021-02844-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11136-021-02844-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33893931$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Katsi, Vasiliki</creatorcontrib><creatorcontrib>Georgiopoulos, Georgios</creatorcontrib><creatorcontrib>Mitropoulou, Panagiota</creatorcontrib><creatorcontrib>Kontoangelos, Konstantinos</creatorcontrib><creatorcontrib>Kollia, Zoi</creatorcontrib><creatorcontrib>Tzavara, Chara</creatorcontrib><creatorcontrib>Soulis, Dimitrios</creatorcontrib><creatorcontrib>Toutouzas, Konstantinos</creatorcontrib><creatorcontrib>Oikonomou, Dimitrios</creatorcontrib><creatorcontrib>Aimo, Alberto</creatorcontrib><creatorcontrib>Tsioufis, Konstantinos</creatorcontrib><title>Exercise tolerance and quality of life in patients with known or suspected coronary artery disease</title><title>Quality of life research</title><addtitle>Qual Life Res</addtitle><addtitle>Qual Life Res</addtitle><description>Background
Coronary artery disease (CAD) is known to impact on patients’ physical and mental health. The relationship between performance on treadmill exercise tolerance test (ETT) and health-related quality of life (HRQL)has never been specifically investigated in the setting of CAD.
Methods
Consecutive patients undergoing an ETT with the Bruce protocol during a diagnostic workup for CAD (
n
= 1,631, age 55 ± 12 years) were evaluated. Exercise-related indices were recorded. Detailed information on cardiovascular risk factors and past medical history were obtained. HRQLwas assessed with the use of the validated 36-Item Short Form Survey (SF-36) questionnaire.
Results
Increasing age and the presence of cardiovascular risk factors and comorbidities correlated with lower scores on the physical and mental health component of SF-36(all
P
< 0.05). Subjects with arrhythmias during exercise and slow recovery of systolic blood pressure had lower scores on the physical health indices or the Social Role Functioning component (
P
< 0.05). Achieved target heart rate and good exercise tolerance were independently associated with better scores of the physical and mental health domains of SF-36 and overall HRQLscores (β = 0.05 for target HR and PCS-36, β = 1.86 and β = 1.66 per increasing stage of exercise tolerance and PCS-36 and MCS-36, respectively,
P
< 0.001 for all associations). Ischemic ECG changes were associated with worse scores on Physical Functioning (β = − 3.2,
P
= 0.02) and Bodily Pain (β = − 4.55,
P
= 0.026).
Conclusion
ETT parameters are associated with HRQL indices in patients evaluated for possible CAD. Physical conditioning may increase patient well-being and could serve as a complementary target in conjunction with cardiovascular drug therapy.</description><subject>Cardiovascular disease</subject><subject>CLINICAL AND POLICY APPLICATIONS</subject><subject>Coronary vessels</subject><subject>Exercise</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental health</subject><subject>Public Health</subject><subject>Quality of life</subject><subject>Quality of Life Research</subject><subject>Sociology</subject><subject>Vein & artery diseases</subject><subject>Well being</subject><issn>0962-9343</issn><issn>1573-2649</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kUuPFCEUhYnROD2tf8BEQ-JmNqVcoChYmsn4SCZxo2tCwy2tthp6gMpM_3vRGsfEhQtyF3zn3Mch5AWwN8DY8LYAgFAd49CelrI7PSIb6AfRcSXNY7JhRvHOCCnOyHkpe8aYNow_JWdCaCOMgA3ZXd1h9lNBWtOM2UWP1MVAbxY3T_VE00jnaUQ6RXp0dcJYC72d6nf6I6bbSFOmZSlH9BUD9Smn6PKJulyxldBsXcFn5Mno5oLP7-uWfH1_9eXyY3f9-cOny3fXnRdmqJ3xRgIfBxW4hDAOwfds9ABBDQ7BcamZk1ILHwwYyfQuSI1G6XFngvGoxJZcrL7HnG4WLNUepuJxnl3EtBTLe9Cc94wPDX39D7pPS45tukYpBVLJdtot4Svlcyol42iPeTq0BS0w-ysBuyZgWwL2dwL21ESv7q2X3QHDg-TPyRsgVqC0r_gN89_e_7V9uar2pab84Cr10ENvpPgJI3Kbzw</recordid><startdate>20210901</startdate><enddate>20210901</enddate><creator>Katsi, Vasiliki</creator><creator>Georgiopoulos, Georgios</creator><creator>Mitropoulou, Panagiota</creator><creator>Kontoangelos, Konstantinos</creator><creator>Kollia, Zoi</creator><creator>Tzavara, Chara</creator><creator>Soulis, Dimitrios</creator><creator>Toutouzas, Konstantinos</creator><creator>Oikonomou, Dimitrios</creator><creator>Aimo, Alberto</creator><creator>Tsioufis, Konstantinos</creator><general>Springer Science + Business Media</general><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>KB0</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20210901</creationdate><title>Exercise tolerance and quality of life in patients with known or suspected coronary artery disease</title><author>Katsi, Vasiliki ; Georgiopoulos, Georgios ; Mitropoulou, Panagiota ; Kontoangelos, Konstantinos ; Kollia, Zoi ; Tzavara, Chara ; Soulis, Dimitrios ; Toutouzas, Konstantinos ; Oikonomou, Dimitrios ; Aimo, Alberto ; Tsioufis, Konstantinos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-9c9412f76d241df7dc50fc11d67ae1a2480a4483cd919408bd48e968fb9d9ce63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Cardiovascular disease</topic><topic>CLINICAL AND POLICY APPLICATIONS</topic><topic>Coronary vessels</topic><topic>Exercise</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mental health</topic><topic>Public Health</topic><topic>Quality of life</topic><topic>Quality of Life Research</topic><topic>Sociology</topic><topic>Vein & artery diseases</topic><topic>Well being</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Katsi, Vasiliki</creatorcontrib><creatorcontrib>Georgiopoulos, Georgios</creatorcontrib><creatorcontrib>Mitropoulou, Panagiota</creatorcontrib><creatorcontrib>Kontoangelos, Konstantinos</creatorcontrib><creatorcontrib>Kollia, Zoi</creatorcontrib><creatorcontrib>Tzavara, Chara</creatorcontrib><creatorcontrib>Soulis, Dimitrios</creatorcontrib><creatorcontrib>Toutouzas, Konstantinos</creatorcontrib><creatorcontrib>Oikonomou, Dimitrios</creatorcontrib><creatorcontrib>Aimo, Alberto</creatorcontrib><creatorcontrib>Tsioufis, Konstantinos</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical 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NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Quality of life research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Katsi, Vasiliki</au><au>Georgiopoulos, Georgios</au><au>Mitropoulou, Panagiota</au><au>Kontoangelos, Konstantinos</au><au>Kollia, Zoi</au><au>Tzavara, Chara</au><au>Soulis, Dimitrios</au><au>Toutouzas, Konstantinos</au><au>Oikonomou, Dimitrios</au><au>Aimo, Alberto</au><au>Tsioufis, Konstantinos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Exercise tolerance and quality of life in patients with known or suspected coronary artery disease</atitle><jtitle>Quality of life research</jtitle><stitle>Qual Life Res</stitle><addtitle>Qual Life Res</addtitle><date>2021-09-01</date><risdate>2021</risdate><volume>30</volume><issue>9</issue><spage>2541</spage><epage>2550</epage><pages>2541-2550</pages><issn>0962-9343</issn><eissn>1573-2649</eissn><abstract>Background
Coronary artery disease (CAD) is known to impact on patients’ physical and mental health. The relationship between performance on treadmill exercise tolerance test (ETT) and health-related quality of life (HRQL)has never been specifically investigated in the setting of CAD.
Methods
Consecutive patients undergoing an ETT with the Bruce protocol during a diagnostic workup for CAD (
n
= 1,631, age 55 ± 12 years) were evaluated. Exercise-related indices were recorded. Detailed information on cardiovascular risk factors and past medical history were obtained. HRQLwas assessed with the use of the validated 36-Item Short Form Survey (SF-36) questionnaire.
Results
Increasing age and the presence of cardiovascular risk factors and comorbidities correlated with lower scores on the physical and mental health component of SF-36(all
P
< 0.05). Subjects with arrhythmias during exercise and slow recovery of systolic blood pressure had lower scores on the physical health indices or the Social Role Functioning component (
P
< 0.05). Achieved target heart rate and good exercise tolerance were independently associated with better scores of the physical and mental health domains of SF-36 and overall HRQLscores (β = 0.05 for target HR and PCS-36, β = 1.86 and β = 1.66 per increasing stage of exercise tolerance and PCS-36 and MCS-36, respectively,
P
< 0.001 for all associations). Ischemic ECG changes were associated with worse scores on Physical Functioning (β = − 3.2,
P
= 0.02) and Bodily Pain (β = − 4.55,
P
= 0.026).
Conclusion
ETT parameters are associated with HRQL indices in patients evaluated for possible CAD. Physical conditioning may increase patient well-being and could serve as a complementary target in conjunction with cardiovascular drug therapy.</abstract><cop>Cham</cop><pub>Springer Science + Business Media</pub><pmid>33893931</pmid><doi>10.1007/s11136-021-02844-y</doi><tpages>10</tpages></addata></record> |
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| source | Springer Nature - Complete Springer Journals |
| subjects | Cardiovascular disease CLINICAL AND POLICY APPLICATIONS Coronary vessels Exercise Medicine Medicine & Public Health Mental health Public Health Quality of life Quality of Life Research Sociology Vein & artery diseases Well being |
| title | Exercise tolerance and quality of life in patients with known or suspected coronary artery disease |
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