Remifentanil preconditioning promotes liver regeneration via upregulation of β-arrestin 2/ERK/cyclin D1 pathway

Remifentanil is a potent, short-acting opioid analgesic drug that can protect tissues from ischemia and reperfusion injury though anti-inflammatory effects. However, the utility of remifentanil in liver regeneration after hepatectomy is not known. Using a 70% hepatectomy mouse model (PHx), we found...

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Veröffentlicht in:	Biochemical and biophysical research communications 2021-06, Vol.557, p.69-76
Hauptverfasser:	Zhu, Ling, Zhou, Yan-Yu, Zhang, Zhi, Yin, Su-Qing, Lv, Dong-Dong, Wu, Yu-Ling, Wang, Bao-Shan, Mao, Meng-Han, Jiao, Ying-Fu, Yu, Wei-Feng, Gao, Po, Yang, Li-Qun
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell proliferation Liver regeneration Remifentanil β-arrestin 2
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