Early-life exposure to the Chinese famine, genetic susceptibility and the risk of type 2 diabetes in adulthood

Aims/hypothesis Early famine exposure has been related to the development of type 2 diabetes; however, little is known about whether the genetic background modifies this association. We aimed to investigate the joint effects of famine exposure at different stages of early life and genetic susceptibi...

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Veröffentlicht in:	Diabetologia 2021-08, Vol.64 (8), p.1766-1774
Hauptverfasser:	Wang, Bin, Cheng, Jing, Wan, Heng, Wang, Yuying, Zhang, Wen, Chen, Yi, Chen, Chi, Xia, Fangzhen, Jensen, Michael D., Wang, Ningjian, Lu, Yingli
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Adult Age Aged Asians - ethnology Blood Glucose - metabolism Child development Children China - epidemiology Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - physiopathology Economic Status Famine Female Fetuses Genetic Predisposition to Disease Human Physiology Humans Internal Medicine Lipids - blood Logistic Models Male Medicine Medicine & Public Health Metabolic Diseases Metabolic disorders Middle Aged Polymorphism, Single Nucleotide Population genetics Pregnancy Prenatal experience Prenatal exposure Prenatal Exposure Delayed Effects - epidemiology Prevalence Risk Factors Rural Population - statistics & numerical data Single photon emission computed tomography Starvation - epidemiology Starvation - physiopathology Surveys and Questionnaires Teenagers Urban Population - statistics & numerical data
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