Current treatment options for HER2-positive breast cancer patients with brain metastases

[Display omitted] •Brain metastases are a frequent complication of HER2-positive breast cancer.•Treatment options include surgery, radiation and systemic therapy.•Trastuzumab plus pertuzumab, trastuzumab-emtansine and lapatinib are widely used.•Novel HER2-targeted agents recently showed promising ac...

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Veröffentlicht in:	Critical reviews in oncology/hematology 2021-05, Vol.161, p.103329-103329, Article 103329
Hauptverfasser:	Galanti, Daniele, Inno, Alessandro, La Vecchia, Maria, Borsellino, Nicolò, Incorvaia, Lorena, Russo, Antonio, Gori, Stefania
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain metastases HER2-positive breast cancer Lapatinib Neratinib Trastuzumab Trastuzumab deruxtecan Trastuzumab-emtansine Tucatinib
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