Genomic and in vitro pharmacodynamic analysis of rifampicin resistance in multidrug‐resistant canine Staphylococcus pseudintermedius isolates

Background Antimicrobial resistance is a growing concern in canine Staphylococcus pseudintermedius dermatitis. Treatment with rifampicin (RFP) is considered only in meticillin‐resistant and multidrug‐resistant S. pseudintermedius (MDR‐MRSP). Hypothesis/Objectives To determine an optimal RFP dosing f...

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Veröffentlicht in:	Veterinary dermatology 2021-06, Vol.32 (3), p.219-e67
Hauptverfasser:	Hicks, Karly, Tan, Yongjun, Cao, Wenqi, Hathcock, Terri, Boothe, Dawn, Kennis, Robert, Zhang, Dapeng, Wang, Xu, White, Amelia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antibiotics Antimicrobial agents Antimicrobial resistance canine Dermatitis Dog Diseases - drug therapy Dogs Dosage Drug resistance Genes Genomes Genomic analysis Genomics Methicillin Methicillin Resistance Microbial Sensitivity Tests - veterinary Minimum inhibitory concentration multidrug resistance Mutation Pharmacodynamics Pyoderma rifampicin Rifampin Rifampin - pharmacology RpoB protein Staphylococcal Infections - drug therapy Staphylococcal Infections - veterinary Staphylococcus - genetics Staphylococcus pseudintermedius
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