Impaired myeloid-derived suppressor cells are associated with recurrent implantation failure: A case-control study

•RIF patients showed significant reductions of blood PMN-MDSCs, M-MDSCs, Tregs and NO production by PMN-MDSCs.•The expression of ζ chain on CD4+ TCR and CD8+TCR displayed a remarkable upregulation in RIF patients.•RIF patients presented a lower concentration of CCL5 and TGF-β.•TCR ζ chain on CD4+ an...

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