The fibrillin‐1 RGD motif posttranscriptionally regulates ERK1/2 signaling and fibroblast proliferation via miR‐1208

Fibrillin‐1 is an extracellular matrix protein which contains one conserved RGD integrin‐binding motif. It constitutes the backbone of microfibrils in many tissues, and mutations in fibrillin‐1 cause various connective tissue disorders. Although it is well established that fibrillin‐1 interacts with...

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Veröffentlicht in:	The FASEB journal 2021-05, Vol.35 (5), p.e21598-n/a
Hauptverfasser:	Zhang, Rong‐Mo, Zeyer, Karina A., Odenthal, Nadine, Zhang, Yiyun, Reinhardt, Dieter P.
Format:	Artikel
Sprache:	eng
Schlagworte:	ERK1/2 signaling fibrillin‐1 fibroblasts miR‐1208 proliferation RGD
Online-Zugang:	Volltext
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