Cartiotonic steroids affect monolayer permeability in lymphatic endothelial cells

Edema is common in preeclampsia (preE), a hypertensive disorder of pregnancy. Cardiotonic steroids (CTSs) such as marinobufagenin (MBG) are involved in the pathogenesis of preE. To assess whether CTSs are involved in the leakage of lymphatic endothelial cell (LEC), we evaluated their effect on monol...

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Veröffentlicht in:	Molecular and cellular biochemistry 2021-08, Vol.476 (8), p.3207-3213
Hauptverfasser:	Horvat, Darijana, Afroze, Syeda H., Cromer, Walter E., Pantho, Ahmed F., Ashraf, A. H. M. Zuberi, Kuehl, Thomas J., Zawieja, David C., Uddin, Mohammad Nasir
Format:	Artikel
Sprache:	eng
Schlagworte:	Aprotinin Arginine Biochemistry Biomedical and Life Sciences Cadherins Cardiology Cell Biology Cell culture Edema Endothelial cells Endothelium Fluorescence Hypertension Immunofluorescence Life Sciences Life Sciences & Biomedicine Light levels Medical Biochemistry Membrane permeability Monolayers Muscle proteins Myosin NG-Nitroarginine methyl ester Nitric oxide Oncology Ouabain Pathogenesis Permeability Phosphorylation Pre-eclampsia Preeclampsia Pregnancy Pretreatment Science & Technology Signal transduction Steroid hormones Steroids Tight junctions Vascular leak syndrome β-Catenin
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